Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein (Q27659586)

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17 January 2020

title

Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein (English)

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17 January 2020

influenza A virus

1 reference

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17 January 2020

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17 January 2020

1 reference

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17 January 2020

Philip S Kerry

1 reference

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17 January 2020

David Jackson

1 reference

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17 January 2020

Bernard L Precious

1 reference

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17 January 2020

Marian J Killip

1 reference

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17 January 2020

Rupert J Russell

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17 January 2020

language of work or name

English

0 references

publication date

19 January 2010

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

17 January 2020

number of pages

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based on heuristic

inferred from page(s)

published in

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17 January 2020

volume

107

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17 January 2020

issue

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17 January 2020

page(s)

1954-1959

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Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation

17 January 2020

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1 reference

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A frequent kinase domain mutation that changes the interaction between PI3K and the membrane

20 March 2017

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Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

20 March 2017

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Structure of NS1A effector domain from the influenza A/Udorn/72 virus

20 March 2017

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X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus

20 March 2017

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20 March 2017

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Structural basis for suppression of a host antiviral response by influenza A virus

20 March 2017

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Structure of an avian influenza A virus NS1 protein effector domain

20 March 2017

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The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

20 March 2017

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Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit

20 March 2017

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AKT/PKB signaling: navigating downstream

20 March 2017

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The NPro Product of Bovine Viral Diarrhea Virus Inhibits DNA Binding by Interferon Regulatory Factor 3 and Targets It for Proteasomal Degradation

20 March 2017

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Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling

20 March 2017

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20 March 2017

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20 March 2017

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The CCP4 suite: programs for protein crystallography

20 March 2017

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PHENIX: building new software for automated crystallographic structure determination

20 March 2017

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20 March 2017

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The phosphoinositide 3-kinase pathway

22 April 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

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High frequency of mutations of the PIK3CA gene in human cancers

20 March 2017

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The multifunctional NS1 protein of influenza A viruses

20 March 2017

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Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins

20 March 2017

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Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidylinositol 3-kinase (PI3K).

7 April 2017

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Cation currents in human airway epithelial cells induced by infection with influenza A virus.

29 September 2017

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Mechanism of influenza A virus NS1 protein interaction with the p85beta, but not the p85alpha, subunit of phosphatidylinositol 3-kinase (PI3K) and up-regulation of PI3K activity

29 September 2017

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Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation

29 September 2017

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SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation

29 September 2017

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A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis

29 September 2017

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Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses

29 September 2017

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PTEN M-CBR3, a versatile and selective regulator of inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5). Evidence for Ins(1,3,4,5,6)P5 as a proliferative signal

29 September 2017

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Degradation of STAT1 and STAT2 by the V proteins of simian virus 5 and human parainfluenza virus type 2, respectively: consequences for virus replication in the presence of alpha/beta and gamma interferons

29 September 2017

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Rescue of influenza A virus from recombinant DNA.

29 September 2017

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Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts

29 September 2017

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Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling

2 June 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0910715107

Differential regulation of antiviral and proinflammatory cytokines and suppression of Fas-mediated apoptosis by NS1 of H9N2 avian influenza virus in chicken macrophages

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0910715107

X-ray structure of influenza virus NS1 effector domain

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0910715107

21 January 2018

Identifiers

DOI

10.1073/PNAS.0910715107

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133840%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

ADS bibcode

2010PNAS..107.1954H

0 references

1 reference

2 references

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17 January 2020

PubMed publication ID

20133840

2 references

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