Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme (Q27637096)

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Reciprocal communication between the lyase and synthase active sites of the tryptophan synthase bienzyme complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Monovalent cations affect dynamic and functional properties of the tryptophan synthase alpha 2 beta 2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Allosteric regulation of tryptophan synthase: effects of pH, temperature, and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate-L-serine intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Allosteric interactions coordinate catalytic activity between successive metabolic enzymes in the tryptophan synthase bienzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

beta-Site covalent reactions trigger transitions between open and closed conformations of the tryptophan synthase bienzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Loop closure and intersubunit communication in tryptophan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Characterization of the functional role of a flexible loop in the alpha-subunit of tryptophan synthase from Salmonella typhimurium by rapid-scanning, stopped-flow spectroscopy and site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Allosteric communication of tryptophan synthase. Functional and regulatory properties of the beta S178P mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Novel allosteric effectors of the tryptophan synthase alpha(2)beta(2) complex identified by computer-assisted molecular modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Crystal structure of wild-type tryptophan synthase complexed with the natural substrate indole-3-glycerol phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Efficient anisotropic refinement of macromolecular structures using FFT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Automated refinement of protein models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Size and chemical composition of influenza virus hemagglutinin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Tryptophan synthase from Escherichia coli and Salmonella typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Cryocrystallography and microspectrophotometry of a mutant (alpha D60N) tryptophan synthase alpha 2 beta 2 complex reveals allosteric roles of alpha Asp60

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant (alphaD60N) tryptophan synthase alpha2beta2 complex reveals the correct orientation of active site alphaGlu49

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Roles of hydrogen bonding residues in the interaction between the alpha and beta subunits in the tryptophan synthase complex. Asn-104 of the alpha subunit is especially important.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Substitution of glutamic acid 109 by aspartic acid alters the substrate specificity and catalytic activity of the beta-subunit in the tryptophan synthase bienzyme complex from Salmonella typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Raster3D Version 2.0. A program for photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

The mechanism of tryptophan binding to tryptophan synthase from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Mutations in the contact region between the alpha and beta subunits of tryptophan synthase alter subunit interaction and intersubunit communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Arytetralin lignans from Linum catharticum L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200

Monovalent cations partially repair a conformational defect in a mutant tryptophan synthase alpha 2 beta 2 complex (beta-E109A)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111031200