Analysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population Level (Q27485493)

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Jing Jing Wang

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Shadi Salloum

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Gagandeep S Narula

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Anna Eckart

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Andrea Biezynski

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Thomas Eiermann

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Sergei Viazov

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Michael Roggendorf

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Robert Thimme

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Markus Reiser

The C Terminus of Hepatitis C Virus NS4A Encodes an Electrostatic Switch That Regulates NS5A Hyperphosphorylation and Viral Replication

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publication date

April 2008

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3438-51

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cites work

1 reference

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Evidence of Viral Adaptation to HLA Class I-Restricted Immune Pressure in Chronic Hepatitis C Virus Infection

20 March 2017

1 reference

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Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Relation between viral fitness and immune escape within the hepatitis C virus protease

20 March 2017

1 reference

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Robust hepatitis C virus infection in vitro

20 March 2017

1 reference

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Divergent and convergent evolution after a common-source outbreak of hepatitis C virus

20 March 2017

1 reference

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Cellular immune selection with hepatitis C virus persistence in humans

20 March 2017

1 reference

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Immune evasion versus recovery after acute hepatitis C virus infection from a shared source

20 March 2017

1 reference

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CD8 Epitope Escape and Reversion in Acute HCV Infection

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Hepatitis C Virus NS3 ATPases/Helicases from Different Genotypes Exhibit Variations in Enzymatic Properties

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Comprehensive Analysis of CD8+-T-Cell Responses against Hepatitis C Virus Reveals Multiple Unpredicted Specificities

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Complete replication of hepatitis C virus in cell culture

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Dating of the human-ape splitting by a molecular clock of mitochondrial DNA

20 March 2017

1 reference

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Determinants of viral clearance and persistence during acute hepatitis C virus infection

20 March 2017

1 reference

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Adaptive immune responses in acute and chronic hepatitis C virus infection

20 March 2017

1 reference

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The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes

7 April 2017

1 reference

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The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target

9 May 2017

1 reference

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De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+-T-cell responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Consequences of cytotoxic T-lymphocyte escape: common escape mutations in simian immunodeficiency virus are poorly recognized in naive hosts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

The nonstructural protein 3 protease/helicase requires an intact protease domain to unwind duplex RNA efficiently

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Advantage of rare HLA supertype in HIV disease progression

29 September 2017

1 reference

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Lack of strong immune selection pressure by the immunodominant, HLA-A*0201-restricted cytotoxic T lymphocyte response in chronic human immunodeficiency virus-1 infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus

29 September 2017

1 reference

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Endogenous peptides with distinct amino acid anchor residue motifs bind to HLA-A1 and HLA-B8.

29 September 2017

1 reference

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Vaccine-induced T cells control reversion of AIDS virus immune escape mutants

29 September 2017

1 reference

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High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection

2 June 2018

1 reference

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Relationship among immunodominance of single CD8+ T cell epitopes, virus load, and kinetics of primary antiviral CTL response

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Human leukocyte antigen-associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Absence of viral escape within a frequently recognized HLA-A26-restricted CD8+ T-cell epitope targeting the functionally constrained hepatitis C virus NS5A/5B cleavage site

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Founder Effects in the Assessment of HIV Polymorphisms and HLA Allele Associations

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

CTL response compensation for the loss of an immunodominant class I-restricted HSV-1 determinant

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Positive selection of cytotoxic T lymphocyte escape variants during acute hepatitis C virus infection

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

The Los Alamos hepatitis C sequence database

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Reversion of CTL escape–variant immunodeficiency viruses in vivo

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

HIV evolution: CTL escape mutation and reversion after transmission

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Low frequency of cirrhosis in a hepatitis C (genotype 1b) single-source outbreak in germany: a 20-year multicenter study

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268453

Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18216107

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Definition of specific peptide motifs for four major HLA-A alleles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18216107

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18216107