Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif. (Q27334411)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25991062%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif (English)

1 reference

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RNA recognition motif domain

8 March 2020

main subject

1 reference

1 reference

1 reference

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8 March 2020

1 reference

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8 March 2020

1 reference

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8 March 2020

1 reference

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8 March 2020

Hannah K Robinson

1 reference

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8 March 2020

Evgeny V Bronovitsky

1 reference

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8 March 2020

Ruslan K Ovchinnikov

1 reference

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8 March 2020

Tatyana A Shelkovnikova

1 reference

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8 March 2020

Tatyana G Ermolkevich

1 reference

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8 March 2020

Igor L Goldman

1 reference

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8 March 2020

Elena A Kovrazhkina

1 reference

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8 March 2020

Sergey O Bachurin

1 reference

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8 March 2020

Vladimir L Buchman

1 reference

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8 March 2020

Natalia N Ninkina

1 reference

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8 March 2020

language of work or name

English

0 references

publication date

20 May 2015

1 reference

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Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

8 March 2020

published in

1 reference

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8 March 2020

volume

1 reference

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8 March 2020

issue

5-6

1 reference

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8 March 2020

page(s)

402-409

1 reference

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Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis

8 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration

21 March 2017

1 reference

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ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

21 March 2017

1 reference

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TLS inhibits RNA polymerase III transcription

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease

21 March 2017

1 reference

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Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Analyzing real-time PCR data by the comparative C(T) method

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Identification of an RNA binding specificity for the potential splicing factor TLS

21 March 2017

1 reference

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FUS pathology in basophilic inclusion body disease

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines

21 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

21 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Domain architectures and characterization of an RNA-binding protein, TLS

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long-term potentiation

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

RNA recognition motifs: boring? Not quite

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Stress granules: the Tao of RNA triage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Kinesin transports RNA: isolation and characterization of an RNA-transporting granule

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Compromised paraspeckle formation as a pathogenic factor in FUSopathies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Modelling FUSopathies: focus on protein aggregation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

ALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

The RRM domain of human fused in sarcoma protein reveals a non-canonical nucleic acid binding site.

29 September 2017

1 reference

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Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

TLS/FUS (translocated in liposarcoma/fused in sarcoma) regulates target gene transcription via single-stranded DNA response elements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

TDP-43 and FUS RNA-binding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-transcriptional fate in motoneuron-like cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Gamma-synucleinopathy: neurodegeneration associated with overexpression of the mouse protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43)

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811325

Novel FUS/TLS mutations and pathology in familial and sporadic amyotrophic lateral sclerosis.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.3109%2F21678421.2015.1040994

FUS mutations in amyotrophic lateral sclerosis: clinical, pathological, neurophysiological and genetic analysis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.3109%2F21678421.2015.1040994

Hypoglossal, trigeminal, and facial motoneuron involvement in amyotrophic lateral sclerosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25991062

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3109/21678421.2015.1040994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25991062%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

8 March 2020

3662269

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3662269

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25991062%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

25991062

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25991062%20AND%20SRC:MED&resulttype=core&format=json