Uncovering the role of p53 splice variants in human malignancy: a clinical perspective (Q27015641)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Uncovering the role of p53 splice variants in human malignancy: a clinical perspective (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author

Jean-Christophe Bourdon

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Sylvanie Surget

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Marie P Khoury

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

language of work or name

1 reference

19 December 2013

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

published in

OncoTargets and Therapy

2 references

Crossref

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

57-68

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

4 March 2020

start time

1 December 2013

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

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Intron 3 sixteen base pairs duplication polymorphism of p53 contributes to breast cancer susceptibility: evidence from meta-analysis

28 September 2017

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p53 protein isoforms: key regulators in the front line of pathogen infections?

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Host microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses reveal an unanticipated antiviral activity for miR-146a

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28 September 2017

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28 September 2017

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Annexin A2 and PSF proteins interact with p53 IRES and regulate translation of p53 mRNA.

28 September 2017

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28 September 2017

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Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses

28 September 2017

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28 September 2017

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28 September 2017

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The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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p53 Isoforms: An Intracellular Microprocessor?

28 September 2017

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The emerging role of pre-messenger RNA splicing in stress responses: sending alternative messages and silent messengers

28 September 2017

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Recent Advances in the Therapeutic Perspectives of Nutlin-3

28 September 2017

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Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice.

28 September 2017

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28 September 2017

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28 September 2017

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p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients.

28 September 2017

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Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs

28 September 2017

1 reference

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Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies

28 September 2017

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Heterochromatin silencing of p53 target genes by a small viral protein

28 September 2017

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p53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damage

28 September 2017

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28 September 2017

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p63 and p73, the ancestors of p53.

28 September 2017

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Posttranslational modification of p53: cooperative integrators of function

28 September 2017

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28 September 2017

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p53 regulates the transcription of its Delta133p53 isoform through specific response elements contained within the TP53 P2 internal promoter

28 September 2017

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p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence

28 September 2017

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28 September 2017

1 reference

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Polypyrimidine tract binding protein regulates IRES-mediated translation of p53 isoforms.

28 September 2017

1 reference

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Regulation of programmed cell death by the p53 pathway.

28 September 2017

1 reference

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Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA-damaging agent cisplatin.

28 September 2017

1 reference

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Expression levels of p53 and p73 isoforms in stage I and stage III ovarian cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Reactivation of mutant p53: molecular mechanisms and therapeutic potential

28 September 2017

1 reference

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p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.

28 September 2017

1 reference

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Two internal ribosome entry sites mediate the translation of p53 isoforms.

28 September 2017

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28 September 2017

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A novel human p53 isoform is an essential element of the ATR-intra-S phase checkpoint

28 September 2017

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Human tumor suppressor p53 and DNA viruses

28 September 2017

1 reference

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Modulation of mammalian life span by the short isoform of p53.

28 September 2017

1 reference

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Functional regulation of p73 and p63: development and cancer

28 September 2017

1 reference

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Decision making by p53: life, death and cancer

28 September 2017

1 reference

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TP53 family members and human cancers

28 September 2017

1 reference

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The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

28 September 2017

1 reference

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Regulation of the G2/M transition by p53.

28 September 2017

1 reference

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Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

28 September 2017

1 reference

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Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

28 September 2017

1 reference

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Role of the p53 Protein in Cell Proliferation as Studied by Microinjection of Monoclonal Antibodies

28 September 2017

1 reference

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Immunologically distinct p53 molecules generated by alternative splicing

28 September 2017

1 reference

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Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation

28 September 2017

1 reference

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Isolation of a full-length mouse cDNA clone coding for an immunologically distinct p53 molecule

28 September 2017

1 reference

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Wild-type p53 can inhibit oncogene-mediated focus formation

28 September 2017

1 reference

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The p53 proto-oncogene can act as a suppressor of transformation

28 September 2017

1 reference

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The p53 tumour suppressor gene

28 September 2017

1 reference

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A transcriptionally active DNA-binding site for human p53 protein complexes

28 September 2017

1 reference

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Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

28 September 2017

1 reference

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The human tumour suppressor gene p53 is alternatively spliced in normal cells

28 September 2017

1 reference

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Glucose Tolerance in Mice is Linked to the Dose of the p53 Transactivation Domain

28 September 2017

1 reference

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Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript.

31 May 2018

1 reference

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Detailed haplotype analysis at the TP53 locus in p.R337H mutation carriers in the population of Southern Brazil: evidence for a founder effect.

31 May 2018

1 reference

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Expression of p53 isoforms in squamous cell carcinoma of the head and neck

31 May 2018

1 reference

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Molecular cloning and functional characterization of the upstream promoter region of the human p73 gene

31 May 2018

1 reference

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Genetic alterations in the p53 gene in the blast crisis of chronic myelogenous leukemia: analysis by polymerase chain reaction based techniques

31 May 2018

1 reference

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

31 May 2018

1 reference

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Growth regulation of a cellular tumour antigen, p53, in nontransformed cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Loss of a highly conserved domain on p53 as a result of gene deletion during Friend virus-induced erythroleukemia

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Ratio disruption of the ∆133p53 and TAp53 isoform equilibrium correlates with poor clinical outcome in intrahepatic cholangiocarcinoma.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Effect of a natural mutation in the 5' untranslated region on the translational control of p53 mRNA.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

The N-terminally truncated p53 isoform Δ40p53 influences prognosis in mucinous ovarian cancer.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

The p53 family: guardians of maternal reproduction

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Alternative splicing of p53 and p73: the novel p53 splice variant p53delta is an independent prognostic marker in ovarian cancer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Expression of p53 isoforms in renal cell carcinoma.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3872270

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

28 November 2018

1 reference

12 December 2020

High levels of p53 protein in UV-irradiated normal human skin

1 reference

12 December 2020

p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha

1 reference

12 December 2020

p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products

1 reference

12 December 2020

A distinct p53 protein isoform signature reflects the onset of induction chemotherapy for acute myeloid leukemia

1 reference

12 December 2020

Identifiers

DOI

10.2147/OTT.S53876

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

24379683

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379683%20AND%20SRC:MED&resulttype=core&format=json