The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis (Q26786969)

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Renea P Jablonski

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David B Williams

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David W Kamp

International Journal of Molecular Sciences

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language of work or name

English

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publication date

2015

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7 September 2015

6 references

2 August 2019

9 October 2019

12 October 2019

20 September 2020

20 December 2020

3 October 2022

6 references

2 August 2019

9 October 2019

12 October 2019

20 September 2020

20 December 2020

3 October 2022

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21486-519

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Creative Commons Attribution

6 references

2 August 2019

9 October 2019

12 October 2019

20 September 2020

20 December 2020

3 October 2022

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Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

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p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylase

7 April 2017

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SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

7 April 2017

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

7 April 2017

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SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70

7 April 2017

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The Nalp3 inflammasome is essential for the development of silicosis

7 April 2017

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Premature ageing in mice expressing defective mitochondrial DNA polymerase

7 April 2017

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Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration

7 April 2017

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Telomerase and idiopathic pulmonary fibrosis

7 April 2017

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Oxidative stress and pulmonary fibrosis

7 April 2017

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The pathways of mitophagy for quality control and clearance of mitochondria

7 April 2017

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Mitochondrial DNA damage and its consequences for mitochondrial gene expression

7 April 2017

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First Observation of C P Violation in the Decays of B s 0 Mesons

7 April 2017

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Pulmonary fibrosis: patterns and perpetrators

7 April 2017

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

7 April 2017

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Aconitase couples metabolic regulation to mitochondrial DNA maintenance

7 April 2017

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Mitochondrial Cu,Zn-superoxide dismutase mediates pulmonary fibrosis by augmenting H2O2 generation

7 April 2017

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The protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway

7 April 2017

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7 April 2017

The hallmarks of aging

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A role for mitochondria in NLRP3 inflammasome activation

7 April 2017

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Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

7 April 2017

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Protective mechanisms of mitochondria and heart function in diabetes

7 April 2017

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Time-dependent and somatically acquired mitochondrial DNA mutagenesis and respiratory chain dysfunction in a scleroderma model of lung fibrosis

7 April 2017

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Randomized trial of acetylcysteine in idiopathic pulmonary fibrosis

7 April 2017

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Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging

7 April 2017

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Role of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesis

7 April 2017

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Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death

7 April 2017

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Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases

7 April 2017

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Pulmonary endpoints (lung carcinomas and asbestosis) following inhalation exposure to asbestos

7 April 2017

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A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos

7 April 2017

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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

7 April 2017

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Why do cancers have high aerobic glycolysis?

7 April 2017

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7 April 2017

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Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

7 April 2017

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Redox-dependent modulation of aconitase activity in intact mitochondria

7 April 2017

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Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice

7 April 2017

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Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

7 April 2017

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Mitochondrial membrane permeabilization in cell death

7 April 2017

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Mitochondria, oxidants, and aging

7 April 2017

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Sirtuin activators mimic caloric restriction and delay ageing in metazoans

7 April 2017

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Mitochondrial formation of reactive oxygen species

7 April 2017

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Mitochondria: in sickness and in health

7 April 2017

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Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

7 April 2017

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Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

7 April 2017

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

7 April 2017

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Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

7 April 2017

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Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

7 April 2017

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Mitochondrial quality control pathways as determinants of metabolic health

7 April 2017

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SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction

28 September 2017

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Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

28 September 2017

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BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension

28 September 2017

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Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteria-induced vascular injury in perfused rat lungs

28 September 2017

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Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis

28 September 2017

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The role of mitochondrial DNA mutation on neurodegenerative diseases

28 September 2017

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Vimentin regulates activation of the NLRP3 inflammasome.

28 September 2017

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Mitochondrial Variations in Non-Small Cell Lung Cancer (NSCLC) Survival

28 September 2017

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Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs

28 September 2017

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Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury

28 September 2017

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Rare variants in RTEL1 are associated with familial interstitial pneumonia

28 September 2017

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Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA.

28 September 2017

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PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis.

28 September 2017

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Resveratrol regulates mitochondrial reactive oxygen species homeostasis through Sirt3 signaling pathway in human vascular endothelial cells

28 September 2017

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Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging

28 September 2017

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Plasminogen activator inhibitor 1, fibroblast apoptosis resistance, and aging-related susceptibility to lung fibrosis

28 September 2017

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Role of the urokinase-fibrinolytic system in epithelial-mesenchymal transition during lung injury

28 September 2017

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Conversion of bone marrow mesenchymal stem cells into type II alveolar epithelial cells reduces pulmonary fibrosis by decreasing oxidative stress in rats

28 September 2017

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Sequential actions of SIRT1-RELB-SIRT3 coordinate nuclear-mitochondrial communication during immunometabolic adaptation to acute inflammation and sepsis.

28 September 2017

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Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease.

28 September 2017

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Decreased SIRT3 in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress

28 September 2017

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Sirt3 protects cortical neurons against oxidative stress via regulating mitochondrial Ca2+ and mitochondrial biogenesis

28 September 2017

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Sirtuin 3 interacts with Lon protease and regulates its acetylation status.

28 September 2017

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Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice

28 September 2017

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Adult Stem Cells and Diseases of Aging

28 September 2017

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Mitochondria in lung biology and pathology: more than just a powerhouse

28 September 2017

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Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance

28 September 2017

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Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial-nuclear interactions

28 September 2017

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RIP1 maintains DNA integrity and cell proliferation by regulating PGC-1α-mediated mitochondrial oxidative phosphorylation and glycolysis

28 September 2017

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Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer

28 September 2017

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Mitochondria-targeted Ogg1 and aconitase-2 prevent oxidant-induced mitochondrial DNA damage in alveolar epithelial cells

28 September 2017

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Partial reversal of skeletal muscle aging by restoration of normal NAD⁺ levels

28 September 2017

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The protein deacetylase SIRT3 prevents oxidative stress-induced keratinocyte differentiation

28 September 2017

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28 September 2017

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Resveratrol induces a mitochondrial complex I-dependent increase in NADH oxidation responsible for sirtuin activation in liver cells

28 September 2017

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The Witschi Hypothesis revisited after 35 years: genetic proof from SP-C BRICHOS domain mutations

28 September 2017

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Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice

28 September 2017

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Sirtuins in stress response: guardians of the genome.

28 September 2017

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Mechanistic links between aging and lung fibrosis

28 September 2017

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Superoxide mediates acute liver injury in irradiated mice lacking sirtuin 3.

28 September 2017

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Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress.

28 September 2017

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A mitochondrial bioenergetic etiology of disease

28 September 2017

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Mitochondrial matrix P53 sensitizes cells to oxidative stress

28 September 2017

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Molecular basis of asbestos-induced lung disease

28 September 2017

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28 September 2017

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Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis

28 September 2017

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28 September 2017

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Mitochondrial-targeted DNA repair enzyme 8-oxoguanine DNA glycosylase 1 protects against ventilator-induced lung injury in intact mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Regulation of mitochondrial F(o)F(1)ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977bp deletion of mitochondrial DNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial dysfunction and lipid accumulation in the human diaphragm during mechanical ventilation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Resveratrol has protective effects against airway remodeling and airway hyperreactivity in a murine model of allergic airways disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

trans-(-)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Targeting NOX enzymes in pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis of 27 studies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Telomerase deficiency does not alter bleomycin-induced fibrosis in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

SIRT3 gene expression: a link between inherited mitochondrial DNA variants and oxidative stress.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial DNA integrity may be a determinant of endothelial barrier properties in oxidant-challenged rat lungs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Cardiac overexpression of 8-oxoguanine DNA glycosylase 1 protects mitochondrial DNA and reduces cardiac fibrosis following transaortic constriction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Determinants and dynamics of genome accessibility

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Signalling pathways from NADPH oxidase-4 to idiopathic pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial complex I: a central regulator of the aging process.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

A key role for NOX4 in epithelial cell death during development of lung fibrosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Ethanol sensitizes mitochondria to the permeability transition by inhibiting deacetylation of cyclophilin-D mediated by sirtuin-3

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Angiotensin II blockade: a strategy to slow ageing by protecting mitochondria?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

p53 downregulates the gene expression of mitochondrial aconitase in human prostate carcinoma cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Rac1-mediated mitochondrial H2O2 generation regulates MMP-9 gene expression in macrophages via inhibition of SP-1 and AP-1

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Proteasomal regulation of pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial DNA mutations and human disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Role of mitochondrial hOGG1 and aconitase in oxidant-induced lung epithelial cell apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

The conserved role of sirtuins in chromatin regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial DNA mutations in disease, aging, and neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Extracellular superoxide dismutase in pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Human 8-oxoguanine DNA glycosylase suppresses the oxidative stress induced apoptosis through a p53-mediated signaling pathway in human fibroblasts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial mutations in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Proapoptotic Bid is required for pulmonary fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Oxidative phosphorylation dysfunction modulates expression of extracellular matrix--remodeling genes and invasion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial DNA, aconitase 'wraps' it up.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Role of mitochondrial DNA in toxic responses to oxidative stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

The contribution of mitochondria to common disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Precise determination of mitochondrial DNA copy number in human skeletal and cardiac muscle by a PCR-based assay: lack of change of copy number with age.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Increased localization and substrate activation of protein kinase C delta in lung epithelial cells following exposure to asbestos

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Oxidative stress in heart failure: the role of mitochondria.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Incorporation of tritiated thymidine by epithelial and interstitial cells in bronchiolar-alveolar regions of asbestos-exposed rats.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

The role of free radicals in asbestos-induced diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Intratracheal administration of mitochondrial DNA directly provokes lung inflammation through the TLR9-p38 MAPK pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Resveratrol improves high-fat diet induced insulin resistance by rebalancing subsarcolemmal mitochondrial oxidation and antioxidantion

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Sustained activation of toll-like receptor 9 induces an invasive phenotype in lung fibroblasts: possible implications in idiopathic pulmonary fibrosis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Activation of SIRT3 by resveratrol ameliorates cardiac fibrosis and improves cardiac function via the TGF-β/Smad3 pathway

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Injection of mitochondria into human cells leads to a rapid replacement of the endogenous mitochondrial DNA.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4613264

Revealing the pathogenic and aging-related mechanisms of the enigmatic idiopathic pulmonary fibrosis. an integral model

31 May 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Mitochondrial DNA repair of oxidative damage in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

An association selected polymorphisms of XRCC1, OGG1 and MUTYH gene and the level of efficiency oxidative DNA damage repair with a risk of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Role of p53-fibrinolytic system cross-talk in the regulation of quartz-induced lung injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

SIRT3 attenuates MPTP-induced nigrostriatal degeneration via enhancing mitochondrial antioxidant capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

SIRT3 deficiency impairs mitochondrial and contractile function in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

ε-Viniferin is more effective than its monomer resveratrol in improving the functions of vascular endothelial cells and the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Mutations in the tricarboxylic acid cycle enzyme, aconitase 2, cause either isolated or syndromic optic neuropathy with encephalopathy and cerebellar atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS160921486

Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis

21 January 2018

1 reference

12 December 2020

Resveratrol alleviates bleomycin-induced lung injury in rats

1 reference

12 December 2020

Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation

1 reference

12 December 2020

Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells

1 reference

12 December 2020

Aerosolized administration of N-acetylcysteine attenuates lung fibrosis induced by bleomycin in mice

1 reference

12 December 2020

1 reference

12 December 2020

Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS160921486

1 reference

1 reference

1 reference

PubMed publication ID

26370974

1 reference