In Vitro/In Vivo Toxicity Evaluation and Quantification of Iron Oxide Nanoparticles. (Q26779017)

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28 February 2020

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3 May 2021

In Vitro/In Vivo Toxicity Evaluation and Quantification of Iron Oxide Nanoparticles (English)

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organometallic compound

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3 May 2021

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28 February 2020

Ujwal S Patil

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28 February 2020

Shiva Adireddy

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Sree Mandava

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28 February 2020

Benjamin R Lee

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Douglas B Chrisey

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language of work or name

English

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publication date

15 October 2015

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3 May 2021

International Journal of Molecular Sciences

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issue

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page(s)

24417-24450

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Creative Commons Attribution

28 February 2020

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Superparamagnetic iron oxide based MRI contrast agents: Current status of clinical application

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Biological impact of superparamagnetic iron oxide nanoparticles for magnetic particle imaging of head and neck cancer cells

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28 September 2017

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28 September 2017

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Subtle cytotoxicity and genotoxicity differences in superparamagnetic iron oxide nanoparticles coated with various functional groups

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28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

cRGD-functionalized, DOX-conjugated, and ⁶⁴Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Pharmacokinetic parameters and tissue distribution of magnetic Fe(3)O(4) nanoparticles in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

The suitability of different cellular in vitro immunotoxicity and genotoxicity methods for the analysis of nanoparticle-induced events

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Cytotoxicity of iron oxide nanoparticles made from the thermal decomposition of organometallics and aqueous phase transfer with Pluronic F127.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Gene expression profiling reveals early cellular responses to intracellular magnetic labeling with superparamagnetic iron oxide nanoparticles

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Reactive oxygen species in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Commercialization of nanotechnology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Comparison of electron spin resonance spectroscopy and inductively-coupled plasma optical emission spectroscopy for biodistribution analysis of iron-oxide nanoparticles

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

A new approach for the in vitro identification of the cytotoxicity of superparamagnetic iron oxide nanoparticles.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Magnetic force microscopy of iron oxide nanoparticles and their cellular uptake

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

The influence of surface functionalization on the enhanced internalization of magnetic nanoparticles in cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Confounding experimental considerations in nanogenotoxicology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

In vitro toxicity testing of nanoparticles in 3D cell culture.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Detection and quantification of magnetically labeled cells by cellular MRI

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Accelerator mass spectrometry

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Nanotechnology and health safety--toxicity and risk assessments of nanostructured materials on human health.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

R2 and R2* mapping for sensing cell-bound superparamagnetic nanoparticles: in vitro and murine in vivo testing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Applicability and limitations of MR tracking of neural stem cells with asymmetric cell division and rapid turnover: the case of the shiverer dysmyelinated mouse brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Tomographic imaging using the nonlinear response of magnetic particles

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Phase I clinical evaluation of citrate-coated monocrystalline very small superparamagnetic iron oxide particles as a new contrast medium for magnetic resonance imaging

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Effect of PEG molecular weight on stability, T₂ contrast, cytotoxicity, and cellular uptake of superparamagnetic iron oxide nanoparticles (SPIONs)

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Labeling primary amine groups in peptides and proteins with N-hydroxysuccinimidyl ester modified Fe3O4@SiO2 nanoparticles containing cleavable disulfide-bond linkers

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Effects of DMSA-coated Fe3O4 nanoparticles on the transcription of genes related to iron and osmosis homeostasis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Redox behavior of magnetite: implications for contaminant reduction

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Superparamagnetic iron oxide: pharmacokinetics and toxicity

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

A functionalized superparamagnetic iron oxide colloid as a receptor directed MR contrast agent

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Nanorobotics control design: a collective behavior approach for medicine

31 May 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Potential application of superparamagnetic nanoparticles for extraction of bacterial genomic DNA from contaminated food and environmental samples.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Biological impact assessment of nanomaterial used in nanomedicine. introduction to the NanoTEST project

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Surface-mediated production of hydroxyl radicals as a mechanism of iron oxide nanoparticle biotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

In vitro evaluation of the cytotoxicity of iron oxide nanoparticles with different coatings and different sizes in A3 human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Size dependent biodistribution and toxicokinetics of iron oxide magnetic nanoparticles in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Degradability of superparamagnetic nanoparticles in a model of intracellular environment: follow-up of magnetic, structural and chemical properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Catalytic efficiency of iron(III) oxides in decomposition of hydrogen peroxide: competition between the surface area and crystallinity of nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Adsorption of hematite nanoparticles onto Caco-2 cells and the cellular impairments: effect of particle size

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Human intestinal epithelial cells exhibit a cellular response indicating a potential toxicity upon exposure to hematite nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Superparamagnetic iron oxide nanoparticles impair endothelial integrity and inhibit nitric oxide production.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

The role of reactive oxygen species in the genotoxicity of surface-modified magnetite nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Iron oxide nanoparticle-induced oxidative stress and genotoxicity in human skin epithelial and lung epithelial cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Polyacrylic acid-coated and non-coated iron oxide nanoparticles induce cytokine activation in human blood cells through TAK1, p38 MAPK and JNK pro-inflammatory pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Difference between Toxicities of Iron Oxide Magnetic Nanoparticles with Various Surface-Functional Groups against Human Normal Fibroblasts and Fibrosarcoma Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Crucial role of the protein corona for the specific targeting of nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Significance of cell "observer" and protein source in nanobiosciences

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Temperature: the "ignored" factor at the NanoBio interface.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Slight temperature changes affect protein affinity and cellular uptake/toxicity of nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

In vitro toxicity assessment of chitosan oligosaccharide coated iron oxide nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Amine-surface-modified superparamagnetic iron oxide nanoparticles interfere with differentiation of human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Synthesis, characterization and toxicological evaluation of iron oxide nanoparticles in human lung alveolar epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Effect of surface modification of silica nanoparticles on toxicity and cellular uptake by human peripheral blood lymphocytes in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Oxidative damage to biological macromolecules in human bone marrow mesenchymal stromal cells labeled with various types of iron oxide nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Surface charge and dosage dependent potential developmental toxicity and biodistribution of iron oxide nanoparticles in pregnant CD-1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Toxicity and tissue distribution of magnetic nanoparticles in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Quantitative control of active targeting of nanocarriers to tumor cells through optimization of folate ligand density

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Interference of ferric ions with ferrous iron quantification using the ferrozine assay

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

In vivo leukocyte labeling with intravenous ferumoxides/protamine sulfate complex and in vitro characterization for cellular magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Synthesis of acid-stabilized iron oxide nanoparticles and comparison for targeting atherosclerotic plaques: evaluation by MRI, quantitative MPS, and TEM alternative to ambiguous Prussian blue iron staining

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Quantitative X-ray imaging of intraplaque hemorrhage in aortas of apoE(-/-)/LDL(-/-) double knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Diffuse optical tomography guided quantitative fluorescence molecular tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

A fast and reproducible method to quantify magnetic nanoparticle biodistribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Integrity of (111)In-radiolabeled superparamagnetic iron oxide nanoparticles in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Analysis of Changes in Gene Expression and Metabolic Profiles Induced by Silica-Coated Magnetic Nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Ac magnetic susceptibility study ofin vivonanoparticle biodistribution

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Multifunctional Nanobeads Based on Quantum Dots and Magnetic Nanoparticles: Synthesis and Cancer Cell Targeting and Sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Superparamagnetic iron oxide nanoparticles change endothelial cell morphology and mechanics via reactive oxygen species formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

Magnetic Resonance Cell-Tracking Studies: Spectrophotometry-Based Method for the Quantification of Cellular Iron Content after Loading with Superparamagnetic Iron Oxide Nanoparticles

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4632758

Reactive Oxygen Species, Oxidative Damage, and Antioxidative Defense Mechanism in Plants under Stressful Conditions

28 November 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

A submillimeter resolution fluorescence molecular imaging system for small animal imaging

21 January 2018

1 reference

12 December 2020

Fenton-like oxidation of Rhodamine B in the presence of two types of iron (II, III) oxide

1 reference

12 December 2020

A new quantitative method to determine the uptake of SPIONs in animal tissue and its application to determine the quantity of nanoparticles in the liver and lung of Balb-c mice exposed to the SPIONs

1 reference

12 December 2020

The benefits of increasing spatial resolution as a means of reducing artifacts due to field inhomogeneities

1 reference

12 December 2020

Direct FLASH MR imaging of magnetic field inhomogeneities by gradient compensation

1 reference

12 December 2020

Spectrophotometric determination of serum iron at the submicrogram level with a new reagent (ferrozine)

1 reference

12 December 2020

Nanocrystalline Iron Oxides, Composites, and Related Materials as a Platform for Electrochemical, Magnetic, and Chemical Biosensors

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

7 January 2021

inferred from DOI database lookup

Silica-coated super-paramagnetic iron oxide nanoparticles (SPIONPs): a new type contrast agent of T1 magnetic resonance imaging (MRI)

1 reference

https://api.crossref.org/works/10.3390%2FIJMS161024417

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.3390/IJMS161024417

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26501258%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

28 February 2020

4176527

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4176527

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26501258%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

26501258

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26501258%20AND%20SRC:MED&resulttype=core&format=json