Glycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapy (Q26739711)

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20 March 2020

review article

2 references

8 February 2021

Glycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapy (English)

1 reference

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20 March 2020

1 reference

20 August 2019

glycogen synthase kinase 3 beta

1 reference

PubMed

antineoplastic resistance

28 September 2019

1 reference

26 October 2020

1 reference

8 February 2021

1 reference

1 reference

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20 March 2020

1 reference

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20 March 2020

Takahiro Domoto

1 reference

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20 March 2020

Takuya Furuta

1 reference

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20 March 2020

Masahiro Uehara

1 reference

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20 March 2020

Takeo Shimasaki

1 reference

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20 March 2020

Mitsutoshi Nakada

1 reference

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20 March 2020

Toshinari Minamoto

1 reference

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20 March 2020

language of work or name

1 reference

24 September 2016

1 reference

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20 March 2020

1 October 2016

2 references

26 October 2020

8 February 2021

8 references

3 April 2019

20 August 2019

28 September 2019

16 November 2019

20 November 2019

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20 March 2020

26 October 2020

8 February 2021

107

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20 March 2020

issue

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20 March 2020

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1363-1372

1 reference

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Creative Commons Attribution-NonCommercial-NoDerivatives

20 March 2020

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3 April 2019

20 August 2019

28 September 2019

16 November 2019

20 November 2019

26 October 2020

8 February 2021

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Tumorigenesis: it takes a village

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Inhibition of invasion by glycogen synthase kinase-3 beta inhibitors through dysregulation of actin re-organisation via down-regulation of WAVE2.

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Glycogen synthase kinase-3β inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth.

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Glycogen synthase kinase 3β inhibition sensitizes human glioblastoma cells to temozolomide by affecting O6-methylguanine DNA methyltransferase promoter methylation via c-Myc signaling.

28 September 2017

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28 September 2017

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Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy

28 September 2017

1 reference

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Combinatorial drug therapy for cancer in the post-genomic era.

28 September 2017

1 reference

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Distinct expression and activity of GSK-3α and GSK-3β in prostate cancer.

28 September 2017

1 reference

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Glycogen synthase kinase-3β, NF-κB signaling, and tumorigenesis of human osteosarcoma.

28 September 2017

1 reference

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The dark side of E2F1: in transit beyond apoptosis

28 September 2017

1 reference

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Cancer invasion and resistance: interconnected processes of disease progression and therapy failure

28 September 2017

1 reference

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Glycogen synthase kinase-3 (GSK-3) inhibition induces apoptosis in leukemic cells through mitochondria-dependent pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine

28 September 2017

1 reference

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Indirubins decrease glioma invasion by blocking migratory phenotypes in both the tumor and stromal endothelial cell compartments

28 September 2017

1 reference

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Suppression of glycogen synthase kinase 3 activity reduces tumor growth of prostate cancer in vivo

28 September 2017

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Glycogen synthase kinase-3beta: a prognostic marker and a potential therapeutic target in human bladder cancer

28 September 2017

1 reference

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Glycogen synthase kinase 3 regulates PAX3-FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells

28 September 2017

1 reference

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An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3 beta.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinase-3: a new therapeutic target in renal cell carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Deregulated GSK3{beta} sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinase 3 in the world of cell migration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinases-3beta controls differentiation of malignant glioma cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3).

28 September 2017

1 reference

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Potential therapeutic effect of glycogen synthase kinase 3beta inhibition against human glioblastoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

EMT, the cytoskeleton, and cancer cell invasion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Lamellipodia and filopodia in metastasis and invasion

28 September 2017

1 reference

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Detection of active fraction of glycogen synthase kinase 3beta in cancer cells by nonradioisotopic in vitro kinase assay

28 September 2017

1 reference

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Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinase-3beta positively regulates the proliferation of human ovarian cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Glycogen synthase kinase-3beta suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Combining targeted therapeutics in the era of precision medicine

28 September 2017

1 reference

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Targeting the RB-pathway in cancer therapy

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Maintenance of constitutive IkappaB kinase activity by glycogen synthase kinase-3alpha/beta in pancreatic cancer

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084660

Unravelling cancer stem cell potential.

31 May 2018

1 reference

Cancer Stem Cells and Chemosensitivity

21 January 2018

1 reference

Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells

21 January 2018

1 reference

Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth

21 January 2018

1 reference

21 January 2018

1 reference

GSK3β mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway

21 January 2018

1 reference

GSK-3 inhibition in vitro and in vivo enhances antitumor effect of sorafenib in renal cell carcinoma (RCC).

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/CAS.13028

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27486911%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27486911%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

27486911

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27486911%20AND%20SRC:MED&resulttype=core&format=json