Developmental Drift and the Role of Wnt Signaling in Aging (Q26739045)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27490570%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

review article

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title

Developmental Drift and the Role of Wnt Signaling in Aging (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27490570%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27490570%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Jan Gruber

1 reference

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20 March 2020

Zhuangli Yee

series ordinal

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20 March 2020

language of work or name

English

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publication date

2 August 2016

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20 March 2020

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20 March 2020

volume

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issue

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Creative Commons Attribution 4.0 International

20 March 2020

page(s)

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start time

2 August 2016

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Wnt/β-catenin signaling and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Wnt and TGF-beta expression in the sponge Amphimedon queenslandica and the origin of metazoan embryonic patterning

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Widespread protein aggregation as an inherent part of aging in C. elegans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The Wnt signaling pathway in development and disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Aging: a theory based on free radical and radiation chemistry

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Augmented Wnt signaling in a mammalian model of accelerated aging

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Genetic determinants of human health span and life span: progress and new opportunities

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Gerontogenes: real or virtual?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The biologic clock: the mitochondria?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Wnt signalling in stem cells and cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Mitochondria, oxidants, and aging

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Wnt signaling: a common theme in animal development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Towards an integrated view of Wnt signaling in development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The plasticity of aging: insights from long-lived mutants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Oxidative stress and life histories: unresolved issues and current needs.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Interventions to Slow Aging in Humans: Are We Ready?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Targeting Wnts at the source--new mechanisms, new biomarkers, new drugs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Caenorhabditis elegans: What We Can and Cannot Learn from Aging Worms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Obesity, diabetes and cancer: insight into the relationship from a cohort with growth hormone receptor deficiency

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Aging is not a disease: implications for intervention

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Developmental drift as a mechanism for aging: lessons from nematodes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Substantial health and economic returns from delayed aging may warrant a new focus for medical research

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

C. elegans GATA factors EGL-18 and ELT-6 function downstream of Wnt signaling to maintain the progenitor fate during larval asymmetric divisions of the seam cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

FOXOs: signalling integrators for homeostasis maintenance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Reactive oxygen species and Wnt signalling crosstalk patterns mouse extraembryonic endoderm.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The metabolic footprint of aging in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Mitochondrial oxidative stress and mammalian healthspan

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Redox regulation of Wnt signalling via nucleoredoxin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

When a theory of aging ages badly.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Should I stay or should I go: beta-catenin decides under stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Wnt signaling pathways meet Rho GTPases.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Transcriptional (dys)regulation and aging in Caenorhabditis elegans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Alternative wnt signaling is initiated by distinct receptors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The mitochondrial free radical theory of ageing--where do we stand?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Which way does the Wnt blow? Exploring the duality of canonical Wnt signaling on cellular aging.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Remarkable longevity and stress resistance of nematode PI3K-null mutants

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The common biology of cancer and ageing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Biological aging is no longer an unsolved problem

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Radical medicine: treating ageing to cure disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Evolutionary and mechanistic theories of aging.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Mechanisms of ageing: public or private?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Evolution of lifespan in C. elegans.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

The evolution of ageing and longevity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

A dual role of the Wnt signaling pathway during aging in Caenorhabditis elegans

31 May 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS8080073

The effect of dichloroacetate on health- and lifespan in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS8080073

Nothing in Biology Makes Sense except in the Light of Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS8080073

Pleiotropy, Natural Selection, and the Evolution of Senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS8080073

Longevity mutants do not establish any "new science" of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS8080073

Reduced insulin/IGF-1 signalling and human longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS8080073

ceh-16/engrailed patterns the embryonic epidermis of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS8080073

Hamilton's forces of natural selection after forty years

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS8080073

Cell fates and fusion in the C. elegans vulval primordium are regulated by the EGL-18 and ELT-6 GATA factors -- apparent direct targets of the LIN-39 Hox protein.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4999782

Anti-ageing pill pushed as bona fide drug

28 November 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS8080073

Understanding ageing from an evolutionary perspective

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27490570

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

THE EFFECT OF RETARDATION OF GROWTH UPON THE BREEDING PERIOD AND DURATION OF LIFE OF RATS

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27490570

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fitness cost of extended lifespan in Caenorhabditis elegans

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27490570

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/CANCERS8080073

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27490570%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27490570%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

27490570

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27490570%20AND%20SRC:MED&resulttype=core&format=json