Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation (Q24814522)

22 June 2017

title

Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation (English)

1 reference

22 June 2017

Levent Sari

1 reference

22 June 2017

Ioan Andricioaei

series ordinal

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22 June 2017

language of work or name

English

0 references

publication date

27 November 2005

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22 June 2017

published in

Nucleic Acids Research

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22 June 2017

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22 June 2017

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22 June 2017

page(s)

6621-6634

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DNA topoisomerases: structure, function, and mechanism

22 June 2017

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28 September 2017

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30 May 2018

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30 May 2018

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Interaction between DNA and an Escherichia coli protein omega

30 May 2018

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30 May 2018

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Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB.

30 May 2018

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28 November 2018

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Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding

28 November 2018

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Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB.

28 November 2018

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Thermophilic topoisomerase I on a single DNA molecule

28 November 2018

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19F NMR studies of vaccinia type IB topoisomerase. Conformational dynamics of the bound DNA substrate

28 November 2018

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28 November 2018

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Residues within the N-terminal Domain of Human Topoisomerase I Play a Direct Role in Relaxation*

28 November 2018

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Positive torsional strain causes the formation of a four-way junction at replication forks

28 November 2018

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Diversity of DNA topoisomerases I and inhibitors

28 November 2018

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Covalent DNA binding by vaccinia topoisomerase results in unpairing of the thymine base 5' of the scissile bond.

28 November 2018

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The conformation of constitutive DNA interaction sites for eukaryotic DNA topoisomerase I on intrinsically curved DNAs

28 November 2018

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12 December 2020

Purification of a DNA topoisomerase II from the hyperthermophilic archaeon Sulfolobus shibatae. A thermostable enzyme with both bacterial and eucaryal features

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12 December 2020

Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation

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12 December 2020

Bacterial DNA topoisomerase I can relax positively supercoiled DNA containing a single-stranded loop

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12 December 2020

Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumor drug camptothecin

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12 December 2020

Regulation of the function of eukaryotic DNA topoisomerase I: analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKI935

1 reference

22 June 2017

0 references

1 reference