Pentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translation (Q24649611)

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English	Pentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translation	scientific article

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instance of

scholarly article

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title

Pentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translation (English)

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main subject

hydrophobicity

1 reference

based on heuristic

inferred from title

pentamidine

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based on heuristic

inferred from title

author name string

Tao Sun

series ordinal

1

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Yi Zhang

series ordinal

2

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language of work or name

English

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publication date

March 2008

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published in

Nucleic Acids Research

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volume

36

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issue

5

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page(s)

1654-64

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cites work

A peripheral element assembles the compact core structure essential for group I intron self-splicing.

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Concerted folding of a Candida ribozyme into the catalytically active structure posterior to a rapid RNA compaction

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Ribosomal Crystallography: Initiation, Peptide Bond Formation, and Amino Acid Polymerization are Hampered by Antibiotics

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Aminoglycoside binding displaces a divalent metal ion in a tRNA-neomycin B complex

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Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

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7 April 2017

Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA

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7 April 2017

Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

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7 April 2017

Crystal structure of d(CGCGAATTCGCG) complexed with propamidine, a short-chain homologue of the drug pentamidine

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7 April 2017

Pentamidine is an inhibitor of PRL phosphatases with anticancer activity

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7 April 2017

Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia

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7 April 2017

Pentamidine-Associated Nephrotoxicity and Hyperkalemia in Patients with Aids

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PubMed Central

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7 April 2017

Inhibition of topoisomerases from Pneumocystis carinii by aromatic dicationic molecules

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7 April 2017

Compilation of tRNA sequences and sequences of tRNA genes

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PubMed Central

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7 April 2017

Pentamidine is an antiparasitic and apoptotic drug that selectively modifies ubiquitin.

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PubMed Central

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28 September 2017

Diamidines as antitrypanosomal, antileishmanial and antimalarial agents.

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PubMed Central

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28 September 2017

Characterization of farnesylated protein tyrosine phosphatase TcPRL-1 from Trypanosoma cruzi

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PubMed Central

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28 September 2017

Improving on nature: antibiotics that target the ribosome

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PubMed Central

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28 September 2017

DNA minor groove binders as potential antitumor and antimicrobial agents

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PubMed Central

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28 September 2017

Chemotherapy of human African trypanosomiasis: current and future prospects

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PubMed Central

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28 September 2017

Tertiary structure base pairs between D- and TpsiC-loops of Escherichia coli tRNA(Leu) play important roles in both aminoacylation and editing

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28 September 2017

Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

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28 September 2017

Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion.

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PubMed Central

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28 September 2017

Pentamidine inhibits catalytic activity of group I intron Ca.LSU by altering RNA folding.

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PubMed Central

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28 September 2017

Binding of tobramycin leads to conformational changes in yeast tRNA(Asp) and inhibition of aminoacylation

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PubMed Central

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28 September 2017

Pentamidine inhibits mitochondrial intron splicing and translation in Saccharomyces cerevisiae.

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28 September 2017

Pentamidine inhibition of group I intron splicing in Candida albicans correlates with growth inhibition

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PubMed Central

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28 September 2017

Aminoglycoside-RNA interactions

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PubMed Central

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28 September 2017

Synthetic DNA minor groove-binding drugs

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28 September 2017

AT selectivity and DNA minor groove binding: modelling, NMR and structural studies of the interactions of propamidine and pentamidine with d(CGCGAATTCGCG)2.

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28 September 2017

Variation and in vitro splicing of group I introns in rRNA genes of Pneumocystis carinii

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PubMed Central

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28 September 2017

Pathogenesis and host response in Pneumocystis carinii pneumonia

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PubMed Central

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28 September 2017

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei

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28 September 2017

Present status of chemotherapy and chemopropylaxis of human trypanosomiasis in the Eastern Hemisphere

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28 September 2017

Pentamidine isethionate. A review of its antiprotozoal activity, pharmacokinetic properties and therapeutic use in Pneumocystis carinii pneumonia

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28 September 2017

Visceral leishmaniasis unresponsive to antimonial drugs. II. Response to high dosage sodium stibogluconate or prolonged treatment with pentamidine

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28 September 2017

Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs

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28 September 2017

Early events in hepatitis C virus infection of chimpanzees.

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28 September 2017

Crystal structure of a pentamidine-oligonucleotide complex: implications for DNA-binding properties

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28 September 2017

Interaction between aromatic diamidines and nucleic acids: possible implications for chemotherapy

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28 September 2017

Purpuromycin: an antibiotic inhibiting tRNA aminoacylation

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30 May 2018

Inhibition of topoisomerases in African trypanosomes

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PubMed Central

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30 May 2018

Nephrotoxicity and hyperkalemia in patients with acquired immunodeficiency syndrome treated with pentamidine

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30 May 2018

Effect of the antibiotic purpuromycin on cell-free protein-synthesizing systems

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30 May 2018

Mechanism of action of purpuromycin

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30 May 2018

The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation

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28 November 2018

Compaction of a bacterial group I ribozyme coincides with the assembly of core helices

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28 November 2018

An evaluation of the mechanism of action of pentamidine isethionate

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28 November 2018

Pentamidine: a review

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28 November 2018

Effect of pentamidine isethionate on the ultrastructure and morphology of Leishmania mexicana amazonensis in vitro

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12 December 2020

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The ultrastructural changes of Leishmania tropica after treatment with pentamidine

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CP1 domain in Escherichia coli leucyl-tRNA synthetase is crucial for its editing function

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18263620

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The in vitro trypanocidal activity of N-substituted p-benzoquinone imines: assessment of biochemical structure-activity relationships using the Hansch approach

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18263620

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 S rRNA

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18263620

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Footprinting studies on the sequence-selective binding of pentamidine to DNA

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18263620

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of binding interactions by isothermal titration calorimetry

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18263620

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of in vitro splicing of a group I intron of Pneumocystis carinii

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18263620

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overproduction and purification ofEscherichia coli tRNA(Leu).

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1093%2FNAR%2FGKM1180

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

DOI

10.1093/NAR/GKM1180

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1380403

OpenCitations bibliographic resource ID

1380403

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1380403

PMC publication ID

2275129

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1380403

PubMed publication ID

18263620

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1380403

ResearchGate publication ID

5587778

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