Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro (Q24634078)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858438%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro (English)

1 reference

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5 March 2020

0 references

1 reference

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5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858438%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858438%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Jennifer Niven

1 reference

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5 March 2020

Nigel H Greig

series ordinal

1 reference

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5 March 2020

William Douglas Figg

series ordinal

1 reference

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5 March 2020

language of work or name

English

0 references

publication date

15 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858438%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

5 March 2020

published in

1 reference

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5 March 2020

volume

110

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5 March 2020

issue

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5 March 2020

page(s)

12703-12708

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Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

5 March 2020

cites work

1 reference

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Identification of a primary target of thalidomide teratogenicity

7 April 2017

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Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation

7 April 2017

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VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm

7 April 2017

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In vivo imaging of embryonic vascular development using transgenic zebrafish

7 April 2017

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Recognition of the phenotype of thalidomide embryopathy in countries endemic for leprosy: new cases and review of the main dysmorphological findings

7 April 2017

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Immunomodulatory drugs in multiple myeloma

27 September 2017

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Novel immunomodulatory compounds in multiple myeloma

27 September 2017

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Phase 1 study of pomalidomide MTD, safety, and efficacy in patients with refractory multiple myeloma who have received lenalidomide and bortezomib

27 September 2017

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Isosteric analogs of lenalidomide and pomalidomide: synthesis and biological activity

27 September 2017

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Nitric oxide rescues thalidomide mediated teratogenicity

27 September 2017

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Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells

27 September 2017

1 reference

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Antiangiogenic therapeutic approaches in multiple myeloma

27 September 2017

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Management of treatment-emergent peripheral neuropathy in multiple myeloma.

27 September 2017

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The clinical safety of lenalidomide in multiple myeloma and myelodysplastic syndromes

27 September 2017

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27 September 2017

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Axon guidance molecules in vascular patterning

27 September 2017

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Thalidomide-induced limb defects: resolving a 50-year-old puzzle

27 September 2017

1 reference

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Fetal malformations and early embryonic gene expression response in cynomolgus monkeys maternally exposed to thalidomide

27 September 2017

1 reference

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Pomalidomide (CC4047) plus low-dose dexamethasone as therapy for relapsed multiple myeloma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732931

The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions

27 September 2017

1 reference

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Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732931

A transgenic zebrafish model of neutrophilic inflammation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732931

Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732931

Advances in understanding drug-induced neuropathies

27 September 2017

1 reference

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Thalidomide and its analogues inhibit lipopolysaccharide-mediated Iinduction of cyclooxygenase-2.

27 September 2017

1 reference

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Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production

27 September 2017

1 reference

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Recognition of thalidomide defects

27 September 2017

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Peripheral neuropathy in multiple myeloma patients receiving lenalidomide, bortezomib, and dexamethasone (RVD) therapy

27 September 2017

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Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation

30 May 2018

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30 May 2018

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Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapsed or refractory multiple myeloma

21 January 2018

1 reference

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Thalidomide-induced antiangiogenic action is mediated by ceramide through depletion of VEGF receptors, and is antagonized by sphingosine-1-phosphate

21 January 2018

1 reference

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Absorption, metabolism and excretion of [14C]pomalidomide in humans following oral administration

21 January 2018

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Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitro

21 January 2018

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21 January 2018

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New cases of thalidomide embryopathy in Brazil

21 January 2018

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Thalidomide-based TNF-alpha inhibitors for neurodegenerative diseases

21 January 2018

1 reference

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28 November 2018

Thalidomide embryopathy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23858438

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptional inhibitor of cyclooxygenase 2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23858438

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evaluation of the developmental toxicity of lenalidomide in rabbits

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23858438

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1307684110

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858438%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

ADS bibcode

2013PNAS..11012703M

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858438%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

23858438

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858438%20AND%20SRC:MED&resulttype=core&format=json