Purification, molecular cloning, and expression of the mammalian sigma1-binding site (Q24619317)

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F F Moebius

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A Flandorfer

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H G Knaus

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J Striessnig

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E Kempner

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H Glossmann

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

23 July 1996

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published in

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volume

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issue

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page(s)

8072-7

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cites work

Phenylalkylamine Ca2+ antagonist binding protein. Molecular cloning, tissue distribution, and heterologous expression

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A simple method for displaying the hydropathic character of a protein

7 April 2017

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The psychotomimetic effects of opiates and the sigma receptor

7 April 2017

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The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog

7 April 2017

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Isolation of the gene for murine glucose-6-phosphatase, the enzyme deficient in glycogen storage disease type 1A

7 April 2017

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 April 2017

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Epitope tagging and protein surveillance

7 April 2017

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Selective reduction of N-methyl-D-aspartate-evoked responses by 1,3-di(2-tolyl)guanidine in mouse and rat cultured hippocampal pyramidal neurones

7 April 2017

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An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum

27 September 2017

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Isolation of the ERG2 gene, encoding sterol delta 8-->delta 7 isomerase, from the rice blast fungus Magnaporthe grisea and its expression in the maize smut pathogen Ustilago maydis

27 September 2017

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The effects of sigma ligands and of neuropeptide Y on N-methyl-D-aspartate-induced neuronal activation of CA3 dorsal hippocampus neurones are differentially affected by pertussin toxin

27 September 2017

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PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice

27 September 2017

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Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus

27 September 2017

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Sigma receptors: biology and function

27 September 2017

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Sterol biosynthesis inhibitors: Their current status and modes of action

27 September 2017

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Sigma receptors. Putative links between nervous, endocrine and immune systems

27 September 2017

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Radiation inactivation analysis of rat liver microsomal glucose-6-phosphatase

27 September 2017

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Subcellular localization of the enzymes of cholesterol biosynthesis and metabolism in rat liver

27 September 2017

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Biochemical characterization of a 22-kDa high affinity antiischemic drug-binding polypeptide in the endoplasmic reticulum of guinea pig liver: potential common target for antiischemic drug action.

27 September 2017

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Sterol synthesis in vivo in 18 tissues of the squirrel monkey, guinea pig, rabbit, hamster, and rat.

30 May 2018

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The lipid composition of rat brain myelin and subcellular fractions during development

30 May 2018

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Formation of methyl sterols in brain cholesterol biosynthesis. Sterol formation in vitro in actively myelinating rat brain

30 May 2018

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Molecular weight determinations from radiation inactivation

30 May 2018

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Evidence that the potential antipsychotic agent rimcazole (BW 234U) is a specific, competitive antagonist of sigma sites in brain

30 May 2018

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Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems

30 May 2018

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Functional size of acyl coenzyme A:diacylglycerol acyltransferase by radiation inactivation

30 May 2018

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Copper staining: a five-minute protein stain for sodium dodecyl sulfate-polyacrylamide gels

30 May 2018

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BMY-14802 antagonizes harmaline- and D-serine-induced increases in mouse cerebellar cyclic GMP: neurochemical evidence for a sigma receptor-mediated functional modulation of responses mediated by the N-methyl-D-aspartate receptor complex in vivo

30 May 2018

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Cloning and disruption of the yeast C-8 sterol isomerase gene

30 May 2018

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Nucleotide sequence of the gene encoding yeast C-8 sterol isomerase

30 May 2018

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Characterization of the binding of [3H](+)-pentazocine to sigma recognition sites in guinea pig brain

30 May 2018

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Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves

30 May 2018

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Polyene resistance and the isolation of sterol mutants in Saccharomyces cerevisiae.

30 May 2018

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[3H](+)-pentazocine binding to rat brain sigma 1 receptors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38877

Ameliorating effects of sigma receptor ligands on the impairment of passive avoidance tasks in mice: involvement in the central acetylcholinergic system.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38877

[Neuropeptide Y: psychopharmacological and clinical aspects]

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38877

Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38877

Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced delayed cognitive dysfunction in rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38877

Structural determinants of sigma receptor affinity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38877

Low dose of 1,3-di(2-tolyl)guanidine (DTG) attenuates MK-801-induced spatial working memory impairment in mice

28 November 2018

1 reference

12 December 2020

Altered N-methyl-D-aspartate (NMDA) activity in the mouse spinal cord following morphine is mediated by sigma activity

1 reference

12 December 2020

Sigma receptor regulation of norepinephrine release from rat hippocampal slices

1 reference

12 December 2020

Radiation inactivation reveals discrete cation binding sites that modulate dihydropyridine binding sites

1 reference

12 December 2020

3Hopipramol labels a novel binding site and sigma receptors in rat brain membranes

1 reference

12 December 2020

Pathways of enzymic synthesis and conversion to cholesterol of delta-5,7,24-cholestatrien-3 beta-ol and other naturally occurring sterols

1 reference

12 December 2020

Studies on the mechanism of the enzymatic conversion of delta 8-cholesten-3 beta-ol to delta 7-cholesten-3 beta-ol

1 reference

12 December 2020

Microsomal enzymes of cholesterol biosynthesis from lanosterol: a progress report

1 reference

12 December 2020

1 reference

12 December 2020

Calculating the dissociation constant of an unlabeled compound from the concentration required to displace radiolabel binding by 50%

1 reference

12 December 2020

Microsomal enzymes of cholesterol biosynthesis from lanosterol. Solubilization and purification of steroid 8-isomerase

1 reference

12 December 2020

Electrophysiological and binding studies on intact NCB-20 cells suggest presence of a low affinity sigma receptor

1 reference

12 December 2020

A proposal for the classification of sigma binding sites

1 reference

12 December 2020

Regulation of sigma activity by the amino-terminus of substance P in the mouse spinal cord: Involvement of phencyclidine (PCP) sites not linked to N-methyl-d-aspartate (NMDA) activity

1 reference

12 December 2020

Identification of a 27-kDa high affinity phenylalkylamine-binding polypeptide as the sigma 1 binding site by photoaffinity labeling and ligand-directed antibodies

1 reference

12 December 2020

BMY 14802, a sigma receptor ligand for the treatment of schizophrenia

1 reference

12 December 2020

Purification and amino-terminal sequencing of the high affinity phenylalkylamine Ca2+ antagonist binding protein from guinea pig liver endoplasmic reticulum

1 reference

12 December 2020

Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 site

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.93.15.8072

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ADS bibcode

1996PNAS...93.8072H

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1 reference

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PubMed publication ID

8755605

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