Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency (Q24614772)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808038%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency (English)

1 reference

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cytochrome P450 Oxidoreductase Deficiency

9 February 2020

main subject

0 references

1 reference

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9 February 2020

Chuanwu Xia

1 reference

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9 February 2020

Satya P Panda

1 reference

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9 February 2020

Christopher C Marohnic

1 reference

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9 February 2020

Bettie Sue Masters

1 reference

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9 February 2020

Jung-Ja P Kim

1 reference

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9 February 2020

language of work or name

English

0 references

publication date

1 August 2011

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

9 February 2020

number of pages

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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9 February 2020

volume

108

1 reference

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9 February 2020

issue

1 reference

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9 February 2020

page(s)

13486-13491

1 reference

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The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders

9 February 2020

cites work

1 reference

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Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis

7 April 2017

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Three-dimensional structure of NADPH–cytochrome P450 reductase: Prototype for FMN- and FAD-containing enzymes

7 April 2017

1 reference

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Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding

7 April 2017

1 reference

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Structure and Function of an NADPH-Cytochrome P450 Oxidoreductase in an Open Conformation Capable of Reducing Cytochrome P450

7 April 2017

1 reference

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NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer

7 April 2017

1 reference

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The CCP4 suite: programs for protein crystallography

7 April 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 April 2017

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7 April 2017

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Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism

22 April 2017

1 reference

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Restoration of mutant cytochrome P450 reductase activity by external flavin

7 April 2017

1 reference

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Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study

7 April 2017

1 reference

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Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome

7 April 2017

1 reference

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Association of multiple developmental defects and embryonic lethality with loss of microsomal NADPH-cytochrome P450 oxidoreductase

7 April 2017

1 reference

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Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

7 April 2017

1 reference

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Identification of Cytochrome P450 Oxidoreductase Gene Variants That Are Significantly Associated with the Interindividual Variations in Warfarin Maintenance Dose

7 April 2017

1 reference

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Human cytochrome P450 oxidoreductase deficiency caused by the Y181D mutation: molecular consequences and rescue of defect.

27 September 2017

1 reference

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Cytochrome P450 oxidoreductase deficiency: identification and characterization of biallelic mutations and genotype-phenotype correlations in 35 Japanese patients

27 September 2017

1 reference

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Cytochromes P450--a family of proteins and scientists-understanding their relationships

27 September 2017

1 reference

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Cytochromes P450, drugs, and diseases

27 September 2017

1 reference

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Identification of novel roles of the cytochrome p450 system in early embryogenesis: effects on vasculogenesis and retinoic Acid homeostasis

27 September 2017

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Trapezoidocephaly, midfacial hypoplasia and cartilage abnormalities with multiple synostoses and skeletal fractures

27 September 2017

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P450 oxidoreductase deficiency: a new disorder of steroidogenesis affecting all microsomal P450 enzymes

27 September 2017

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Diminished FAD binding in the Y459H and V492E Antley-Bixler syndrome mutants of human cytochrome P450 reductase

21 January 2018

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Impairment of human CYP1A2-mediated xenobiotic metabolism by Antley-Bixler syndrome variants of cytochrome P450 oxidoreductase.

21 January 2018

1 reference

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Modeling of human P450 oxidoreductase structure by in silico mutagenesis and MD simulation

21 January 2018

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

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Differential contributions of NADPH-cytochrome P450 oxidoreductase FAD binding site residues to flavin binding and catalysis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21808038

inferred from PubMed ID database lookup

12 December 2020

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Identifiers

DOI

10.1073/PNAS.1106632108

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808038%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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release_42nkqcftvbd37d6vzue7wrpooq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/42nkqcftvbd37d6vzue7wrpooq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808038%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

21808038

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808038%20AND%20SRC:MED&resulttype=core&format=json