The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1 (Q24562606)

19 October 2023

Kefang Xie

Kefang

Xie

1 reference

19 October 2023

Mark P Sowden

Mark P

Sowden

1 reference

19 October 2023

Geoffrey S C Dance

Geoffrey S C

Dance

1 reference

19 October 2023

Andrew T Torelli

Andrew T

Torelli

1 reference

19 October 2023

Joseph E Wedekind

Joseph E

Wedekind

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

0 references

publication date

25 May 2004

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published in

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volume

101

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issue

0 references

page(s)

8114-9

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cites work

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Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

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Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

24 March 2017

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AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization

24 March 2017

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Identification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editing

24 March 2017

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Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

24 March 2017

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Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.

24 March 2017

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Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site

24 March 2017

1 reference

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The relation between the divergence of sequence and structure in proteins

24 March 2017

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inferred from DOI database lookup

7 January 2021

based on heuristic

Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution

1 reference

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Crystal structure of the tetrameric cytidine deaminase from Bacillus subtilis at 2.0 A resolution

24 March 2017

1 reference

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Cytidine deaminase complexed to 3-deazacytidine: a "valence buffer" in zinc enzyme catalysis

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Comparative protein structure modeling of genes and genomes

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Further additions to MolScript version 1.4, including reading and contouring of electron-density maps

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

24 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

24 March 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Identification of the yeast cytidine deaminase CDD1 as an orphan C-->U RNA editase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Tissue-specific inhibition of apolipoprotein B mRNA editing in the liver by adenovirus-mediated transfer of a dominant negative mutant APOBEC-1 leads to increased low density lipoprotein in mice

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Twilight zone of protein sequence alignments

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

AID mediates hypermutation by deaminating single stranded DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Comparative analyses of immunoglobulin genes: surprises and portents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

AID is essential for immunoglobulin V gene conversion in a cultured B cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Mechanism and control of class-switch recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

RNA editing by base deamination: more enzymes, more targets, new mysteries

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

An AU-rich sequence element (UUUN[A/U]U) downstream of the edited C in apolipoprotein B mRNA is a high-affinity binding site for Apobec-1: binding of Apobec-1 to this motif in the 3' untranslated region of c-myc increases mRNA stability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Apolipoprotein B mRNA editing: the sequence to the event

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Overexpression of APOBEC-1 results in mooring sequence-dependent promiscuous RNA editing.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

The AID enzyme induces class switch recombination in fibroblasts

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=419566

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

30 May 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0400493101

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0400493101

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21 January 2018

1 reference

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Statistical modelling and phylogenetic analysis of a deaminase domain

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0400493101

Domain organization of activation-induced cytidine deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400493101

AID mutant analyses indicate requirement for class-switch-specific cofactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400493101

Multiwavelength anomalous diffraction phasing of macromolecular structures: analysis of MAD data as single isomorphous replacement with anomalous scattering data using the MADMRG Program

21 January 2018

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0400493101

0 references

ADS bibcode

2004PNAS..101.8114X

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Fatcat ID

release_7x4hyakk2ndsvpamns2iyoighy

0 references

PMC publication ID

419566

0 references