Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice (Q24564490)

blood coagulation disease

GOA release 2020-03-11

1 reference

1 reference

1 reference

1 reference

1 reference

ORCID Public Data File 2021

Lieve Moons

1 reference

ORCID Public Data File 2021

author name string

L R Jalbert

0 references

E D Rosen

0 references

L Moons

0 references

J C Chan

0 references

P Carmeliet

0 references

D Collen

0 references

F J Castellino

Journal of Clinical Investigation

0 references

language of work or name

English

0 references

publication date

15 October 1998

0 references

published in

0 references

volume

102

0 references

issue

0 references

page(s)

1481-8

0 references

cites work

A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

The nucleotide sequence of the gene for human protein C

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Mice lacking factor VII develop normally but suffer fatal perinatal bleeding

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

The protein C anticoagulant system: inherited defects as basis for venous thrombosis

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Homozygous protein C deficiency with delayed onset of symptoms at 7 to 10 months

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Developmental expression of protein C and protein S in the rat

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Characterization of a cDNA coding for human protein C

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Nucleotide sequence of the gene for human factor IX (antihemophilic factor B)

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin deficiency in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Prothrombin deficiency results in embryonic and neonatal lethality in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Dysfunctional protein C deficiency (type II). A report of 11 cases in 3 American families and review of the literature

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Preparation and properties of bovine factor VIII (antihemophilic factor).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Gene for human factor X: a blood coagulation factor whose gene organization is essentially identical with that of factor IX and protein C.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Neonatal purpura fulminans due to homozygous protein C or protein S deficiencies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Anticoagulant properties of bovine plasma protein C following activation by thrombin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

A coagulation factor IX-deficient mouse model for human hemophilia B

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Heterozygous protein C deficiency and dysfibrinogenemia acquired by liver transplantation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Characterization of a protein C activator from the venom of Agkistrodon contortrix contortrix

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

A gamma-carboxyglutamic acid (gamma) variant (gamma 6D, gamma 7D) of human activated protein C displays greatly reduced activity as an anticoagulant

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

The site of activation of factor X by cancer procoagulant

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Synthesis of Protein C in Human Umbilical Vein Endothelial Cells1

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Rapid activation of protein C by factor Xa and thrombin in the presence of polyanionic compounds.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Role of the thrombin receptor in development and evidence for a second receptor.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Severe type I protein C deficiency in a compound heterozygote for Y124C and Q132X mutations in exon 6 of the PROC gene

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508997

Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice

28 November 2018

1 reference

12 December 2020

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C

1 reference

12 December 2020

Amino acid sequence of the heavy chain of bovine protein C.

1 reference

12 December 2020

Whole blood clot lysis: in vitro modulation by activated protein C

1 reference

12 December 2020

Protein S is a cofactor for activated protein C neutralization of an inhibitor of plasminogen activation released from platelets

1 reference

12 December 2020

Inflammation and coagulation: linked processes potentially regulated through a common pathway mediated by protein C

1 reference

12 December 2020

Severe acquired protein C deficiency in purpura fulminans associated with disseminated intravascular coagulation: treatment with protein C concentrate

1 reference

12 December 2020

Non-injection methods for the production of embryonic stem cell-embryo chimaeras

1 reference

12 December 2020

Hypercoagulable states

1 reference

12 December 2020

Hereditary thrombophilia among 217 consecutive patients with thromboembolic disease in Jordan

1 reference

12 December 2020

Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN-gamma, or phorbol ester

1 reference

12 December 2020

An antifibrinolytic mechanism describing the prothrombotic effect associated with factor VLeiden

1 reference

12 December 2020

The gene encoding vitamin K-dependent anticoagulant protein C is expressed in human male reproductive tissues

1 reference

12 December 2020

Nucleotide structure and characterization of the murine gene encoding anticoagulant protein C

1 reference

12 December 2020