Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesity (Q24337677)

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English	Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesity	scientific article

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scholarly article

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Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesity (English)

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GOA release 2020-03-11

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based on heuristic

inferred from title

9

object named as

Paul D Berk

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author name string

José L Walewski

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Fengxia Ge

2

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Harrison Lobdell

3

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Nancy Levin

4

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Gary J Schwartz

5

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Joseph R Vasselli

6

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Afons Pomp

7

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Gregory Dakin

8

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publication date

July 2014

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22

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7

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1643-52

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Medical Consequences of Obesity

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Evolutionary sequence modeling for discovery of peptide hormones

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19 March 2017

Peptides derived from the prohormone proNPQ/spexin are potent central modulators of cardiovascular and renal function and nociception

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19 March 2017

Spexin expression in normal rat tissues

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077920

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Serum immunoreactive-leptin concentrations in normal-weight and obese humans

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Targeted loss of GHR signaling in mouse skeletal muscle protects against high-fat diet-induced metabolic deterioration

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27 September 2017

Intracerebroventricular Leptin Infusion Improves Glucose Homeostasis in Lean Type 2 Diabetic MKR Mice via Hepatic Vagal and Non-Vagal Mechanisms

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Region-Specific Involvement of BDNF Secretion and Synthesis in Conditioned Taste Aversion Memory Formation

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Experience with activity based anorexia enhances conditioned taste aversion learning in rats

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27 September 2017

Adipocyte accumulation of long-chain fatty acids in obesity is multifactorial, resulting from increased fatty acid uptake and decreased activity of genes involved in fat utilization

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27 September 2017

Adipokines as novel modulators of lipid metabolism.

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Tenomodulin is highly expressed in adipose tissue, increased in obesity, and down-regulated during diet-induced weight loss

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27 September 2017

Regulatable fatty acid transport mechanisms are central to the pathophysiology of obesity, fatty liver, and metabolic syndrome

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27 September 2017

Obesity, weight management, and health care costs: a primer

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27 September 2017

Tenomodulin is associated with obesity and diabetes risk: the Finnish diabetes prevention study

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27 September 2017

Identification of novel peptide hormones in the human proteome by hidden Markov model screening.

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A potential decline in life expectancy in the United States in the 21st century

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27 September 2017

Leptin and insulin modulate nutrient partitioning and weight loss in ob/ob mice through regulation of long-chain fatty acid uptake by adipocytes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077920

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A mechanism for hormesis--a problem in the wrong discipline

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Annual Deaths Attributable to Obesity in the United States

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27 September 2017

Selective up-regulation of fatty acid uptake by adipocytes characterizes both genetic and diet-induced obesity in rodents.

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27 September 2017

At physiologic albumin/oleate concentrations oleate uptake by isolated hepatocytes, cardiac myocytes, and adipocytes is a saturable function of the unbound oleate concentration. Uptake kinetics are consistent with the conventional theory

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27 September 2017

Goldfish spexin: solution structure and novel function as a satiety factor in feeding control.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077920

30 May 2018

Expression of the spexin gene in the rat adrenal gland and evidences suggesting that spexin inhibits adrenocortical cell proliferation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077920

30 May 2018

Macrophage chitinase 1 stratifies chronic obstructive lung disease

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30 May 2018

Long-chain fatty acid uptake is upregulated in omental adipocytes from patients undergoing bariatric surgery for obesity.

1 reference

https://api.crossref.org/works/10.1002%2FOBY.20725

21 January 2018

Monoclonal antibody antagonists of hypothalamic FGFR1 cause potent but reversible hypophagia and weight loss in rodents and monkeys

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https://api.crossref.org/works/10.1002%2FOBY.20725

21 January 2018

Hormetic effect of amyloid-β peptide in synaptic plasticity and memory.

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21 January 2018

A novel neuropeptide in suppressing luteinizing hormone release in goldfish, Carassius auratus.

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https://api.crossref.org/works/10.1002%2FOBY.20725

21 January 2018

Spexin is expressed in the carotid body and is upregulated by postnatal hyperoxia exposure.

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21 January 2018

Oleic acid uptake and binding by rat adipocytes define dual pathways for cellular fatty acid uptake

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12 December 2020

based on heuristic

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Analysis of long-chain free fatty acid binding to bovine serum albumin by determination of stepwise equilibrium constants

1 reference

https://pubmed.ncbi.nlm.nih.gov/24550067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1002/OBY.20725

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