Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes (Q24336203)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

TERF1 interacting nuclear factor 2

6 January 2020

main subject

cell biology

0 references

1 reference

protein localization to chromosome, telomeric region

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Sahn-Ho Kim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Albert R Davalos

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Seok-Jin Heo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Ying Zou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Christian Beausejour

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Patrick Kaminker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Steven M Yannone

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

language of work or name

English

0 references

publication date

28 April 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

181

1 reference

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6 January 2020

issue

1 reference

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6 January 2020

page(s)

447-460

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase

6 January 2020

cites work

1 reference

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A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly

19 March 2017

1 reference

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POT1 and TRF2 cooperate to maintain telomeric integrity

19 March 2017

1 reference

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Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins

19 March 2017

1 reference

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A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2

19 March 2017

1 reference

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POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex

19 March 2017

1 reference

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PTOP interacts with POT1 and regulates its localization to telomeres

19 March 2017

1 reference

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Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

19 March 2017

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The human telomere-associated protein TIN2 stimulates interactions between telomeric DNA tracts in vitro

19 March 2017

1 reference

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POT1 as a terminal transducer of TRF1 telomere length control

19 March 2017

1 reference

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Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicing

19 March 2017

1 reference

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TIN2, a new regulator of telomere length in human cells

19 March 2017

1 reference

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Mammalian telomeres end in a large duplex loop

19 March 2017

1 reference

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Control of telomere length by the human telomeric protein TRF1

19 March 2017

1 reference

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

19 March 2017

1 reference

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A system for stable expression of short interfering RNAs in mammalian cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

TRF2 Protects Human Telomeres from End-to-End Fusions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Shelterin: the protein complex that shapes and safeguards human telomeres

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

TIN2 mediates functions of TRF2 at human telomeres

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Pot1, the putative telomere end-binding protein in fission yeast and humans

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Regulation of telomerase by telomeric proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

A DNA damage checkpoint response in telomere-initiated senescence

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

DNA damage foci at dysfunctional telomeres

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

A third-generation lentivirus vector with a conditional packaging system

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

7 April 2017

https://api.crossref.org/works/10.1083%2FJCB.200710028

inferred from DOI database lookup

7 January 2021

based on heuristic

Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Inhibition of p53 by lentiviral mediated shRNA abrogates G1 arrest and apoptosis in retinal pigmented epithelial cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Cancer and aging: the importance of telomeres in genome maintenance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Does a sentinel or a subset of short telomeres determine replicative senescence?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Reversal of human cellular senescence: roles of the p53 and p16 pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Different telomere damage signaling pathways in human and mouse cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

TRF1 binds a bipartite telomeric site with extreme spatial flexibility

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Telomere analysis by fluorescence in situ hybridization and flow cytometry

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Isolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNA

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364703

Telomere states and cell fates

27 September 2017

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710028

Inhibition of telomerase limits the growth of human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710028

Importance of TRF1 for Functional Telomere Structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710028

Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710028

Caspase-independent cytochrome c release is a sensitive measure of low-level apoptosis in cell culture models

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18443218

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Limited capacity of the nuclear matrix to bind telomere repeat binding factor TRF1 may restrict the proliferation of mortal human fibroblasts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18443218

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200710028

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

18443218

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18443218%20AND%20SRC:MED&resulttype=core&format=json