Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP (Q24311629)

neurotransmitter metabolic process

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

S Milstien

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H Jaffe

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D Kowlessur

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T I Bonner

Journal of Biological Chemistry

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language of work or name

English

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publication date

16 August 1996

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published in

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volume

271

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issue

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page(s)

19743-51

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cites work

GTP cyclohydrolase I deficiency, a new enzyme defect causing hyperphenylalaninemia with neopterin, biopterin, dopamine, and serotonin deficiencies and muscular hypotonia.

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Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene

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Endocrine-dependent regulation of tetrahydrobiopterin levels and guanosine triphosphate cyclohydrolase activity

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Tetrahydrobiopterin increases in adrenal medulla and cortex: a factor in the regulation of tyrosine hydroxylase

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Tetrahydrobiopterin cofactor biosynthesis: GTP cyclohydrolase I mRNA expression in rat brain and superior cervical ganglia

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Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity

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Biopterin derivatives in normal and phenylketonuric patients after oral loads of L-phenylalanine, L-tyrosine, and L-tryptophan

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Feedback regulation mechanisms for the control of GTP cyclohydrolase I activity

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The application of 8-aminoguanosine triphosphate, a new inhibitor of GTP cyclohydrolase I, to the purification of the enzyme from human liver

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Human GTP cyclohydrolase I: only one out of three cDNA isoforms gives rise to the active enzyme

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Guanosine triphosphate cyclohydrolase activity in rat tissues

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Induction of GTP-cyclohydrolase I mRNA expression by lectin activation and interferon-gamma treatment in human cells associated with the immune response

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GTP Cyclohydrolase I mRNA Is Induced by LPS in Vascular Smooth Muscle: Characterization, Sequence and Relationship to Nitric Oxide Synthase

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Growth Factor Regulation of Interleukin-1β-Induced Nitric Oxide Synthase and GTP: Cyclohydrolase Expression in Cultured Smooth Muscle Cells

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Internal protein sequence analysis: enzymatic digestion for less than 10 micrograms of protein bound to polyvinylidene difluoride or nitrocellulose membranes

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Synthesis of enzymatically active D-7,8-dihydroneopterin-3′-triphosphate

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Hormonal Regulation of Guanosine Triphosphate Cyclohydrolase Activity and Biopterin Levels in the Rat Adrenal Cortex

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