Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells (Q24309588)

Growth differentiation factor 2

1 reference

Bone morphogenetic protein 10

1 reference

endoglin

1 reference

pathway-restricted SMAD protein phosphorylation

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Distribution of ENG and ACVRL1 (ALK1) mutations in French HHT patients

Laurent David

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Jean-Jacques Feige

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Christine Mallet

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Sabine Mazerbourg

series ordinal

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Sabine Bailly

series ordinal

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language of work or name

English

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publication date

1 March 2007

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published in

Blood

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volume

109

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issue

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page(s)

1953-61

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cites work

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I. receptors

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Distinct regulation of gene expression in human endothelial cells by TGF-beta and its receptors

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Arteriovenous malformations in mice lacking activin receptor-like kinase-1

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

An integrated functional genomics screening program reveals a role for BMP-9 in glucose homeostasis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Bone morphogenetic protein 9 is a potent synergistic factor for murine hemopoietic progenitor cell generation and colony formation in serum-free cultures

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Bone morphogenetic protein-9. An autocrine/paracrine cytokine in the liver

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Crystal structure of BMP-9 and functional interactions with pro-region and receptors

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Endoglin structure and function: Determinants of endoglin phosphorylation by transforming growth factor-beta receptors

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Analysis of ALK-1 and endoglin in newborns from families with hereditary hemorrhagic telangiectasia type 2.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Vascular morphogenesis: tales of two syndromes.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Characterization of type I receptors for transforming growth factor-beta and activin

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Genotype-phenotype relationship in hereditary haemorrhagic telangiectasia.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

SMAD4 mutations found in unselected HHT patients.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Smad7 and protein phosphatase 1alpha are critical determinants in the duration of TGF-beta/ALK1 signaling in endothelial cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021

BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2006-07-034124

7 January 2021