Crystal structure of a lipid G protein-coupled receptor (Q24305457)

sphingosine-1-phosphate receptor activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Raymond C Stevens

0 references

Michael A Hanson

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Christopher B Roth

0 references

Euijung Jo

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Mark T Griffith

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Fiona L Scott

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Greg Reinhart

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Hans Desale

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Bryan Clemons

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Stuart M Cahalan

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Stephan C Schuerer

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M Germana Sanna

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Gye Won Han

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Peter Kuhn

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Hugh Rosen

Crystal structure of the β2 adrenergic receptor-Gs protein complex

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language of work or name

English

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publication date

17 February 2012

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published in

Science

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volume

335

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issue

6070

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page(s)

851-5

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cites work

1 reference

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

19 March 2017

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Structure of an agonist-bound human A2A adenosine receptor

19 March 2017

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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

19 March 2017

1 reference

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

19 March 2017

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

19 March 2017

1 reference

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

19 March 2017

1 reference

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Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

19 March 2017

1 reference

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Structure of a beta1-adrenergic G-protein-coupled receptor

19 March 2017

1 reference

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Crystal structure of the ligand-free G-protein-coupled receptor opsin

19 March 2017

1 reference

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Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

19 March 2017

2 references

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19 March 2017

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Crystal structure of rhodopsin: A G protein-coupled receptor

6 April 2017

1 reference

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A ligand channel through the G protein coupled receptor opsin

19 March 2017

1 reference

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International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature

19 March 2017

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Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions

19 March 2017

1 reference

Crossref

https://api.crossref.org/works/10.1126/SCIENCE.1215904

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

22 April 2017

1 reference

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Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

7 April 2017

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A lipid pathway for ligand binding is necessary for a cannabinoid G protein-coupled receptor

27 September 2017

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Sphingosine 1-phosphate receptor signaling

27 September 2017

1 reference

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Discovery of new GPCR biology: one receptor structure at a time

27 September 2017

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Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening

27 September 2017

1 reference

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Identification of the hydrophobic ligand binding pocket of the S1P1 receptor

27 September 2017

1 reference

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Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

27 September 2017

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Novel procedure for modeling ligand/receptor induced fit effects.

27 September 2017

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S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate

27 September 2017

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Sphingosine 1-phosphate analogs as receptor antagonists

27 September 2017

1 reference

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Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin

27 September 2017

1 reference

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G protein-coupled receptor rhodopsin: a prospectus

27 September 2017

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A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors

27 September 2017

1 reference

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Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate.

27 September 2017

1 reference

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Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes.

27 September 2017

1 reference

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Accurate prediction of the relative potencies of members of a series of kinase inhibitors using molecular docking and MM-GBSA scoring

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22344443

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1215904

1 reference

1 reference

1 reference

PubMed publication ID

22344443

1 reference