The inhibitory receptor LILRB1 modulates the differentiation and regulatory potential of human dendritic cells (Q24304323)

negative regulation of transforming growth factor beta production

GOA release 2020-03-11

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1 reference

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Neil T Young

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Edward C P Waller

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Rashmi Patel

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Ali Roghanian

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Jonathan M Austyn

Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells.

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language of work or name

English

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publication date

15 March 2008

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published in

Blood

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volume

111

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issue

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page(s)

3090-6

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cites work

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HLA-G inhibits the functions of murine dendritic cells via the PIR-B immune inhibitory receptor

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Interleukin 10 regulates cell surface and soluble LIR-2 (CD85d) expression on dendritic cells resulting in T cell hyporesponsiveness in vitro

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A gene signature of inhibitory MHC receptors identifies a BDCA3(+) subset of IL-10-induced dendritic cells with reduced allostimulatory capacity in vitro

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p40/LAIR-1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte-monocyte colony-stimulating factor

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The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes

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Recruitment of C-terminal Src kinase by the leukocyte inhibitory receptor CD85j.

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CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions

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B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse

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Different faces of regulatory DCs in homeostasis and immunity

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Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells

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The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18.

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The interaction properties of costimulatory molecules revisited.

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Blood monocytes consist of two principal subsets with distinct migratory properties

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Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

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Dendritic cells and the control of immunity

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Exacerbated graft-versus-host disease in Pirb-/- mice

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Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4

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Impaired dendritic cell maturation and increased T(H)2 responses in PIR-B(-/-) mice

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Plasticity in the organization and sequences of human KIR/ILT gene families

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

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A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells

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Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

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Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation

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CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

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Modulation of TLR signalling by the C-terminal Src kinase (Csk) in macrophages

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Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens

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Tolerogenic dendritic cells

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Fc receptor gamma-chain activation via hOSCAR induces survival and maturation of dendritic cells and modulates Toll-like receptor responses

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Human cytomegalovirus-derived protein UL18 alters the phenotype and function of monocyte-derived dendritic cells

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Ig-like transcript 2 (ILT2)/leukocyte Ig-like receptor 1 (LIR1) inhibits TCR signaling and actin cytoskeleton reorganization.

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CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells

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CD85j (leukocyte Ig-like receptor-1/Ig-like transcript 2) inhibits human osteoclast-associated receptor-mediated activation of human dendritic cells

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Recombinant Ig-like transcript 3-Fc modulates T cell responses via induction of Th anergy and differentiation of CD8+ T suppressor cells

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