Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP (Q24298571)

TEA domain family member 1

GOA release 2020-03-11

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GOA release 2020-03-11

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6 June 2020

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6 June 2020

Fa-Xing Yu

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6 June 2020

Jung-Soon Mo

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Guangbo Liu

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Young Chul Kim

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Zhipeng Meng

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6 June 2020

Ling Zhao

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6 June 2020

Gholam Peyman

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6 June 2020

Hong Ouyang

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6 June 2020

Wei Jiang

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6 June 2020

Jiagang Zhao

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6 June 2020

Xu Chen

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6 June 2020

Liangfang Zhang

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6 June 2020

Cun-Yu Wang

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6 June 2020

Kang Zhang

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6 June 2020

Kun-Liang Guan

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6 June 2020

language of work or name

English

0 references

publication date

16 June 2014

0 references

published in

Cancer Cell

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6 June 2020

volume

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issue

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6 June 2020

page(s)

822-830

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Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

6 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Mutations in GNA11 in uveal melanoma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The Hippo Signaling Pathway in Development and Cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Expression of Yes-associated protein in common solid tumors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

TEAD mediates YAP-dependent gene induction and growth control

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ

19 March 2017

1 reference

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Improved discrimination of melanotic schwannoma from melanocytic lesions by combined morphological and GNAQ mutational analysis.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The T1799A BRAF mutation is present in iris melanoma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The emerging role of lysophosphatidic acid in cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer.

27 September 2017

1 reference

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The Hippo pathway and human cancer.

27 September 2017

1 reference

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The Hippo pathway: regulators and regulations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFβ-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Genetic and molecular characterization of uveal melanoma cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Hippo signaling: growth control and beyond

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Mutational profile of GNAQQ209 in human tumors.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

YAP regulates neural progenitor cell number via the TEA domain transcription factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Uveal melanoma: epidemiologic aspects

27 September 2017

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Photodynamic therapy with verteporfin (Visudyne): impact on ophthalmology and visual sciences.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The Hippo pathway--from top to bottom and everything in between.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075337

The neural crest origin of uveal melanomas

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24882516

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Collaborative Ocular Melanoma Study (COMS) randomized trial of pre-enucleation radiation of large choroidal melanoma II: initial mortality findings COMS report no. 10

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24882516

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CCR.2014.04.017

2 references

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6 June 2020

1 reference

2 references

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6 June 2020

PubMed publication ID

24882516

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24882516%20AND%20SRC:MED&resulttype=core&format=json