A Product of the Human Gene Adjacent to parkin Is a Component of Lewy Bodies and Suppresses Pael Receptor-induced Cell Death (Q24297163)

https://api.crossref.org/works/10.1074/JBC.M309655200

19 March 2024

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negative regulation of cell death

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Parkin RBR E3 ubiquitin protein ligase

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PARK2 co-regulated

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https://api.crossref.org/works/10.1074/JBC.M309655200

19 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M309655200

19 March 2024

Mikio Shoji

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14532270

19 March 2024

author name string

Yuzuru Imai

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Mariko Soda

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Tetsuro Murakami

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Koji Abe

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Ryosuke Takahashi

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language of work or name

English

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publication date

19 December 2003

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7 October 2003

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14532270

full work available at URL

19 March 2024

http://www.jbc.org/article/S002192582075458X/pdf

file format

Portable Document Format

online access status

open access

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14532270

https://api.elsevier.com/content/article/PII:S002192582075458X?httpAccept=text/xml

19 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M309655200

https://api.elsevier.com/content/article/PII:S002192582075458X?httpAccept=text/plain

19 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M309655200

https://syndication.highwire.org/content/doi/10.1074/jbc.M309655200

19 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M309655200

Journal of Biological Chemistry

19 March 2024

published in

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volume

278

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issue

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page(s)

51901-10

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cites work

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease

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Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients

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Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

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Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

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The genomic structure and promoter region of the human parkin gene

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Identification of a novel gene linked to parkin via a bi-directional promoter

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An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

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CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

21 January 2018

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TCP1 complex is a molecular chaperone in tubulin biogenesis

21 January 2018

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The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo.

21 January 2018

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Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo

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A cytoplasmic chaperonin that catalyzes beta-actin folding

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21 January 2018

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Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

21 January 2018

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Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

21 January 2018

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Parkin accumulation in aggresomes due to proteasome impairment

21 January 2018

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Identification and characterization of the human parkin gene promoter

21 January 2018

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Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

21 January 2018

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Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

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Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease?

21 January 2018

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alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins

21 January 2018

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

21 January 2018

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A monomeric red fluorescent protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M309655200

Polyglutamine protein aggregates are dynamic

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309655200

inferred from DOI database lookup

7 January 2021

based on heuristic

Neurochemical and neurogenetic correlates of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1074/JBC.M309655200

19 March 2024

Identifiers

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017