Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity (Q24296667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23792957%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity (English)

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3 March 2020

0 references

1 reference

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Parkinsonism associated deglycase

1 reference

detoxification of mercury ion

GOA release 2020-03-11

1 reference

Parkinson disease (autosomal recessive, early onset) 7

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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3 March 2020

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3 March 2020

Benny Björkblom

1 reference

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3 March 2020

Altynai Adilbayeva

1 reference

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3 March 2020

Dominik Piston

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3 March 2020

Mats Ökvist

1 reference

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3 March 2020

Xiang Ming Xu

1 reference

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3 March 2020

Cato Brede

1 reference

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3 March 2020

Jan Petter Larsen

1 reference

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3 March 2020

language of work or name

English

0 references

publication date

21 June 2013

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Journal of Biological Chemistry

3 March 2020

published in

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3 March 2020

volume

288

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3 March 2020

issue

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3 March 2020

page(s)

22809-22820

1 reference

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Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage

3 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells

19 March 2017

1 reference

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Why molecules move along a temperature gradient

19 March 2017

1 reference

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Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

19 March 2017

1 reference

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Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

19 March 2017

1 reference

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

19 March 2017

1 reference

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DJ-1 has a role in antioxidative stress to prevent cell death

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Parkinson's disease and exposure to infectious agents and pesticides and the occurrence of brain injuries: role of neuroinflammation

19 March 2017

1 reference

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Transport of toxic metals by molecular mimicry

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

19 March 2017

1 reference

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Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Protein production by auto-induction in high density shaking cultures

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Staging of brain pathology related to sporadic Parkinson's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Biochemical characterization of the human copper transporter Ctr1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Parkinson disease in twins: an etiologic study

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

19 March 2017

1 reference

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Epidemiology and etiology of Parkinson's disease: a review of the evidence

19 March 2017

1 reference

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Heritability of Parkinson disease in Swedish twins: a longitudinal study

27 September 2017

1 reference

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Transition metal homeostasis: from yeast to human disease.

27 September 2017

1 reference

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Manganese-Induced Parkinsonism due to Ephedrone Abuse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Metals, oxidative stress and neurodegenerative disorders

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Human health effects of methylmercury exposure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Structural effects of Parkinson's disease linked DJ-1 mutations.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Metal-catalyzed oxidation of protein-bound dopamine.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Molecular and ionic mimicry and the transport of toxic metals.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

The relevance of iron in the pathogenesis of Parkinson's disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Differential Effects of Parkinson's Disease-associated Mutations on Stability and Folding of DJ-1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Manganese induced parkinsonism: an outbreak due to an unrepaired ventilation control system in a ferromanganese smelter.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Parkinson's disease and exposure to agricultural work and pesticide chemicals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

Epidemiologic study on the association between body burden mercury level and idiopathic Parkinson's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829365

The role of pathogenic DJ-1 mutations in Parkinson's disease.

27 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

The Arabidopsis DJ-1a protein confers stress protection through cytosolic SOD activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

Levodopa pharmacokinetics and motor performance during activities of daily living in patients with Parkinson's disease on individual drug combinations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

Soluble, highly fluorescent variants of green fluorescent protein (GFP) for use in higher plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease.

21 January 2018

1 reference

12 December 2020

All JNKs Can Kill, but Nuclear Localization Is Critical for Neuronal Death

1 reference

12 December 2020

The relevance of iron in the pathogenesis of Parkinson's disease

1 reference

12 December 2020

Parkinson's disease in a nationwide twin cohort

1 reference

12 December 2020

Organic cation transporters

1 reference

12 December 2020

Etiology and pathogenesis of Parkinson's disease

1 reference

12 December 2020

Covalent binding of catechols to proteins through the sulphydryl group

1 reference

12 December 2020

Online collection and analysis of X-ray fluorescence spectra on the macromolecular crystallography beamlines of the ESRF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.482091

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1074/JBC.M113.482091

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23792957%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23792957%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

23792957

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23792957%20AND%20SRC:MED&resulttype=core&format=json