Synaptophysin (Q14864392)

http://www.ebi.ac.uk/interpro/protein/Q62277

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Marvel domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

10 August 2016

protein domain specific binding

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

protein-containing complex binding

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

SNARE binding

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

1 reference

14 January 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

4 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

14 January 2019

Interaction assays in yeast and cultured cells confirm known and identify novel partners of the synaptic vesicle protein synaptophysin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Phosphorylation state of postsynaptic density proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

synaptic vesicle

Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells

8 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

14 January 2019

Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Glutamate Transporter GLAST Is Expressed in the Radial Glia–Astrocyte Lineage of Developing Mouse Spinal Cord

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Distinct developmental expression of synaptotagmin I and IX in the mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

SynCAM, a synaptic adhesion molecule that drives synapse assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

synapse

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

12 references

14 January 2019

14 January 2019

Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Interaction assays in yeast and cultured cells confirm known and identify novel partners of the synaptic vesicle protein synaptophysin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Synaptic protein α1-takusan mitigates amyloid-β-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

synaptic vesicle membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

3 references

16 September 2017

16 September 2017

Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

16 September 2017

Molecular determinants of synapsin targeting to presynaptic terminals

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

presynaptic active zone

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

1 reference

14 January 2019

integral component of synaptic vesicle membrane

TAS

1 reference

16 September 2017

Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

TAS

presynaptic membrane

cytoplasmic vesicle

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

1 reference

14 January 2019

neuron projection terminus

2 references

16 September 2017

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

16 September 2017

Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

neuron projection

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain

3 references

16 September 2017

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

16 September 2017

16 September 2017

LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

excitatory synapse

1 reference

16 September 2017

NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

neuromuscular junction

1 reference

14 January 2019

Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

synaptic vesicle membrane

4 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

14 January 2019

Molecular determinants of synapsin targeting to presynaptic terminals

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

protein-containing complex

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

neuron projection

5 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Ensembl genome database project

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

terminal bouton

4 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

Ensembl genome database project

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

intracellular organelle

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

neuron projection terminus

3 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

neuron spine

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

biological process

transport

1 reference

10 August 2016

regulation of neuronal synaptic plasticity

2 references

10 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

endocytosis

1 reference

10 August 2016

regulation of opioid receptor signaling pathway

1 reference

10 August 2016

endocytosis

Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons

3 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

14 January 2019

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

synaptic vesicle endocytosis

IMP

1 reference

14 January 2019

Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62277&geneProductId=UniProtKB:Q62277

1 reference

InterPro Release 71.0