Pages that link to "Q34232193"

The following pages link to A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation (Q34232193):

Displaying 37 items.

• TFP5/TP5 peptide provides neuroprotection in the MPTP model of Parkinson's disease (Q26747606) (← links)
• Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitors (Q26827580) (← links)
• Physiological and pathological phosphorylation of tau by Cdk5 (Q26860395) (← links)
• TFP5 peptide, derived from CDK5-activating cofactor p35, provides neuroprotection in early-stage of adult ischemic stroke (Q28397588) (← links)
• Anti-diabetes drug pioglitazone ameliorates synaptic defects in AD transgenic mice by inhibiting cyclin-dependent kinase5 activity (Q28546302) (← links)
• First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors. (Q33935146) (← links)
• Long- and short-term CDK5 knockdown prevents spatial memory dysfunction and tau pathology of triple transgenic Alzheimer's mice (Q34159111) (← links)
• TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice (Q34549221) (← links)
• Cdk5 inhibitory peptide (CIP) inhibits Cdk5/p25 activity induced by high glucose in pancreatic beta cells and recovers insulin secretion from p25 damage (Q34988118) (← links)
• Detection and characterization of nonspecific, sparsely populated binding modes in the early stages of complexation (Q35537330) (← links)
• p35 and Rac1 underlie the neuroprotection and cognitive improvement induced by CDK5 silencing (Q35815964) (← links)
• TFP5, a peptide derived from p35, a Cdk5 neuronal activator, rescues cortical neurons from glucose toxicity (Q36082706) (← links)
• Peptide TFP5/TP5 derived from Cdk5 activator P35 provides neuroprotection in the MPTP model of Parkinson's disease (Q36337052) (← links)
• A truncated peptide from p35, a Cdk5 activator, prevents Alzheimer's disease phenotypes in model mice (Q36482937) (← links)
• Deregulated Cdk5 activity is involved in inducing Alzheimer's disease (Q36494716) (← links)
• Tau pathology-mediated presynaptic dysfunction (Q36951523) (← links)
• Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein (Q37053942) (← links)
• Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation (Q37238059) (← links)
• Mesenchymal Stem Cells Loaded with p5, Derived from CDK5 Activator p35, Inhibit Calcium-Induced CDK5 Activation in Endothelial Cells (Q37249928) (← links)
• TFP5 prevents 1-methyl-4-phenyl pyridine ion-induced neurotoxicity in mouse cortical neurons (Q37288349) (← links)
• Computational study of the inhibitory mechanism of the kinase CDK5 hyperactivity by peptide p5 and derivation of a pharmacophore (Q37503295) (← links)
• The interaction of Munc 18 (p67) with the p10 domain of p35 protects in vivo Cdk5/p35 activity from inhibition by TFP5, a peptide derived from p35. (Q37518226) (← links)
• Special Issue on "Cdk5 and Brain Disorders": Prologue (Q37566867) (← links)
• Cdk5: Mediator of neuronal development, death and the response to DNA damage (Q37877809) (← links)
• The Role of Cdk5 in Alzheimer's Disease (Q38557958) (← links)
• Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses (Q38587949) (← links)
• Cdk5 links with DNA damage response and cancer (Q39176295) (← links)
• Neurodegeneration-Like Pathological and Behavioral Changes in an AAV9-Mediated p25 Overexpression Mouse Model (Q40720592) (← links)
• Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo. (Q45971854) (← links)
• Profiling of p5, a 24 Amino Acid Inhibitory Peptide Derived from the CDK5 Activator, p35 CDKR1 Against 70 Protein Kinases (Q51546743) (← links)
• MultiBacMam Bimolecular Fluorescence Complementation (BiFC) tool-kit identifies new small-molecule inhibitors of the CDK5-p25 protein-protein interaction (PPI). (Q52639336) (← links)
• Cdk5 Inhibitory Peptide Prevents Loss of Dopaminergic Neurons and Alleviates Behavioral Changes in an MPTP Induced Parkinson's Disease Mouse Model. (Q55177664) (← links)
• Perinatal Hypoxic-Ischemic Encephalopathy and Neuroprotective Peptide Therapies: A Case for Cationic Arginine-Rich Peptides (CARPs) (Q57929840) (← links)
• The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication (Q61800834) (← links)
• Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo (Q64249321) (← links)
• Rapid, quantitative therapeutic screening for Alzheimer's enzymes enabled by optimal signal transduction with transistors (Q90225298) (← links)
• Identification of Quinazolinone Analogs Targeting CDK5 Kinase Activity and Glioblastoma Cell Proliferation (Q99712127) (← links)