Pages that link to "Q28509265"
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The following pages link to TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo (Q28509265):
Displaying 50 items.
- Tyrosyl-DNA phosphodiesterase 1 (Q21992244) (← links)
- A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage (Q24319904) (← links)
- Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation (Q24337706) (← links)
- Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK (Q24644674) (← links)
- PP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues (Q26823704) (← links)
- R-loops in proliferating cells but not in the brain: implications for AOA2 and other autosomal recessive ataxias (Q27318630) (← links)
- Analysis of the Active-Site Mechanism of Tyrosyl-DNA Phosphodiesterase I: A Member of the Phospholipase D Superfamily (Q27676072) (← links)
- Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks (Q27967652) (← links)
- Processing of damaged DNA ends for double-strand break repair in mammalian cells (Q28000148) (← links)
- TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function (Q28118952) (← links)
- The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1 (Q28513565) (← links)
- DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition (Q29400901) (← links)
- Single-strand break repair and genetic disease (Q29615347) (← links)
- Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage. (Q33615689) (← links)
- Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria (Q33735624) (← links)
- In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation (Q33747764) (← links)
- The DNA binding and 3'-end preferential activity of human tyrosyl-DNA phosphodiesterase (Q33783186) (← links)
- Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes (Q33816985) (← links)
- Mutant huntingtin impairs Ku70-mediated DNA repair (Q33840010) (← links)
- SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability (Q33847786) (← links)
- Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2). (Q33875792) (← links)
- Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform (Q34017010) (← links)
- Biochemical assays for the discovery of TDP1 inhibitors (Q34021070) (← links)
- Thiopurine methyltransferase predicts the extent of cytotoxicty and DNA damage in astroglial cells after thioguanine exposure. (Q34117269) (← links)
- DNA repair deficiency in neurodegeneration. (Q34183328) (← links)
- Patching and Single-Strand Ligation in Nonhomologous DNA End Joining Despite Persistence of a Closely Opposed 3′-Phosphoglycolate-Terminated Strand Break (Q34207370) (← links)
- Neuroprotection and repair of 3'-blocking DNA ends by glaikit (gkt) encoding Drosophila tyrosyl-DNA phosphodiesterase 1 (TDP1). (Q34480920) (← links)
- Neurological disorders associated with DNA strand-break processing enzymes (Q34535722) (← links)
- DNA repair mechanisms in dividing and non-dividing cells (Q34727858) (← links)
- Poly(ADP-ribose) polymerase and XPF–ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells (Q34946954) (← links)
- Development of an oligonucleotide-based fluorescence assay for the identification of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors. (Q35122653) (← links)
- Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) inhibitors (Q35167579) (← links)
- The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis (Q35551473) (← links)
- Disconnecting XRCC1 and DNA ligase III (Q35878514) (← links)
- Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells (Q35921514) (← links)
- Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia (Q36268156) (← links)
- TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1. (Q36280725) (← links)
- DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. (Q36588889) (← links)
- Topoisomerase IIβ deficiency enhances camptothecin-induced apoptosis (Q36666233) (← links)
- The involvement of DNA-damage and -repair defects in neurological dysfunction (Q36718848) (← links)
- DNA damage and repair: relevance to mechanisms of neurodegeneration (Q36775988) (← links)
- Brain capacity for repair of oxidatively damaged DNA and preservation of neuronal function (Q37122200) (← links)
- TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs (Q37148469) (← links)
- DNA strand breaks, neurodegeneration and aging in the brain (Q37154126) (← links)
- Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining (Q37365625) (← links)
- DNA repair deficiency and neurological disease (Q37368873) (← links)
- 4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesulfonate) (NSC 88915) and related novel steroid derivatives as tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors (Q37445367) (← links)
- Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel (Q37572609) (← links)
- PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage (Q37701295) (← links)
- Spinocerebellar Ataxia with Axonal Neuropathy (Q37778035) (← links)