Pages that link to "Q27642877"
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The following pages link to Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system (Q27642877):
Displaying 20 items.
- Insights into Phosphate Cooperativity and Influence of Substrate Modifications on Binding and Catalysis of Hexameric Purine Nucleoside Phosphorylases (Q27672664) (← links)
- New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A (Q27678965) (← links)
- Progress and problems with the use of suicide genes for targeted cancer therapy (Q28262370) (← links)
- Coupling Protein Side-Chain and Backbone Flexibility Improves the Re-design of Protein-Ligand Specificity (Q28914714) (← links)
- Toward a high-throughput screening platform for directed evolution of enzymes that activate genotoxic prodrugs. (Q35201410) (← links)
- Enhancement of intratumoral cyclophosphamide pharmacokinetics and antitumor activity in a P450 2B11-based cancer gene therapy model (Q37037051) (← links)
- Development of gene therapy in association with clinically used cytotoxic deoxynucleoside analogues. (Q37431500) (← links)
- PRE-CLINICAL AND CLINICAL VALIDATION OF AN ANTI-CANCER MODALITY THAT ABLATES REFRACTORY, LOW GROWTH FRACTION TUMORS. (Q37563779) (← links)
- Enzymes to die for: exploiting nucleotide metabolizing enzymes for cancer gene therapy (Q37989984) (← links)
- Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase (Q39577776) (← links)
- Homooligomerization is needed for stability: a molecular modelling and solution study of Escherichia coli purine nucleoside phosphorylase (Q40188047) (← links)
- Activators of viral gene expression in polarized epithelial monolayers identified by rapid-throughput drug screening. (Q40347903) (← links)
- Design and evaluation of 5'-modified nucleoside analogs as prodrugs for an E. coli purine nucleoside phosphorylase mutant (Q40358231) (← links)
- Unique substrate specificity of purine nucleoside phosphorylases from Thermus thermophilus (Q43018050) (← links)
- Use of E. coli Purine Nucleoside Phosphorylase in the Treatment of Solid Tumors (Q47422296) (← links)
- Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis (Q58603689) (← links)
- A Metabolism Toolbox for CAR T Therapy (Q64078967) (← links)
- Putative vaccine candidates and drug targets identified by reverse vaccinology and subtractive genomics approaches to control Haemophilus ducreyi, the causative agent of chancroid. (Q64964854) (← links)
- Crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with acyclovir (Q89402237) (← links)
- Intratumoral generation of 2-fluoroadenine to treat solid malignancies of the head and neck (Q91000647) (← links)