Pages that link to "Q48645885"
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The following pages link to The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A. (Q48645885):
Displaying 50 items.
- Biology of PXR: role in drug-hormone interactions (Q26822721) (← links)
- Metabolomics: A Tool Ahead for Understanding Molecular Mechanisms of Drugs and Diseases (Q26827107) (← links)
- PXR variants: the impact on drug metabolism and therapeutic responses (Q28080023) (← links)
- Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator (Q33606444) (← links)
- Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice (Q33756030) (← links)
- Comparative study of the effects of antituberculosis drugs and antiretroviral drugs on cytochrome P450 3A4 and P-glycoprotein (Q33797986) (← links)
- Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation (Q34214649) (← links)
- Bisphenol A increases atherosclerosis in pregnane X receptor-humanized ApoE deficient mice (Q34297158) (← links)
- Pregnane X receptor and drug-induced liver injury. (Q34345049) (← links)
- Pregnane X Receptor and Constitutive Androstane Receptor at the Crossroads of Drug Metabolism and Energy Metabolism (Q34359458) (← links)
- The Chinese Herbal Medicine Sophora flavescens Activates Pregnane X Receptor (Q34359510) (← links)
- Pregnane X receptor-mediated induction of Cyp3a by black cohosh (Q34482267) (← links)
- Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models (Q34513706) (← links)
- Pregnane X receptor- and CYP3A4-humanized mouse models and their applications (Q35005644) (← links)
- Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2, and CYP3 genes in developing zebrafish (Q35014430) (← links)
- Serine 350 of human pregnane X receptor is crucial for its heterodimerization with retinoid X receptor alpha and transactivation of target genes in vitro and in vivo (Q35920690) (← links)
- Small-molecule modulators of PXR and CAR. (Q35938150) (← links)
- Pregnane X Receptor-Humanized Mice Recapitulate Gender Differences in Ethanol Metabolism but Not Hepatotoxicity (Q35962050) (← links)
- Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver (Q36316485) (← links)
- Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance. (Q36498311) (← links)
- Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo (Q36511932) (← links)
- Cytochrome P450 regulation by α-tocopherol in Pxr-null and PXR-humanized mice (Q36573346) (← links)
- Role of CAR and PXR in xenobiotic sensing and metabolism (Q36672089) (← links)
- Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy (Q36745429) (← links)
- A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response. (Q36804898) (← links)
- Preclinical predictors of clinical safety: opportunities for improvement (Q36824536) (← links)
- The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes (Q36953154) (← links)
- PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics (Q36995453) (← links)
- Humanized mouse lines and their application for prediction of human drug metabolism and toxicological risk assessment (Q37002739) (← links)
- Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation (Q37151846) (← links)
- A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4 (Q37183874) (← links)
- Phosphorylation and protein-protein interactions in PXR-mediated CYP3A repression (Q37284901) (← links)
- Activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by herbal medicines (Q37378074) (← links)
- The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism (Q37400616) (← links)
- Role of pregnane X receptor in obesity and glucose homeostasis in male mice (Q37563409) (← links)
- Predicting the clinical relevance of drug interactions from pre-approval studies. (Q37610142) (← links)
- Combining Chimeric Mice with Humanized Liver, Mass Spectrometry, and Physiologically-Based Pharmacokinetic Modeling in Toxicology. (Q37624853) (← links)
- Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells. (Q37746377) (← links)
- Hepatic drug-metabolizing enzyme induction and implications for preclinical and clinical risk assessment (Q37771144) (← links)
- Xenobiotic metabolomics: major impact on the metabolome (Q37912165) (← links)
- Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response (Q38039759) (← links)
- Xenobiotic receptor humanized mice and their utility (Q38061645) (← links)
- Nuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond (Q38074718) (← links)
- Nuclear receptors in herb-drug interactions. (Q38074992) (← links)
- PXR cross-talks with internal and external signals in physiological and pathophysiological responses (Q38108791) (← links)
- Novel pre-clinical methodologies for pharmacokinetic drug-drug interaction studies: spotlight on "humanized" animal models. (Q38255685) (← links)
- Comparative genomics of xenobiotic metabolism: a porcine-human PXR gene comparison. (Q38302710) (← links)
- The novel antibacterial compound walrycin A induces human PXR transcriptional activity (Q38327914) (← links)
- SPA70 is a potent antagonist of human pregnane X receptor. (Q42367857) (← links)
- Cyclic AMP-dependent protein kinase signaling modulates pregnane x receptor activity in a species-specific manner (Q43167106) (← links)