Pages that link to "Q44588830"
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The following pages link to Inhibition of PI-3 kinase sensitizes human leukemic cells to histone deacetylase inhibitor-mediated apoptosis through p44/42 MAP kinase inactivation and abrogation of p21(CIP1/WAF1) induction rather than AKT inhibition (Q44588830):
Displaying 41 items.
- Synergistic antileukemic interactions between 2-medroxyestradiol (2-ME) and histone deacetylase inhibitors involve Akt down-regulation and oxidative stress (Q23918915) (← links)
- Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells (Q24644201) (← links)
- Epigenetics in Brain Tumors: HDACs Take Center Stage (Q28080964) (← links)
- Preclinical evaluation of dual PI3K-mTOR inhibitors and histone deacetylase inhibitors in head and neck squamous cell carcinoma (Q28395338) (← links)
- Anticancer activities of histone deacetylase inhibitors (Q29616624) (← links)
- Protective effects of butyrate-based compounds on a mouse model for spinal muscular atrophy. (Q30743508) (← links)
- Vorinostat interferes with the signaling transduction pathway of T-cell receptor and synergizes with phosphoinositide-3 kinase inhibitors in cutaneous T-cell lymphoma. (Q33800456) (← links)
- Rational combination of dual PI3K/mTOR blockade and Bcl-2/-xL inhibition in AML. (Q33840360) (← links)
- A phase I study of vorinostat in combination with idarubicin in relapsed or refractory leukaemia (Q34014818) (← links)
- PI3K/mTOR inhibition markedly potentiates HDAC inhibitor activity in NHL cells through BIM- and MCL-1-dependent mechanisms in vitro and in vivo (Q34199935) (← links)
- Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress (Q34359570) (← links)
- Histone deacetylase inhibitors in clinical development (Q35609717) (← links)
- Rational Combinations of Targeted Agents in AML (Q35750491) (← links)
- The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress (Q35950143) (← links)
- Emerging drugs for the treatment of myelodysplastic syndrome (Q36219655) (← links)
- Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01 (Q36614208) (← links)
- Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism. (Q36625664) (← links)
- Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations (Q36742629) (← links)
- A phase I trial of vorinostat and alvocidib in patients with relapsed, refractory, or poor prognosis acute leukemia, or refractory anemia with excess blasts-2. (Q36745599) (← links)
- The phosphatidylinositol 3-kinases (PI3K) inhibitor GS-1101 synergistically potentiates histone deacetylase inhibitor-induced proliferation inhibition and apoptosis through the inactivation of PI3K and extracellular signal-regulated kinase pathways. (Q37200384) (← links)
- The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathways (Q37420518) (← links)
- Enhanced FGFR signalling predisposes pancreatic cancer to the effect of a potent FGFR inhibitor in preclinical models (Q37507462) (← links)
- Class I HDACs Affect DNA Replication, Repair, and Chromatin Structure: Implications for Cancer Therapy (Q38204487) (← links)
- BIM upregulation and ROS-dependent necroptosis mediate the antitumor effects of the HDACi Givinostat and Sorafenib in Hodgkin lymphoma cell line xenografts. (Q39021652) (← links)
- Combination of a novel HDAC inhibitor OBP-801/YM753 and a PI3K inhibitor LY294002 synergistically induces apoptosis in human endometrial carcinoma cells due to increase of Bim with accumulation of ROS. (Q39195722) (← links)
- Aminopeptidase-N/CD13 is a potential proapoptotic target in human myeloid tumor cells (Q39544012) (← links)
- Butyrate regulates the expression of inflammatory and chemotactic cytokines in human acute leukemic cells during apoptosis (Q39715810) (← links)
- Role of dephosphorylation of FOXO1 on apoptosis induced by wortmannin for non-Hodgkin's lymphoma cells (Q39799071) (← links)
- Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation (Q40336251) (← links)
- Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation (Q40383692) (← links)
- 2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process. (Q40455972) (← links)
- Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mRNA stabilization (Q40600789) (← links)
- Sp1-mediated TRAIL induction in chemosensitization (Q43193517) (← links)
- Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis (Q46500208) (← links)
- Nerve growth factor activates aorta endothelial cells causing PI3K/Akt- and ERK-dependent migration (Q46517102) (← links)
- Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53. (Q47136872) (← links)
- Metabolomic Profiling Reveals Cellular Reprogramming of B-Cell Lymphoma by a Lysine Deacetylase Inhibitor through the Choline Pathway (Q49359645) (← links)
- Epigenetic Targeting of Autophagy via HDAC Inhibition in Tumor Cells: Role of p53 (Q60907794) (← links)
- Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia (Q92022530) (← links)
- p53 at the Crossroads between Different Types of HDAC Inhibitor-Mediated Cancer Cell Death (Q92083193) (← links)
- Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy (Q92445781) (← links)