Pages that link to "Q42509261"
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The following pages link to The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway (Q42509261):
Displaying 50 items.
- Correlation between the biochemical pathways altered by mutated Parkinson-related genes and chronic exposure to manganese (Q23914777) (← links)
- Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation (Q24297033) (← links)
- Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy (Q24307769) (← links)
- Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson's Disease (Q26746897) (← links)
- Emerging preclinical pharmacological targets for Parkinson's disease (Q26764724) (← links)
- The associations between Parkinson's disease and cancer: the plot thickens (Q26778641) (← links)
- Mitochondria: A Therapeutic Target for Parkinson's Disease? (Q26784216) (← links)
- The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease (Q26853537) (← links)
- Autophagy and neurodegeneration (Q26991692) (← links)
- Heterogeneity of leucine-rich repeat kinase 2 mutations: genetics, mechanisms and therapeutic implications (Q27013695) (← links)
- The role of the LRRK2 gene in Parkinsonism (Q27023749) (← links)
- Leucine-rich repeat kinase 2 (LRRK2)-deficient rats exhibit renal tubule injury and perturbations in metabolic and immunological homeostasis (Q27315276) (← links)
- Dysregulation of autophagy and mitochondrial function in Parkinson's disease (Q28071890) (← links)
- Genetics in Parkinson disease: Mendelian versus non-Mendelian inheritance (Q28077356) (← links)
- LRRK2 at the interface of autophagosomes, endosomes and lysosomes (Q28078248) (← links)
- Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation (Q28115231) (← links)
- Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression (Q28115890) (← links)
- Inhibition of LRRK2 kinase activity stimulates macroautophagy (Q28118311) (← links)
- mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1 (Q28822211) (← links)
- ERKed by LRRK2: a cell biological perspective on hereditary and sporadic Parkinson's disease (Q33593798) (← links)
- Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy (Q33920691) (← links)
- Autophagy plays a critical role in ChLym-1-induced cytotoxicity of non-hodgkin's lymphoma cells (Q34981512) (← links)
- A mycobacterial phosphoribosyltransferase promotes bacillary survival by inhibiting oxidative stress and autophagy pathways in macrophages and zebrafish (Q35590766) (← links)
- ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression (Q36923141) (← links)
- LRRK2: cause, risk, and mechanism (Q37635000) (← links)
- Targeting leucine-rich repeat kinase 2 in Parkinson's disease (Q38160939) (← links)
- LRRK2, a puzzling protein: insights into Parkinson's disease pathogenesis (Q38218398) (← links)
- Defective autophagy in Parkinson's disease: lessons from genetics (Q38225786) (← links)
- Cellular processes associated with LRRK2 function and dysfunction (Q38433725) (← links)
- Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis (Q38533700) (← links)
- Targeting the Autophagy/Lysosomal Degradation Pathway in Parkinson's Disease. (Q38620227) (← links)
- LRRK2 at the Crossroad Between Autophagy and Microtubule Trafficking: Insights into Parkinson's Disease. (Q38689010) (← links)
- LRRK2 and Autophagy (Q38869514) (← links)
- Autophagy-from molecular mechanisms to clinical relevance. (Q39037205) (← links)
- Prelysosomal Compartments in the Unconventional Secretion of Amyloidogenic Seeds (Q39104462) (← links)
- Sec16 in conventional and unconventional exocytosis: Working at the interface of membrane traffic and secretory autophagy? (Q39119334) (← links)
- The LRRK2-macroautophagy axis and its relevance to Parkinson's disease (Q39137355) (← links)
- Association of the LRRK2 genetic polymorphisms with leprosy in Han Chinese from Southwest China (Q41592813) (← links)
- A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease (Q41776543) (← links)
- An early axonopathy in a hLRRK2(R1441G) transgenic model of Parkinson disease. (Q41916939) (← links)
- Parkinson's disease: leucine-rich repeat kinase 2 and autophagy, intimate enemies. (Q42324120) (← links)
- Autophagy impairment in Parkinson's disease. (Q47301116) (← links)
- Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants (Q47643867) (← links)
- Drosophila hep pathway mediates Lrrk2-induced neurodegeneration. (Q50135395) (← links)
- Dermal fibroblasts from patients with Parkinson's disease have normal GCase activity and autophagy compared to patients with PD and GBA mutations (Q50419934) (← links)
- Interaction of LRRK2 and α-Synuclein in Parkinson's Disease (Q51082143) (← links)
- Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression. (Q53387936) (← links)
- Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. (Q54972398) (← links)
- Exhaustion of mitochondrial and autophagic reserve may contribute to the development of LRRK2 G2019S -Parkinson's disease. (Q54976661) (← links)
- In Vitro Modeling of Leucine-Rich Repeat Kinase 2 (LRRK2) G2019S-Mediated Parkinson's Disease Pathology. (Q54984575) (← links)