CAMP responsive element binding protein 1 (Q21116771)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16220

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Coactivator CBP, pKID, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

DNA-binding transcription factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

DNA-binding transcription activator activity, RNA polymerase II-specific

Norwegian University of Science and Technology, Systems Biology team

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

cAMP response element binding

1 reference

8 April 2019

cJun modulates Ggamma-globin gene expression via an upstream cAMP response element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

transcription coregulator activity

1 reference

8 April 2019

Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

RNA polymerase II cis-regulatory region sequence-specific DNA binding

enzyme binding

1 reference

8 April 2019

A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

protein binding

16 references

8 April 2019

Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

Lyl1 interacts with CREB1 and alters expression of CREB1 target genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

A human MAP kinase interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

cAMP-independent activation of the adenovirus type 12 E2 promoter correlates with the recruitment of CREB-1/ATF-1, E1A(12S), and CBP to the E2-CRE

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per‐Arnt‐Sim domain kinase PASKIN

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

PML/RARalpha targets promoter regions containing PU.1 consensus and RARE half sites in acute promyelocytic leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

TSSK5, a novel member of the testis-specific serine/threonine kinase family, phosphorylates CREB at Ser-133, and stimulates the CRE/CREB responsive pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

double-stranded DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

DNA binding

sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

identical protein binding

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

3 references

5 June 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

NAS

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

Norwegian University of Science and Technology, Systems Biology team

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

transcription factor binding

ISA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

Hsp70 protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

histone acetyltransferase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

arrestin family protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

5 references

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

NAS

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

Norwegian University of Science and Technology, Systems Biology team

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

cJun modulates Ggamma-globin gene expression via an upstream cAMP response element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

cJun modulates Ggamma-globin gene expression via an upstream cAMP response element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

Norwegian University of Science and Technology, Systems Biology team

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

cell component

mitochondrion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

ATF4-CREB1 transcription factor complex

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

chromatin

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

transcription regulator complex

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

axon

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

mitochondrial matrix

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

cellular response to nerve growth factor stimulus

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

positive regulation of long-term synaptic potentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

rhythmic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

1 reference

8 April 2019

cellular response to insulin-like growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

response to organic substance

1 reference

8 April 2019

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

mammary gland development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

protein phosphorylation

1 reference

8 April 2019

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

type I pneumocyte differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

positive regulation of multicellular organism growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

response to L-glutamate

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

lung saccule development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

lung epithelium development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

transforming growth factor beta receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

cellular response to transforming growth factor beta stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

negative regulation of transcription by competitive promoter binding

1 reference

8 April 2019

cJun modulates Ggamma-globin gene expression via an upstream cAMP response element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

response to nicotine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

positive regulation of osteoclast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

memory

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

negative regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

1 reference

5 June 2018

lactation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

positive regulation of transforming growth factor beta3 production

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

viral process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

1 reference

8 April 2019

negative regulation of neuron death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

1 reference

8 April 2019

cellular response to hepatocyte growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

cellular response to platelet-derived growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

regulation of circadian rhythm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

secretory granule organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

regulation of glial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

visual learning

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

regulation of cell size

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

pituitary gland development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

positive regulation of RNA polymerase II transcription preinitiation complex assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

response to hypoxia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

axonogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

regulation of fibroblast proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

cellular response to growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

ageing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

chemotaxis to arachidonic acid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

response to activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

cellular response to zinc ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

cellular response to fatty acid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

positive regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

positive regulation of hormone secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

signal transduction

1 reference

8 April 2019

Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

positive regulation of transcription by RNA polymerase II

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

5 June 2018

The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

5 June 2018

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

5 June 2018

cJun modulates Ggamma-globin gene expression via an upstream cAMP response element

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16220&geneProductId=UniProtKB:P16220

positive regulation of cardiac muscle tissue development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

cellular response to leukemia inhibitory factor

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

positive regulation of transcription by RNA polymerase II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

5 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

8 April 2019

cJun modulates Ggamma-globin gene expression via an upstream cAMP response element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16220

Basic-leucine zipper domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16220

Coactivator CBP, pKID

1 reference

InterPro Release 71.0