C-C motif chemokine ligand 1 (Q21172202)

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mammalian protein found in Homo sapiens

inflammatory cytokine I-309
Small-inducible cytokine A1
C-C motif chemokine 1
T lymphocyte-secreted protein I-309
small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
chemokine (C-C motif) ligand 1
CCL1

Language	Label	Description	Also known as
English	C-C motif chemokine ligand 1	mammalian protein found in Homo sapiens	inflammatory cytokine I-309 Small-inducible cytokine A1 C-C motif chemokine 1 T lymphocyte-secreted protein I-309 small inducible cytokine A1 (I-309, homologous to mouse Tca-3) chemokine (C-C motif) ligand 1 CCL1

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

cytokine activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

CCR chemokine receptor binding

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

chemokine activity

determination method or standard

3 references

16 July 2018

The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22362&geneProductId=UniProtKB:P22362

determination method or standard

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22362&geneProductId=UniProtKB:P22362

determination method or standard

16 July 2018

The human cytokine I-309 is a monocyte chemoattractant

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22362&geneProductId=UniProtKB:P22362

determination method or standard

chemokine activity

determination method or standard

4 references

8 April 2019

The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

8 April 2019

The human cytokine I-309 is a monocyte chemoattractant

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

extracellular region

determination method or standard

extracellular space

determination method or standard

3 references

16 July 2018

Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22362&geneProductId=UniProtKB:P22362

determination method or standard

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22362&geneProductId=UniProtKB:P22362

determination method or standard

16 July 2018

The human cytokine I-309 is a monocyte chemoattractant

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22362&geneProductId=UniProtKB:P22362

determination method or standard

extracellular space

determination method or standard

4 references

8 April 2019

Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

8 April 2019

The human cytokine I-309 is a monocyte chemoattractant

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

biological process

chemokine-mediated signaling pathway

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

cellular response to tumor necrosis factor

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

cellular calcium ion homeostasis

determination method or standard

1 reference

8 April 2019

The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

neutrophil chemotaxis

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

positive regulation of GTPase activity

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

cellular response to interleukin-1

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

immune response

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

positive regulation of ERK1 and ERK2 cascade

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

cellular response to interferon-gamma

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

lymphocyte chemotaxis

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

inflammatory response

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

determination method or standard

1 reference

8 April 2019

The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

signal transduction

determination method or standard

1 reference

8 April 2019

The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

positive regulation of cytosolic calcium ion concentration

determination method or standard

1 reference

8 April 2019

The human cytokine I-309 is a monocyte chemoattractant

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

antimicrobial humoral immune response mediated by antimicrobial peptide

determination method or standard

1 reference

31 January 2018

Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22362&geneProductId=UniProtKB:P22362

determination method or standard

positive regulation of monocyte chemotaxis

determination method or standard

1 reference

8 April 2019

The human cytokine I-309 is a monocyte chemoattractant

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

regulation of signaling receptor activity

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

positive regulation of inflammatory response

determination method or standard

1 reference

8 April 2019

MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and CCL1 in patients with Vogt-Koyanagi-Harada disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

monocyte chemotaxis

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

eosinophil chemotaxis

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22362

determination method or standard

Identifiers

MeSH descriptor ID

subject named as

Chemokine CCL1

0 references

D12.644.276.374.200.110.050

0 references

D12.776.467.374.200.110.050

0 references

D23.125.300.110.050

0 references

D23.469.200.110.050

0 references

D23.529.374.200.110.050

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000225842

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000225842

1 reference

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

0 references

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(9 entries)

bswiki CCL1
dewiki CCL1
enwiki CCL1
hywiki CCL1
shwiki CCL1
srwiki CCL1
ttwiki CCL1
ukwiki CCL1
zhwiki CCL1

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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