Nemo like kinase (Q6594108)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UBE8

Protein kinase domain, protein family

1 reference

Mitogen-activated protein (MAP) kinase, conserved site, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

1 reference

8 April 2019

transcription factor binding

2 references

8 April 2019

NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

Stabilization of ATF5 by TAK1-Nemo-like kinase critically regulates the interleukin-1β-stimulated C/EBP signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

1 reference

8 April 2019

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

1 reference

8 April 2019

protein binding

9 references

8 April 2019

The protein interaction landscape of the human CMGC kinase group

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

ubiquitin protein ligase binding

1 reference

8 April 2019

NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

protein serine/threonine kinase activity

ATP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

protein kinase activity

Characterization of the Fugu rubripes NLK and FN5 genes flanking the NF1 (Neurofibromatosis type 1) gene in the 5' direction and mapping of the human counterparts

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

MAP kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBE8&geneProductId=UniProtKB:Q9UBE8

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBE8&geneProductId=UniProtKB:Q9UBE8

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBE8&geneProductId=UniProtKB:Q9UBE8

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBE8&geneProductId=UniProtKB:Q9UBE8

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBE8&geneProductId=UniProtKB:Q9UBE8

24 April 2018

MAP kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

cell component

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

1 reference

8 April 2019

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

1 reference

8 April 2019

nucleus

Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

biological process

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

1 reference

8 April 2019

protein stabilization

IDA

1 reference

8 April 2019

Stabilization of ATF5 by TAK1-Nemo-like kinase critically regulates the interleukin-1β-stimulated C/EBP signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

IDA

Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

1 reference

8 April 2019

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UBE8&geneProductId=UniProtKB:Q9UBE8

1 reference

24 April 2018

MAPK cascade

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

protein autophosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

transforming growth factor beta receptor signaling pathway

IMP

1 reference

8 April 2019

Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

Wnt signaling pathway, calcium modulating pathway

IMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

1 reference

8 April 2019

protein phosphorylation

regulation of gene expression

ISS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

intracellular signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBE8