vincristine (Q408977)

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chemical compound

22-oxovincaleukoblastine
kyocristine
leurocristine sulfate
NSC-67574
Oncovin®
leurocristine
Leurocristine
Vincristin
Vincristinum
Vincristine
22-Oxovincaleukoblastine
Vincristina
22-Oxovincaleukoblastin

Language	Label	Description	Also known as
English	vincristine	chemical compound	22-oxovincaleukoblastine kyocristine leurocristine sulfate NSC-67574 Oncovin® leurocristine Leurocristine Vincristin Vincristinum Vincristine 22-Oxovincaleukoblastine Vincristina 22-Oxovincaleukoblastin

Statements

type of chemical entity

0 references

Vinca alkaloids

1 reference

27 February 2018

aspidospermine / aspidofractine / kopsane alkaloid

0 references

0 references

chemical structure

Vincristine.svg
1,712 × 1,292; 9 KB

0 references

image of molecular model or crystal lattice model

Vincristine3DanBS.gif
256 × 256; 577 KB

ball-and-stick model

0 references

824.399644 dalton

1 reference

language of work or name

vincristine (English)

3 October 2016

stereoisomer of

1 reference

based on heuristic

inferred from InChI

chemical formula

C₄₆H₅₆N₄O₁₀

1 reference

language of work or name

vincristine (English)

3 October 2016

canonical SMILES

CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O

1 reference

language of work or name

vincristine (English)

3 October 2016

isomeric SMILES

CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O

1 reference

language of work or name

vincristine (English)

3 October 2016

active ingredient in

1 reference

15 February 2018

Catharanthus roseus

8 references

Alkaloid Production in Root and Shoot Cultures of Catharanthus roseus

Analysis of Antitumor Antibiotics by High Pressure Liquid Chromatography (HPLC)

Determination of Vincristine and Vinblastine in Catharanthus roseus Plants by High Performance Liquid Chromatography/ Electrospray Ionization Mass Spectrometry

Extraction and in situ densitometric determination of alkaloids from Catharanthus roseus by means of overpressured layer chromatography on amino-bonded silica layers I. Optimization and validation of the separation system

Quantification of vincristine and vinblastine in Catharanthus roseus plants by capillary zone electrophoresis

SIMULTANEOUS DETERMINATION OF CATHARANTHUS ALKALOIDS USING REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

Supercritical fluid extraction and liquid chromatography-electrospray mass analysis of vinblastine from Catharanthus roseus

Symmetry C18 column: a better choice for the analysis of indole alkaloids of Catharanthus roseus

Taxus cuspidata

4 references

Effects of taxoids from Taxus cuspidata on microtubule depolymerization and vincristine accumulation in MDR cells

Biological activity and chemistry of taxoids from the Japanese yew, Taxus cuspidata.

Modulation of multidrug resistance by taxuspine C and other taxoids from Japanese yew

Taxoids and abietanes from callus cultures of Taxus cuspidata

Ophioparma ventosa

1 reference

Minor Pyranonaphthoquinones from the Apothecia of the Lichen Ophioparma ventosa

Nocardiopsis lucentensis

1 reference

Nocarbenzoxazoles A-G, Benzoxazoles Produced by Halophilic Nocardiopsis lucentensis DSM 44048.

medical condition treated

Hodgkin's lymphoma, mixed cellularity

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

rhabdomyosarcoma

1 reference

language of work or name

13 December 2016

1 reference

language of work or name

13 December 2016

chronic lymphocytic leukemia

1 reference

Drug Indications Extracted from FAERS

2 October 2018

precursor T-cell acute lymphoblastic leukemia

1 reference

Drug Indications Extracted from FAERS

2 October 2018

non-Hodgkin lymphoma

1 reference

Drug Indications Extracted from FAERS

2 October 2018

1 reference

Drug Indications Extracted from FAERS

2 October 2018

B-cell lymphoma

1 reference

Drug Indications Extracted from FAERS

2 October 2018

diffuse large B-cell lymphoma

1 reference

Drug Indications Extracted from FAERS

2 October 2018

lymphoblastic leukemia

8 August 2012

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/5J49Q6B70F

http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202497s000lbl.pdf

0 references

significant drug interaction

bone marrow failure

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

peripheral neuropathy

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

peripheral neuropathy

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

paralytic ileus

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

toxic encephalopathy

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

Tubulin beta class I

subject has role

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

pregnancy category

Australian pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

subject has role

tubulin modulators

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

phytogenic antineoplastic agents

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

essential medicine

0 references

0 references

mitotic inhibitor

0 references

vinCRIStine

has characteristic

Tall Man lettering

Food and Drug Administration

subject named as

Vincristine

1 reference

https://www.fda.gov/drugs/medication-errors-related-cder-regulated-drug-products/fda-name-differentiation-project

2 September 2022

NCI Thesaurus ID

C933

1 reference

Global Substance Registration System

15 February 2018

0 references

0 references

1 reference

imported from Wikimedia project

English Wikipedia

Wikimedia import URL

https://en.wikipedia.org/w/index.php?title=Vincristine&oldid=950717314

Commons category

Vincristine

0 references

Identifiers

InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1

1 reference

language of work or name

vincristine (English)

3 October 2016

OGWKCGZFUXNPDA-XQKSVPLYSA-N

2 references

language of work or name

vincristine (English)

3 October 2016

ChEBI release 2020-09-01

CAS Registry Number

2 references

language of work or name

Vincristine (English)

3 October 2016

Global Substance Registration System

15 February 2018

1 reference

language of work or name

vincristine (English)

3 October 2016

2 references

language of work or name

vincristine (English)

3 October 2016

matched by identifier from

OGWKCGZFUXNPDA-XQKSVPLYSA-N

Reaxys registry number

4779289

1 reference

language of work or name

vincristine (English)

3 October 2016

mapping relation type

2 references

language of work or name

vincristine (English)

3 October 2016

matched by identifier from

International Chemical Identifier

InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1

1 reference

language of work or name

VINCRISTINE (English)

3 October 2016

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

OGWKCGZFUXNPDA-XQKSVPLYSA-N

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

OGWKCGZFUXNPDA-XQKSVPLYSA-N

UniChem compound ID

1 reference

MassBank accession ID

MSBNK-RIKEN_ReSpect-PM000606

1 reference

OGWKCGZFUXNPDA-XQKSVPLYSA-N

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

based on heuristic

splash10-0a4i-0000000490-68650b7a4a681c60b75d

0 references

1 reference

Hazardous Substances Data Bank

publication date

28 October 2019

VINCRISTINE (English)

10 May 2021

DSSTox substance ID

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

matched by identifier from

OGWKCGZFUXNPDA-XQKSVPLYSA-N

DSSTOX compound identifier

0 references

1 reference

Global Substance Registration System

15 February 2018

ECHA Substance Infocard ID

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Vincristine (English)

CAS no.: 57-22-7 (English)

1 reference

language of work or name

Vincristine (English)

publication date

17 November 2015

Guide to Pharmacology Ligand ID

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

vincristine (English)

3 October 2016

MeSH descriptor ID

subject named as

Vincristine

1 reference

Medical Subject Headings

MeSH descriptor ID

14 March 2018

D03.132.436.681.827.817

0 references

D03.633.100.473.402.681.827.817

0 references

D03.633.100.496.500.500.681.827.817

0 references

1 reference

Global Substance Registration System

15 February 2018

0 references

Human Metabolome Database ID

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

OGWKCGZFUXNPDA-XQKSVPLYSA-N

1 reference

language of work or name

vincristine (English)

3 October 2016

2 references

language of work or name

Vincristine (English)

3 October 2016

Global Substance Registration System

15 February 2018

MedlinePlus drug identifier

0 references

PatientsLikeMe treatment ID

0 references

1 reference

language of work or name

VINCRISTINE (English)

19 January 2016

Probes And Drugs ID

0 references

1 reference

language of work or name

vincristine (English)

3 October 2016

1 reference

6 April 2020

electronic Essential Medicines List medicine ID

1 reference

https://list.essentialmeds.org/medicines/108

eEML - Electronic Essential Medicines List (English)

23 October 2021

0 references

Encyclopædia Britannica Online ID

science/vincristine

subject named as

vincristine

0 references

1 reference

Freebase Data Dumps

publication date

28 October 2013

Gran Enciclopèdia Catalana ID

0 references

Gran Enciclopèdia Catalana ID (former scheme)

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

Store medisinske leksikon ID

mapping relation type

subject named as

vinkristin

1 reference

Great Norwegian Encyclopedia

5 June 2020

WikiProjectMed ID

0 references

WordNet 3.1 Synset ID

04543121-n

1 reference

Sitelinks

Wikipedia(34 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:Vincristine

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