Pages that link to "Q28274709"

The following pages link to ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background (Q28274709):

Displaying 50 items.

• Mutation analysis of the ATR gene in breast and ovarian cancer families (Q24810690) ‎ (← links)
• Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy (Q26745686) ‎ (← links)
• Cell-cycle checkpoints and cancer (Q28293996) ‎ (← links)
• DNA damage response genes and the development of cancer metastasis (Q28388312) ‎ (← links)
• ATR: an essential regulator of genome integrity (Q29547883) ‎ (← links)
• BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer (Q33252066) ‎ (← links)
• Replication stress and cancer (Q34473453) ‎ (← links)
• Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner (Q34676703) ‎ (← links)
• Histone modifiers in cancer: friends or foes? (Q35216079) ‎ (← links)
• Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase (Q35423647) ‎ (← links)
• Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR (Q35640593) ‎ (← links)
• Genome maintenance defects in cultured cells and mice following partial inactivation of the essential cell cycle checkpoint gene Hus1. (Q35676284) ‎ (← links)
• Germline mutation in ATR in autosomal- dominant oropharyngeal cancer syndrome. (Q35843205) ‎ (← links)
• DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP. (Q36124287) ‎ (← links)
• Tumor suppressor genetics (Q36252762) ‎ (← links)
• Structure and function of the components of the human DNA mismatch repair system (Q36521428) ‎ (← links)
• The ATR barrier to replication-born DNA damage. (Q36664049) ‎ (← links)
• ATR signalling: more than meeting at the fork (Q36918246) ‎ (← links)
• Haploinsufficiency of DNA Damage Response Genes and their Potential Influence in Human Genomic Disorders (Q37185705) ‎ (← links)
• Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice (Q37318166) ‎ (← links)
• Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells (Q37327269) ‎ (← links)
• Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice. (Q37328459) ‎ (← links)
• Facilitating replication under stress: an oncogenic function of MYC? (Q37492244) ‎ (← links)
• Is activation of the intra-S checkpoint in human fibroblasts an important factor in protection against UV-induced mutagenesis? (Q37530284) ‎ (← links)
• Ligand modulation of a dinuclear platinum compound leads to mechanistic differences in cell cycle progression and arrest (Q37599111) ‎ (← links)
• Importance of DNA damage checkpoints in the pathogenesis of human cancers (Q37776824) ‎ (← links)
• Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication (Q37936675) ‎ (← links)
• Haploinsufficiency in mouse models of DNA repair deficiency: modifiers of penetrance (Q37939634) ‎ (← links)
• Selective tumor killing based on specific DNA-damage response deficiencies (Q37976982) ‎ (← links)
• Charity begins at home: non-coding RNA functions in DNA repair (Q38079476) ‎ (← links)
• Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin (Q38937094) ‎ (← links)
• Decatenation checkpoint-defective melanomas are dependent on PI3K for survival (Q38988931) ‎ (← links)
• A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts (Q39035062) ‎ (← links)
• Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress (Q39285948) ‎ (← links)
• Autoregulatory mechanisms of phosphorylation of checkpoint kinase 1. (Q39303724) ‎ (← links)
• The DNA damage checkpoint pathway promotes extensive resection and nucleotide synthesis to facilitate homologous recombination repair and genome stability in fission yeast. (Q39769852) ‎ (← links)
• MLH1 deficiency enhances tumor cell sensitivity to ganciclovir (Q39870596) ‎ (← links)
• Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). (Q40026743) ‎ (← links)
• Cellular and clinical impact of haploinsufficiency for genes involved in ATR signaling (Q40120694) ‎ (← links)
• Disparate roles of ATR and ATM in immunoglobulin class switch recombination and somatic hypermutation (Q41892816) ‎ (← links)
• Haploinsufficiency of Tumor Suppressor Genes is Driven by the Cumulative Effect of microRNAs, microRNA Binding Site Polymorphisms and microRNA Polymorphisms: An In silico Approach (Q41932257) ‎ (← links)
• ATR and H2AX cooperate in maintaining genome stability under replication stress (Q43177489) ‎ (← links)
• Insulin-like Growth Factor 1 Receptor Signaling Is Required for Optimal ATR-CHK1 Kinase Signaling in Ultraviolet B (UVB)-irradiated Human Keratinocytes. (Q48012870) ‎ (← links)
• Mutations in the ataxia telangiectasia and rad3-related-checkpoint kinase 1 DNA damage response axis in colon cancers. (Q53526795) ‎ (← links)
• ATR inhibition preferentially targets homologous recombination-deficient tumor cells. (Q54326103) ‎ (← links)
• Thresholds of replication stress signaling in cancer development and treatment. (Q54538558) ‎ (← links)
• Mice hypomorphic for Atr have increased DNA damage and abnormal checkpoint response. (Q54740910) ‎ (← links)
• Life can be stressful without ATR (Q56930964) ‎ (← links)
• Mlh1 deficiency increases the risk of hematopoietic malignancy after simulated space radiation exposure (Q57058967) ‎ (← links)
• Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA (Q60044506) ‎ (← links)