Pages that link to "Q22337238"

The following pages link to A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging (Q22337238):

Displaying 50 items.

• Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome (Q21144903) ‎ (← links)
• Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling (Q24294774) ‎ (← links)
• CEP152 is a genome maintenance protein disrupted in Seckel syndrome (Q24312725) ‎ (← links)
• Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs (Q24610287) ‎ (← links)
• Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells (Q26740026) ‎ (← links)
• Current Evidence for Developmental, Structural, and Functional Brain Defects following Prenatal Radiation Exposure (Q26744282) ‎ (← links)
• ATR-mediated regulation of nuclear and cellular plasticity (Q26747245) ‎ (← links)
• Connecting the Dots: From DNA Damage and Repair to Aging (Q26750854) ‎ (← links)
• Modeling the study of DNA damage responses in mice (Q26826949) ‎ (← links)
• Diseases associated with defective responses to DNA damage (Q26997852) ‎ (← links)
• Understanding specific functions of PARP-2: new lessons for cancer therapy (Q28067486) ‎ (← links)
• The hallmarks of aging (Q28131641) ‎ (← links)
• Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging (Q28390091) ‎ (← links)
• Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome (Q28485037) ‎ (← links)
• A reduction of licensed origins reveals strain-specific replication dynamics in mice (Q28507067) ‎ (← links)
• CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination (Q28589697) ‎ (← links)
• Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress (Q30581882) ‎ (← links)
• Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML. (Q30823304) ‎ (← links)
• An essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stress (Q30824986) ‎ (← links)
• Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants (Q33549647) ‎ (← links)
• Intrauterine programming of ageing (Q33630731) ‎ (← links)
• The nuclear γ-H2AX apoptotic ring: implications for cancers and autoimmune diseases (Q33656349) ‎ (← links)
• ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase (Q33717036) ‎ (← links)
• Fos-dependent induction of Chk1 protects osteoblasts from replication stress (Q33953147) ‎ (← links)
• ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress (Q34001058) ‎ (← links)
• Applied Healthspan engineering (Q34157133) ‎ (← links)
• Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970 (Q34221860) ‎ (← links)
• Maternal aldehyde elimination during pregnancy preserves the fetal genome (Q34244123) ‎ (← links)
• Removing all obstacles: a critical role for p53 in promoting tissue renewal (Q34306322) ‎ (← links)
• The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain (Q34352305) ‎ (← links)
• DNA double-strand break signaling and human disorders (Q34360500) ‎ (← links)
• Causes and consequences of replication stress (Q34394094) ‎ (← links)
• Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling (Q34427583) ‎ (← links)
• SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair. (Q34528261) ‎ (← links)
• A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. (Q34531308) ‎ (← links)
• Increased Arf/p53 activity in stem cells, aging and cancer (Q34549629) ‎ (← links)
• Spartan deficiency causes genomic instability and progeroid phenotypes (Q34722436) ‎ (← links)
• Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1. (Q34727801) ‎ (← links)
• Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity (Q34845985) ‎ (← links)
• Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice (Q34997279) ‎ (← links)
• In vivo role of checkpoint kinase 2 in signaling telomere dysfunction (Q35093054) ‎ (← links)
• Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase (Q35171016) ‎ (← links)
• Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice (Q35293714) ‎ (← links)
• E2F1-dependent oncogenic addiction of melanoma cells to MDM2. (Q35353609) ‎ (← links)
• Aging--RNA in development and disease (Q35605882) ‎ (← links)
• DNA damage response and spindle assembly checkpoint function throughout the cell cycle to ensure genomic integrity (Q35610725) ‎ (← links)
• Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR (Q35640593) ‎ (← links)
• An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation (Q35825997) ‎ (← links)
• Germline mutation in ATR in autosomal- dominant oropharyngeal cancer syndrome. (Q35843205) ‎ (← links)
• 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response (Q35894239) ‎ (← links)