Ghrelin inhibits insulin secretion through the AMPK-UCP2 pathway in beta cells (Q39731784)

14 September 2017

title

Ghrelin inhibits insulin secretion through the AMPK-UCP2 pathway in beta cells (English)

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14 September 2017

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Hiroto Furuta

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14 September 2017

Ying Wang

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14 September 2017

Masahiro Nishi

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14 September 2017

Asako Doi

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14 September 2017

Takeshi Shono

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14 September 2017

Yasushi Furukawa

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14 September 2017

Takeshi Shimada

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14 September 2017

Hideyuki Sasaki

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14 September 2017

Kishio Nanjo

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14 September 2017

language of work or name

English

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publication date

3 March 2010

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14 September 2017

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14 September 2017

volume

584

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14 September 2017

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14 September 2017

page(s)

1503-1508

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Ghrelin is a growth-hormone-releasing acylated peptide from stomach

14 September 2017

cites work

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in beta-cells: implication in the glycemic control in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Ghrelin induces adiposity in rodents

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Ghrelin regulates adiposity in white adipose tissue and UCP1 mRNA expression in brown adipose tissue in mice

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Effects of ghrelin on the insulin and glycemic responses to glucose, arginine, or free fatty acids load in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Ghrelin regulates mitochondrial-lipid metabolism gene expression and tissue fat distribution in liver and skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Enhancing effect of taurine on glucose response in UCP2-overexpressing beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Insulin and contraction directly stimulate UCP2 and UCP3 mRNA expression in rat skeletal muscle in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Superoxide activates mitochondrial uncoupling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

Glucose deprivation regulates KATP channel trafficking via AMP-activated protein kinase in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.02.069

10.1016/J.FEBSLET.2010.02.069

21 January 2018

Identifiers

DOI

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14 September 2017

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