The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP. (Q39449044)

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English	The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP.	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

12 September 2017

The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP. (English)

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Europe PubMed Central

PMC publication ID

12 September 2017

author name string

A K Sil

1

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Europe PubMed Central

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12 September 2017

S Alam

2

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Europe PubMed Central

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12 September 2017

P Xin

3

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Europe PubMed Central

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12 September 2017

L Ma

4

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Europe PubMed Central

PMC publication ID

12 September 2017

M Morgan

5

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Europe PubMed Central

PMC publication ID

12 September 2017

C M Lebo

6

1 reference

Europe PubMed Central

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12 September 2017

M P Woods

7

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Europe PubMed Central

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12 September 2017

J E Hopper

8

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12 September 2017

language of work or name

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publication date

1 November 1999

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12 September 2017

Molecular and Cellular Biology

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12 September 2017

19

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Europe PubMed Central

PMC publication ID

12 September 2017

11

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

7828-7840

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Regulated phosphorylation of the Gal4p inhibitor Gal80p of Kluyveromyces lactis revealed by mutational analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

A transcriptional activating region with two contrasting modes of protein interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

An activator target in the RNA polymerase II holoenzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

The DNA binding and activation domains of Gal4p are sufficient for conveying its regulatory signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Galactose-dependent reversible interaction of Gal3p with Gal80p in the induction pathway of Gal4p-activated genes of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Phosphorylation of Ga14p at a single C-terminal residue is necessary for galactose-inducible transcription

1 reference

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A new efficient gene disruption cassette for repeated use in budding yeast

1 reference

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12 September 2017

Analysis of the galactose signal transduction pathway in Saccharomyces cerevisiae: interaction between Gal3p and Gal80p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Analyzing protein-protein interactions using two-hybrid system

1 reference

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12 September 2017

Ras-Raf interaction: two-hybrid analysis

1 reference

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12 September 2017

Expression of the transcriptional activator LAC9 (KlGAL4) in Kluyveromyces lactis is controlled by autoregulation

1 reference

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12 September 2017

GAL4 is regulated by a glucose-responsive functional domain.

1 reference

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12 September 2017

Autoregulation of GAL4 transcription is essential for rapid growth of Kluyveromyces lactis on lactose and galactose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

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12 September 2017

Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

GAL4 interacts with TATA-binding protein and coactivators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

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A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1 reference

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12 September 2017

Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Regulation of basal and induced levels of the MEL1 transcript in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Disruption of Regulatory Gene GAL80 in Saccharomyces cerevisiae: Effects on Carbon-Controlled Regulation of the Galactose/Melibiose Pathway Genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Uninducible Mutants in the gal i Locus of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Specific protein binding to far upstream activating sequences in polymerase II promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Transcription of the ADH2 gene in Saccharomyces cerevisiae is limited by positive factors that bind competitively to its intact promoter region on multicopy plasmids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Interaction of GAL4 and GAL80 gene regulatory proteins in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Interaction of positive and negative regulatory proteins in the galactose regulon of yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

A new class of yeast transcriptional activators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

GAL4 of Saccharomyces cerevisiae activates the lactose-galactose regulon of Kluyveromyces lactis and creates a new phenotype: glucose repression of the regulon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Mutational analysis of the GAL4-encoded transcriptional activator protein of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

The organization and transcription of the galactose gene cluster of Kluyveromyces lactis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

GAL4-VP16 is an unusually potent transcriptional activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Deletion analysis of GAL4 defines two transcriptional activating segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Genetic and molecular analysis of the GAL3 gene in the expression of the galactose/melibiose regulon of Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

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12 September 2017

Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Analysis of the GAL3 signal transduction pathway activating GAL4 protein-dependent transcription in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

GAL4 mutations that separate the transcriptional activation and GAL80-interactive functions of the yeast GAL4 protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

Galactokinase encoded by GAL1 is a bifunctional protein required for induction of the GAL genes in Kluyveromyces lactis and is able to suppress the gal3 phenotype in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

One-step transformation of yeast in stationary phase

1 reference

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12 September 2017

Improved method for high efficiency transformation of intact yeast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

12 September 2017

DNA recognition by GAL4: structure of a protein-DNA complex.

1 reference

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12 September 2017

A simplification of the protein assay method of Lowry et al. which is more generally applicable

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12 September 2017

Overproduction of the GAL1 or GAL3 Protein Causes Galactose-Independent Activation of the GAL4 Protein: Evidence for a New Model of Induction for the Yeast GAL/MEL Regulon

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12 September 2017

Novel Gal3 proteins showing altered Gal80p binding cause constitutive transcription of Gal4p-activated genes in Saccharomyces cerevisiae

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14 September 2017

Gal80 proteins of Kluyveromyces lactis and Saccharomyces cerevisiae are highly conserved but contribute differently to glucose repression of the galactose regulon

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14 September 2017

Transcriptional regulation in the yeast GAL gene family: a complex genetic network

1 reference

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14 September 2017

Nucleotide sequence of the yeast regulatory gene GAL80.

1 reference

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14 September 2017

The presence of a defective LEU2 gene on 2 mu DNA recombinant plasmids of Saccharomyces cerevisiae is responsible for curing and high copy number.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

14 September 2017

GAL3 gene product is required for maintenance of the induced state of the GAL cluster genes in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

14 September 2017

Analysis of the Kluyveromyces lactis positive regulatory gene LAC9 reveals functional homology to, but sequence divergence from, the Saccharomyces cerevisiae GAL4 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

14 September 2017

Quantitation of putative activator-target affinities predicts transcriptional activating potentials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

25 September 2017

Interaction of super-repressible and dominant constitutive mutations for the synthesis of galactose pathway enzymes in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

25 September 2017

Galactose regulation in Saccharomyces cerevisiae. The enzymes encoded by the GAL7, 10, 1 cluster are co-ordinately controlled and separately translated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

25 September 2017

The transcription factor LAC9 from Kluyveromyces lactis-like GAL4 from Saccharomyces cerevisiae forms a Zn(II)2Cys6 binuclear cluster.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

25 September 2017

The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

17 June 2018

Signaling activation and repression of RNA polymerase II transcription in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

17 June 2018

Precise gene disruption in Saccharomyces cerevisiae by double fusion polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

17 June 2018

Molecular cloning of the GAL80 gene from Saccharomyces cerevisiae and characterization of a gal80 deletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

17 June 2018

Autogenous regulation of the Saccharomyces cerevisiae regulatory gene GAL80.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

17 June 2018

Nondissociation of GAL4 and GAL80 in vivo after galactose induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

17 June 2018

Curing of Saccharomyces cerevisiae 2-μm DNA by transformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

21 August 2018

Protein import into mitochondria in a homologous yeast in vitro system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

21 August 2018

An amino-terminal fragment of GAL4 binds DNA as a dimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84853

21 August 2018

Structural dissection of the DNA-binding domain of the yeast transcriptional activator GAL4 reveals an alpha-helical region responsible for dimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/10523671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mRNA levels for the fermentative alcohol dehydrogenase of Saccharomyces cerevisiae decrease upon growth on a nonfermentable carbon source

1 reference

https://pubmed.ncbi.nlm.nih.gov/10523671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Gal4p by galactose-dependent interaction of galactokinase and Gal80p

1 reference

https://pubmed.ncbi.nlm.nih.gov/10523671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic evidence that an activation domain of GAL4 does not require acidity and may form a beta sheet

1 reference

https://pubmed.ncbi.nlm.nih.gov/10523671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling of cytosolic protein synthesis and mitochondrial protein import in yeast. Evidence for cotranslational import in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10523671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10523671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80

1 reference

https://pubmed.ncbi.nlm.nih.gov/10523671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient expression of the Saccharomyces cerevisiae glycolytic gene ADH1 is dependent upon a cis-acting regulatory element (UASRPG) found initially in genes encoding ribosomal proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10523671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulated GAL4 expression cassette providing controllable and high-level output from high-copy galactose promoters in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/10523671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.19.11.7828

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

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