Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma (Q39063025)

8 September 2017

title

Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma (English)

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8 September 2017

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Yung-Ming Jeng

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Hsin-Jung Lee

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8 September 2017

Yu-Ling Chen

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8 September 2017

Ling Chung

series ordinal

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8 September 2017

language of work or name

English

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publication date

14 November 2013

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8 September 2017

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8 September 2017

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8 September 2017

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8 September 2017

page(s)

769-775

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Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

8 September 2017

cites work

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

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The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

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AXL is a potential target for therapeutic intervention in breast cancer progression.

21 January 2018

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Expression of axl in lung adenocarcinoma and correlation with tumor progression

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Gas6 induces proliferation in prostate carcinoma cell lines expressing the Axl receptor.

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Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma

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Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34.

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TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer

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Requirement of Phosphatidylinositol 3-Kinase-Dependent Pathway and Src for Gas6-Axl Mitogenic and Survival Activities in NIH 3T3 Fibroblasts

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Vitamin K-dependent Gas6 activates ERK kinase and stimulates growth of cardiac fibroblasts

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The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

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The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: implications for therapy

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Insulin-like growth factor I receptor β expression in hepatocellular carcinoma

21 January 2018

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Expression of the Axl receptor tyrosine kinase in human thyroid carcinoma

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Coexpression of growth arrest-specific gene 6 and receptor tyrosine kinases Axl and Sky in human uterine endometrial cancers

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Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells

21 January 2018

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Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival

21 January 2018

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Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-kappaB and Brg-1.

21 January 2018

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EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.

21 January 2018

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Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGT372

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8 September 2017

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