Tyrosine 397 phosphorylation is critical for FAK-promoted Rac1 activation and invasive properties in oral squamous cell carcinoma cells. (Q38804850)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Tyrosine 397 phosphorylation is critical for FAK-promoted Rac1 activation and invasive properties in oral squamous cell carcinoma cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

oral squamous cell carcinoma

4 March 2020

main subject

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Ya-Wen Chiu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Li-Yin Liou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Pin-Ting Chen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Chieh-Ming Huang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Fuh-Jinn Luo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Yu-Kan Hsu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

language of work or name

1 reference

11 January 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

published in

Laboratory Investigation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

296-306

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26752742%20AND%20SRC:MED&resulttype=core&format=json

Differential gene expression signature between primary and metastatic head and neck squamous cell carcinoma

4 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Focal adhesion kinase: in command and control of cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Elevated focal adhesion kinase expression facilitates oral tumor cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Focal adhesion kinase serves as a marker of cervical lymph node metastasis and is a potential therapeutic target in tongue cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Overexpression of Rac-1 small GTPase binding protein in oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Overexpression of cortactin increases invasion potential in oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Cortactin as a target for FAK in the regulation of focal adhesion dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Rac1 GTPase: a "Rac" of all trades.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Activated Vav2 modulates cellular invasion through Rac1 and Cdc42 in oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Inhibition of the synthesis of eicosanoid-like substances in a human oral cancer cell line by interferon-gamma and eicosapentaenoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

A new human cell line (FaDu) from a hypopharyngeal carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Regulation of estrogen receptor α function in oral squamous cell carcinoma cells by FAK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

ErbB-2 via PYK2 upregulates the adhesive ability of androgen receptor-positive human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

In oral squamous cell carcinoma, high FAK expression is correlated with low P53 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Structural basis for the autoinhibition of focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Rho GTPases: functions and association with cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Activation of FAK/PI3K/Rac1 signaling controls actin reorganization and inhibits cell motility in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Cortactin Overexpression Regulates Actin-Related Protein 2/3 Complex Activity, Motility, and Invasion in Carcinomas with Chromosome 11q13 Amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2015.151

Focal adhesion kinase and cancer

21 January 2018

1 reference

12 December 2020

Demographics and occurrence of oral and pharyngeal cancers. The outcomes, the trends, the challenge

1 reference

12 December 2020

Anti-tumor effect of a novel FAK inhibitor TAE226 against human oral squamous cell carcinoma

1 reference

12 December 2020

Detection of copy number amplification of cyclin D1 (CCND1) and cortactin (CTTN) in oral carcinoma and oral brushed samples from areca chewers

1 reference

12 December 2020

Amplifications of TAOS1 and EMS1 genes in oral carcinogenesis: association with clinicopathological features

1 reference

12 December 2020