Shp deletion prevents hepatic steatosis and when combined with Fxr loss protects against type 2 diabetes (Q38740970)

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scientific article published on 06 June 2017

Language	Label	Description	Also known as
English	Shp deletion prevents hepatic steatosis and when combined with Fxr loss protects against type 2 diabetes	scientific article published on 06 June 2017

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Shp deletion prevents hepatic steatosis and when combined with Fxr loss protects against type 2 diabetes (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

1 reference

based on heuristic

inferred from title

type 2 diabetes

1 reference

based on heuristic

inferred from title

object named as

type 2 diabetes

9 December 2023

Kristina Schoonjans

8

object named as

Kristina Schoonjans

0 references

Ann Marie Zavacki

7

object named as

Ann M Zavacki

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

author name string

Oludemilade Akinrotimi

1

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Ryan Riessen

2

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Philip VanDuyne

3

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Jung Eun Park

4

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Yoon Kwang Lee

5

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Lee-Jun Wong

6

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Sayeepriyadarshini Anakk

9

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

language of work or name

0 references

publication date

6 June 2017

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Human fatty liver disease: old questions and new insights

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Mechanisms for insulin resistance: common threads and missing links

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Nuclear receptors and the control of metabolism

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Genetic variation in NR1H4 encoding the bile acid receptor FXR determines fasting glucose and free fatty acid levels in humans

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Loss of small heterodimer partner protects against atherosclerosis in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Farnesoid X receptor is essential for normal glucose homeostasis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Loss of small heterodimer partner expression in the liver protects against dyslipidemia

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Nuclear receptors reverse McGarry's vicious cycle to insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

NCoR1 is a conserved physiological modulator of muscle mass and oxidative function

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

The mitochondrial 13513G>A mutation is associated with Leigh disease phenotypes independent of complex I deficiency in muscle

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Leptin and the regulation of body weight in mammals

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Selective activation of PPARgamma in skeletal muscle induces endogenous production of adiponectin and protects mice from diet-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

CIDEC/FSP27 is regulated by peroxisome proliferator-activated receptor alpha and plays a critical role in fasting- and diet-induced hepatosteatosis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Transcriptional activation of Fsp27 by the liver-enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

TGR5-mediated bile acid sensing controls glucose homeostasis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

21 January 2018

Mutations in the small heterodimer partner gene increase morbidity risk in Japanese type 2 diabetes patients

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

7 January 2021

based on heuristic

inferred from DOI database lookup

The repression of hormone-activated PEPCK gene expression by glucose is insulin-independent but requires glucose metabolism

1 reference

https://api.crossref.org/works/10.1002%2FHEP.29305

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/HEP.29305

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

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