mTOR controls ChREBP transcriptional activity and pancreatic β cell survival under diabetic stress (Q38401961)

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scientific article published on 12 June 2017

Language	Label	Description	Also known as
English	mTOR controls ChREBP transcriptional activity and pancreatic β cell survival under diabetic stress	scientific article published on 12 June 2017

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scholarly article

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Europe PubMed Central

PMC publication ID

8 January 2018

http://europepmc.org/abstract/PMC/5496625

mTOR controls ChREBP transcriptional activity and pancreatic β cell survival under diabetic stress (English)

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Europe PubMed Central

PMC publication ID

8 January 2018

http://europepmc.org/abstract/PMC/5496625

2

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31 May 2020

5

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31 May 2020

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31 May 2020

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Gia Cac Chau

1

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31 May 2020

Tong Mook Kang

3

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31 May 2020

Jeong Mo Bae

4

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31 May 2020

Suhkneung Pyo

6

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31 May 2020

Eun-Yi Moon

7

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31 May 2020

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12 June 2017

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15

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Journal of Cell Biology

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31 May 2020

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31 May 2020

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31 May 2020

2091-2105

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31 May 2020

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Benexate hydrochloride betadex modulates nitric oxide synthesis and cytokine expression in gastric ulcers

1 reference

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23 June 2018

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

1 reference

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23 June 2018

Sestrin2 is a leucine sensor for the mTORC1 pathway

1 reference

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23 June 2018

mTOR inhibitors and diabetes

1 reference

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23 June 2018

Diabetes mellitus: The epidemic of the century

1 reference

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23 June 2018

S6K1 controls pancreatic β cell size independently of intrauterine growth restriction

1 reference

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23 June 2018

Role of pro-inflammatory cytokines of pancreatic islets and prospects of elaboration of new methods for the diabetes treatment

1 reference

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23 June 2018

Nutrient-sensing mechanisms and pathways.

1 reference

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MondoA-Mlx transcriptional activity is limited by mTOR-MondoA interaction

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Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring

1 reference

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Minireview: Thioredoxin-interacting protein: regulation and function in the pancreatic β-cell

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23 June 2018

β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment

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23 June 2018

Making new contacts: the mTOR network in metabolism and signalling crosstalk

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23 June 2018

Rapamycin: one drug, many effects

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23 June 2018

Autophagy regulation by nutrient signaling

1 reference

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23 June 2018

Evidence for rapamycin toxicity in pancreatic β-cells and a review of the underlying molecular mechanisms.

1 reference

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23 June 2018

The role of thioredoxin 1 in the mycophenolic acid-induced apoptosis of insulin-producing cells

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23 June 2018

FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496625

23 June 2018

Mitochondrial function and insulin secretion.

1 reference

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23 June 2018

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

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23 June 2018

Nutrient signaling to mTOR and cell growth

1 reference

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23 June 2018

Positive feedback control between STIM1 and NFATc3 is required for C2C12 myoblast differentiation

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23 June 2018

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

1 reference

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23 June 2018

Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome

1 reference

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23 June 2018

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

1 reference

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23 June 2018

mTOR signaling in growth control and disease

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23 June 2018

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway

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S6 kinase 2 deficiency enhances ketone body production and increases peroxisome proliferator-activated receptor alpha activity in the liver

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23 June 2018

Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1

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23 June 2018

L-arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge

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23 June 2018

Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size

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23 June 2018

mTOR: from growth signal integration to cancer, diabetes and ageing

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23 June 2018

Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice

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23 June 2018

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

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Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue

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Critical roles for the TSC-mTOR pathway in β-cell function

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Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells

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Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

1 reference

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Disruption of Tsc2 in pancreatic beta cells induces beta cell mass expansion and improved glucose tolerance in a TORC1-dependent manner.

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Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

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Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes

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The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells

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Intrinsic regulators of pancreatic beta-cell proliferation

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23 June 2018

Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module

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23 June 2018

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

1 reference

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23 June 2018

Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells

1 reference

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Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus

1 reference

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23 June 2018

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1 reference

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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

1 reference

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Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

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1 reference

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1 reference

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1 reference

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Metabolic regulation by leucine of translation initiation through the mTOR-signaling pathway by pancreatic beta-cells

1 reference

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23 June 2018

Triggering and amplifying pathways of regulation of insulin secretion by glucose

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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31 August 2018

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10.1083/JCB.201701085

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28606928%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28606928%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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Europe PubMed Central

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31 May 2020

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