A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions. (Q38479036)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17916792%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions (English)

1 reference

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8 January 2020

Michael J Chalmers

1 reference

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8 January 2020

Scott A Busby

1 reference

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8 January 2020

Bruce D Pascal

1 reference

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8 January 2020

Mark R Southern

1 reference

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8 January 2020

Patrick R Griffin

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8 January 2020

publication date

1 September 2007

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Journal of Biomolecular Techniques

8 January 2020

published in

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8 January 2020

volume

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8 January 2020

issue

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8 January 2020

page(s)

194-204

1 reference

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The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data

8 January 2020

cites work

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Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry

6 September 2017

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6 September 2017

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Solvent accessibility of native and hydrolyzed human complement protein 3 analyzed by hydrogen/deuterium exchange and mass spectrometry.

6 September 2017

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Insights into enzyme structure and dynamics elucidated by amide H/D exchange mass spectrometry.

6 September 2017

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6 September 2017

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A new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects

6 September 2017

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Hydrogen/deuterium exchange mass spectrometry for investigating protein-ligand interactions.

6 September 2017

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Mass spectrometric approaches using electrospray ionization charge states and hydrogen-deuterium exchange for determining protein structures and their conformational changes

6 September 2017

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Rapid analysis of protein structure and dynamics by hydrogen/deuterium exchange mass spectrometry.

6 September 2017

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Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions

6 September 2017

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The nuclear receptor superfamily

6 September 2017

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Investigating protein structure and dynamics by hydrogen exchange MS.

6 September 2017

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Raloxifene, a new selective estrogen receptor modulator

6 September 2017

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Medical significance of peroxisome proliferator-activated receptors.

6 September 2017

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Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma

6 September 2017

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

6 September 2017

1 reference

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Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

6 September 2017

1 reference

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Hydrogen exchange: the modern legacy of Linderstrøm-Lang

6 September 2017

1 reference

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The nuclear receptor superfamily: the second decade

6 September 2017

1 reference

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A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

6 September 2017

1 reference

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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

6 September 2017

1 reference

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Determination of amide hydrogen exchange by mass spectrometry: a new tool for protein structure elucidation

6 September 2017

1 reference

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Primary structure effects on peptide group hydrogen exchange

6 September 2017

1 reference

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Hydrogen exchange and structural dynamics of proteins and nucleic acids

6 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2062560

6 September 2017

https://pubmed.ncbi.nlm.nih.gov/17916792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2062560

Nerve growth factor activation of the extracellular signal-regulated kinase pathway is modulated by Ca(2+) and calmodulin.

6 September 2017

1 reference

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A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2062560

Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators

27 September 2017

1 reference

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Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator

23 June 2018

1 reference

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The activity of PPAR gamma in primary human trophoblasts is enhanced by oxidized lipids

23 June 2018

1 reference

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Kinetics of unfolding and folding from amide hydrogen exchange in native ubiquitin

23 June 2018

1 reference

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A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor gamma-activating properties

23 June 2018

1 reference

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Touring the landscapes: partially folded proteins examined by hydrogen exchange

23 June 2018

1 reference

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Functional visualization of viral molecular motor by hydrogen-deuterium exchange reveals transient states

23 June 2018

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Benzoyl 2-methyl indoles as selective PPARgamma modulators

31 August 2018

1 reference

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Dynamics and ligand-induced solvent accessibility changes in human retinoid X receptor homodimer determined by hydrogen deuterium exchange and mass spectrometry

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2062560

Dynamics of cAPK type IIbeta activation revealed by enhanced amide H/2H exchange mass spectrometry (DXMS).

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2062560

Phosphorylation driven motions in the COOH-terminal Src kinase, CSK, revealed through enhanced hydrogen-deuterium exchange and mass spectrometry (DXMS).

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2062560

Thiazolidinediones: an update.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2062560

Ultra performance liquid chromatography (UPLC) further improves hydrogen/deuterium exchange mass spectrometry

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2062560

Probing the structure of the infectious amyloid form of the prion-forming domain of HET-s using high resolution hydrogen/deuterium exchange monitored by mass spectrometry

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17916792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Activity of PPARγ in Primary Human Trophoblasts Is Enhanced by Oxidized Lipids

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17916792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

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8 January 2020

PubMed publication ID

17916792

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17916792%20AND%20SRC:MED&resulttype=core&format=json