The estrogen receptor from a tamoxifen stimulated MCF-7 tumor variant contains a point mutation in the ligand binding domain (Q38312744)

2 September 2017

title

The estrogen receptor from a tamoxifen stimulated MCF-7 tumor variant contains a point mutation in the ligand binding domain (English)

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2 September 2017

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V C Jordan

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2 September 2017

D M Wolf

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2 September 2017

language of work or name

English

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publication date

1 January 1994

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Breast Cancer Research and Treatment

2 September 2017

published in

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2 September 2017

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2 September 2017

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2 September 2017

page(s)

129-138

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Point mutation of estrogen receptor (ER) in the ligand-binding domain changes the pharmacology of antiestrogens in ER-negative breast cancer cells stably expressing complementary DNAs for ER.

2 September 2017

cites work

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12 December 2020

Response after withdrawal of tamoxifen and progestogens in advanced breast cancer

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12 December 2020

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

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12 December 2020

Investigation of the mechanism of tamoxifen-stimulated breast tumor growth with nonisomerizable analogues of tamoxifen and metabolites.

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Unusual specificity of the androgen receptor in the human prostate tumor cell line LNCaP: high affinity for progestagenic and estrogenic steroids

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Randomized clinical trial of diethylstilbestrol versus tamoxifen in postmenopausal women with advanced breast cancer

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Stimulatory effects of antiandrogens on LNCaP human prostate tumor cell growth, EGF-receptor level and acid phosphatase secretion

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The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

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12 December 2020

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

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12 December 2020

Identification of estrogenic tamoxifen metabolite(s) in tamoxifen-resistant human breast tumors

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12 December 2020

Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor

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12 December 2020

Tamoxifen withdrawal response. Report of a case

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12 December 2020

Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration

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12 December 2020

Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors

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12 December 2020

Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Early Breast Cancer Trialists' Collaborative Group

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12 December 2020

Influence of the antioestrogen tamoxifen on normal breast tissue

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12 December 2020

Aberrant response in vitro of hormone-responsive prostate cancer cells to antiandrogens

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12 December 2020

Reversible control of oestradiol-stimulated growth of MCF-7 tumours by tamoxifen in the athymic mouse

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12 December 2020

Tamoxifen versus aminoglutethimide in advanced breast carcinoma: a randomized cross-over trial

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12 December 2020

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

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12 December 2020

Tamoxifen and the isomers of 4-hydroxytamoxifen in tamoxifen-resistant tumors from breast cancer patients

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12 December 2020

Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens.

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12 December 2020

The proliferative effect of "anti-androgens" on the androgen-sensitive human prostate tumor cell line LNCaP.

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12 December 2020

Clinical significance of tamoxifen withdrawal response

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12 December 2020

Tamoxifen-induced tumor stimulation and withdrawal response

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12 December 2020

A model to describe how a point mutation of the estrogen receptor alters the structure-function relationship of antiestrogens

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12 December 2020

Detection of point mutations by SSCP of PCR-amplified DNA after endonuclease digestion

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12 December 2020

Acquired tamoxifen resistance: correlation with reduced breast tumor levels of tamoxifen and isomerization of trans-4-hydroxytamoxifen.

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12 December 2020

A New Anti-oestrogenic Agent in Late Breast Cancer: An Early Clinical Appraisal of ICI46474

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12 December 2020

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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12 December 2020

The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties

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12 December 2020

Human breast cancer in the athymic nude mouse: cytostatic effects of long-term antiestrogen therapy

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12 December 2020

A rapid and convenient method for the preparation and storage of competent bacterial cells

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12 December 2020

Characterization of tamoxifen stimulated MCF-7 tumor variants grown in athymic mice

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12 December 2020

A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens

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12 December 2020

Identifiers

DOI

10.1007/BF00689683

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Dimensions Publication ID

2 September 2017

1052772508

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