Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety. (Q38126945)

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scientific article published on 07 August 2013

Language	Label	Description	Also known as
English	Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety.	scientific article published on 07 August 2013

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety. (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

author name string

Jens J Holst

2

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

publication date

7 August 2013

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

Expert Opinion on Pharmacotherapy

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

2047-2058

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

The Physiology of Glucagon-like Peptide 1

1 reference

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21 January 2018

Plasma Insulin Responses to Oral and Intravenous Glucose: Studies in Normal and Diabetic Subjects*

1 reference

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21 January 2018

Glucagon-like peptide-1, glucose homeostasis and diabetes

1 reference

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21 January 2018

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

1 reference

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21 January 2018

Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients

1 reference

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21 January 2018

Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients

1 reference

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21 January 2018

Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study

1 reference

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21 January 2018

Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM.

1 reference

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21 January 2018

Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review

1 reference

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21 January 2018

Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans

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21 January 2018

Efficacy of GLP-1 receptor agonists and DPP-4 inhibitors: meta-analysis and systematic review

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21 January 2018

Efficacy and safety of dipeptidyl peptidase-4 inhibitors in type 2 diabetes: meta-analysis.

1 reference

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21 January 2018

Efficacy and safety of saxagliptin in combination with metformin compared with sitagliptin in combination with metformin in adult patients with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations

1 reference

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21 January 2018

Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition

1 reference

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21 January 2018

Continuous glucose profiles with vildagliptin versus sitagliptin in add-on to metformin: results from the randomized Optima study

1 reference

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21 January 2018

A decrease in glucose variability does not reduce cardiovascular event rates in type 2 diabetic patients after acute myocardial infarction: a reanalysis of the HEART2D study

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes

1 reference

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21 January 2018

Statement by an American Association of Clinical Endocrinologists/American College of Endocrinology consensus panel on type 2 diabetes mellitus: an algorithm for glycemic control

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1.

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Alogliptin use in elderly people: a pooled analysis from phase 2 and 3 studies

1 reference

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21 January 2018

Efficacy and tolerability of sitagliptin monotherapy in elderly patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial

1 reference

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21 January 2018

Clinical experience with vildagliptin in the management of type 2 diabetes in a patient population ≥75 years: a pooled analysis from a database of clinical trials

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Suicide attempt by an overdose of sitagliptin, an oral hypoglycemic agent: a case report and a review of the literature

1 reference

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21 January 2018

Differences in the glucose-lowering efficacy of dipeptidyl peptidase-4 inhibitors between Asians and non-Asians: a systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Dipeptidyl peptidase-4 inhibitors for treatment of type 2 diabetes mellitus in the clinical setting: systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Safety and efficacy of treatment with sitagliptin or glipizide in patients with type 2 diabetes inadequately controlled on metformin: a 2-year study

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

A comparison of efficacy and safety of vildagliptin and gliclazide in combination with metformin in patients with Type 2 diabetes inadequately controlled with metformin alone: a 52-week, randomized study

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes-a review and meta analysis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Efficacy and safety of sitagliptin versus glipizide in patients with type 2 diabetes and moderate-to-severe chronic renal insufficiency

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Long-term efficacy and safety of linagliptin in patients with type 2 diabetes and severe renal impairment: a 1-year, randomized, double-blind, placebo-controlled study

1 reference

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21 January 2018

Vildagliptin and pioglitazone in patients with impaired glucose tolerance after kidney transplantation: a randomized, placebo-controlled clinical trial

1 reference

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21 January 2018

An assessment of adverse effects of vildagliptin versus comparators on the liver, the pancreas, the immune system, the skin and in patients with impaired renal function from a large pooled database of Phase II and III clinical trials

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Safety of dipeptidyl peptidase-4 inhibitors: a meta-analysis of randomized clinical trials

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Longer term safety of dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes mellitus: systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

The efficacy and safety of vildagliptin in patients with type 2 diabetes: a meta-analysis of randomized clinical trials

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Safety and tolerability of sitagliptin in type 2 diabetes: pooled analysis of 25 clinical studies

1 reference

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21 January 2018

Dipeptidyl peptidase IV inhibition does not adversely affect immune or virological status in HIV infected men and women: a pilot safety study

1 reference

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21 January 2018

Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: a retrospective cohort study

1 reference

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21 January 2018

Acute pancreatitis in type 2 diabetes treated with exenatide or sitagliptin: a retrospective observational pharmacy claims analysis

1 reference

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21 January 2018

Patients with type 2 diabetes mellitus have higher risk for acute pancreatitis compared with those without diabetes

1 reference

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21 January 2018

Type 2 diabetes mellitus and the risk of acute pancreatitis: a meta-analysis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin

1 reference

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21 January 2018

Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model

1 reference

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21 January 2018

Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreas

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Glucagon-like peptide-1 receptor activation modulates pancreatitis-associated gene expression but does not modify the susceptibility to experimental pancreatitis in mice

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodents

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Sitagliptin: review of preclinical and clinical data regarding incidence of pancreatitis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Studies in rodents with the dipeptidyl peptidase-4 inhibitor vildagliptin to evaluate possible drug-induced pancreatic histological changes that are predictive of pancreatitis and cancer development in man.

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

The human GLP-1 analog liraglutide and the pancreas: evidence for the absence of structural pancreatic changes in three species.

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Pancreatitis associated with the use of sitagliptin and orlistat combination: a case report

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Glucagonlike peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Pancreatitis, Pancreatic, and Thyroid Cancer With Glucagon-Like Peptide-1–Based Therapies

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

The safety of incretin-based therapies--review of the scientific evidence

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Gliptins (dipeptidyl peptidase-4 inhibitors) and risk of acute pancreatitis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Incretin therapy and islet pathology: a time for caution

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Assessing the general safety and tolerability of vildagliptin: value of pooled analyses from a large safety database versus evaluation of individual studies

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Safety and tolerability of linagliptin: a pooled analysis of data from randomized controlled trials in 3572 patients with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Tolerability of dipeptidyl peptidase-4 inhibitors: a review

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

1 reference

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21 January 2018

Renal and cardiac effects of DPP4 inhibitors--from preclinical development to clinical research

1 reference

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21 January 2018

Diabetic nephropathy amelioration by a low-dose sitagliptin in an animal model of type 2 diabetes (Zucker diabetic fatty rat).

1 reference

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21 January 2018

Sitagliptin reduces albuminuria in patients with type 2 diabetes

1 reference

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21 January 2018

Characteristics of patients prescribed sitagliptin and other oral antihyperglycaemic agents in a large US claims database

1 reference

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21 January 2018

A critical analysis of the clinical use of incretin-based therapies: The benefits by far outweigh the potential risks

1 reference

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21 January 2018

A critical analysis of the clinical use of incretin-based therapies: Are the GLP-1 therapies safe?

1 reference

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21 January 2018

Potential cardiovascular effects of incretin-based therapies

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Dipeptidyl peptidase-4 inhibitors and cardiovascular risk: a meta-analysis of randomized clinical trials

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Assessing the cardio-cerebrovascular safety of vildagliptin: meta-analysis of adjudicated events from a large Phase III type 2 diabetes population

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: a pre-specified, prospective, and adjudicated meta-analysis of a phase 3 programme

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Cardiovascular safety of sitagliptin in patients with type 2 diabetes mellitus: a pooled analysis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Cardiovascular safety of the dipetidyl peptidase-4 inhibitor alogliptin in type 2 diabetes mellitus

1 reference

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21 January 2018

Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction.

1 reference

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21 January 2018

The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: possible role of stromal-derived factor-1alpha.

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Safety and efficacy of SITAgliptin plus GRanulocyte-colony-stimulating factor in patients suffering from Acute Myocardial Infarction (SITAGRAMI-Trial)--rationale, design and first interim analysis

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Both Subcutaneously and Intravenously Administered Glucagon-Like Peptide I Are Rapidly Degraded From the NH2-Terminus in Type II Diabetic Patients and in Healthy Subjects

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.824966

21 January 2018

Identifiers

10.1517/14656566.2013.824966

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 August 2017

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