Understanding the basic mechanisms underlying seizures in mesial temporal lobe epilepsy and possible therapeutic targets: a review. (Q37982345)

26 August 2017

title

Understanding the basic mechanisms underlying seizures in mesial temporal lobe epilepsy and possible therapeutic targets: a review. (English)

1 reference

26 August 2017

Casey M O'Dell

1 reference

26 August 2017

Arabinda Das

1 reference

26 August 2017

Gerald Wallace

1 reference

26 August 2017

Swapan K Ray

1 reference

26 August 2017

Naren L Banik

1 reference

26 August 2017

publication date

8 February 2012

1 reference

Journal of Neuroscience Research

26 August 2017

published in

1 reference

26 August 2017

1 reference

26 August 2017

1 reference

26 August 2017

page(s)

913-924

1 reference

Calpains and delayed calcium deregulation in excitotoxicity.

26 August 2017

cites work

1 reference

The renin-angiotensin system is upregulated in the cortex and hippocampus of patients with temporal lobe epilepsy related to mesial temporal sclerosis.

21 January 2018

1 reference

Upregulation of adenosine kinase in astrocytes in experimental and human temporal lobe epilepsy

21 January 2018

1 reference

Neuropathologic and clinical features of human medial temporal lobe epilepsy.

21 January 2018

1 reference

Does acquired epileptogenesis in the immature brain require neuronal death

21 January 2018

1 reference

Primary and secondary mechanisms of epileptogenesis in the temporal lobe: there is a before and an after.

21 January 2018

1 reference

The adenosine kinase hypothesis of epileptogenesis

21 January 2018

1 reference

Rapamycin suppresses axon sprouting by somatostatin interneurons in a mouse model of temporal lobe epilepsy

21 January 2018

1 reference

Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders

21 January 2018

1 reference

Inflammatory reactions in human medial temporal lobe epilepsy with hippocampal sclerosis

21 January 2018

1 reference

Post-treatment with voltage-gated Na(+) channel blocker attenuates kainic acid-induced apoptosis in rat primary hippocampal neurons

21 January 2018

1 reference

A retrospective analysis of hippocampal pathology in human temporal lobe epilepsy: evidence for distinctive patient subcategories

21 January 2018

1 reference

Panniculitis due to potassium bromide

21 January 2018

1 reference

Loss of perivascular aquaporin 4 may underlie deficient water and K+ homeostasis in the human epileptogenic hippocampus

21 January 2018

1 reference

Recurrent mossy fibers establish aberrant kainate receptor-operated synapses on granule cells from epileptic rats.

21 January 2018

1 reference

Overexpression of μ-calpain in the anterior temporal neocortex of patients with intractable epilepsy correlates with clinicopathological characteristics

21 January 2018

1 reference

GABAergic neurons and GABA(A)-receptors in temporal lobe epilepsy.

21 January 2018

1 reference

Developmental patterns in the regulation of chloride homeostasis and GABA(A) receptor signaling by seizures

21 January 2018

1 reference

Progression of spontaneous seizures after status epilepticus is associated with mossy fibre sprouting and extensive bilateral loss of hilar parvalbumin and somatostatin-immunoreactive neurons

21 January 2018

1 reference

Neuronal cell death in a rat model for mesial temporal lobe epilepsy is induced by the initial status epilepticus and not by later repeated spontaneous seizures

21 January 2018

1 reference

Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis

21 January 2018

1 reference

Therapy for hyperthermia-induced seizures in Scn1a mutant rats

21 January 2018

1 reference

Effects of SC58236, a selective COX-2 inhibitor, on epileptogenesis and spontaneous seizures in a rat model for temporal lobe epilepsy

21 January 2018

1 reference

The role of cytokines and growth factors in seizures and their sequelae

21 January 2018

1 reference

Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons

21 January 2018

1 reference

Drug interactions involving the new second- and third-generation antiepileptic drugs

21 January 2018

1 reference

Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus

21 January 2018

1 reference

Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats

21 January 2018

1 reference

21 January 2018

Posttraumatic epilepsy

1 reference

A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats

21 January 2018

1 reference

Antiepileptic Drug Development: I. History and a Program for Progress

21 January 2018

1 reference

Aquaporin-4 is increased in the sclerotic hippocampus in human temporal lobe epilepsy

21 January 2018

1 reference

Aberrant glutamate receptor 5 expression in temporal lobe epilepsy lesions

21 January 2018

1 reference

Ketogenic diet exhibits neuroprotective effects in hippocampus but fails to prevent epileptogenesis in the lithium-pilocarpine model of mesial temporal lobe epilepsy in adult rats

21 January 2018

1 reference

Modern antiepileptic drug development has failed to deliver: Ways out of the current dilemma

21 January 2018

1 reference

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders.

21 January 2018

1 reference

South African plants used in traditional medicine to treat epilepsy have an antagonistic effect on NMDA receptor currents

21 January 2018

1 reference

Antagonism of peripheral inflammation reduces the severity of status epilepticus.

21 January 2018

1 reference

Efficacy of anti-inflammatory therapy in a model of acute seizures and in a population of pediatric drug resistant epileptics

21 January 2018

1 reference

Neuroprotective effects of genistein in VSC4.1 motoneurons exposed to activated microglial cytokines

21 January 2018

1 reference

The Voltage-Sensing Domain of K(v)7.2 Channels as a Molecular Target for Epilepsy-Causing Mutations and Anticonvulsants.

21 January 2018

1 reference

Pharmacological inhibition of lipid peroxidation attenuates calpain-mediated cytoskeletal degradation after traumatic brain injury

21 January 2018

1 reference

Altered expression and function of small-conductance (SK) Ca(2+)-activated K+ channels in pilocarpine-treated epileptic rats

21 January 2018

1 reference

Midazolam and other benzodiazepines

21 January 2018

1 reference

Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus.

21 January 2018

1 reference

Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy

21 January 2018

1 reference

The COX-2 inhibitor parecoxib is neuroprotective but not antiepileptogenic in the pilocarpine model of temporal lobe epilepsy

21 January 2018

1 reference

Inflammation and prevention of epileptogenesis.

21 January 2018

1 reference

Inhibition of cysteine proteases in acute and chronic spinal cord injury

21 January 2018

1 reference

Presynaptic CLC-3 determines quantal size of inhibitory transmission in the hippocampus

21 January 2018

1 reference

Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent signalling in cortical but not in hippocampal neurons

21 January 2018

1 reference

Antiepileptogenic and anticonvulsant activity of interleukin-1 beta in amygdala-kindled rats.

21 January 2018

1 reference

Mesial temporal lobe epilepsy: pathogenesis, induced rodent models and lesions

21 January 2018

1 reference

Phenomenology of prolonged febrile seizures: results of the FEBSTAT study

21 January 2018

1 reference

Drug treatment of epilepsy in the century of the ILAE: the second 50 years, 1959-2009.

21 January 2018

1 reference

Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus

21 January 2018

1 reference

Brain inflammation in epilepsy: experimental and clinical evidence

21 January 2018

1 reference

The role of cytokines in the pathophysiology of epilepsy

21 January 2018

1 reference

ILAE Commission Report. Mesial temporal lobe epilepsy with hippocampal sclerosis.

21 January 2018

1 reference

Rapamycin for treatment of epilepsy: antiseizure, antiepileptogenic, both, or neither?

21 January 2018

1 reference

Why mesial temporal lobe epilepsy with hippocampal sclerosis is progressive: uncontrolled inflammation drives disease progression?

21 January 2018

1 reference

Dissofilm: a novel approach for delivery of phenobarbital; design and characterization

21 January 2018

1 reference

Activation of GluR6-containing Kainate Receptors Induces Ubiquitin-dependent Bcl-2 Degradation via Denitrosylation in the Rat Hippocampus after Kainate Treatment

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JNR.22829

1 reference

26 August 2017

1 reference