Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro. (Q37340505)

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scientific article published on June 2003

Language	Label	Description	Also known as
English	Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro.	scientific article published on June 2003

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799645%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799645%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

apoptotic process

0 references

zoledronic acid

1 reference

based on heuristic

inferred from title

pancreatic cancer

1 reference

based on heuristic

inferred from title

Camillo Palmieri

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799645%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Michele Caraglia

5

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4 November 2019

8

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Europe PubMed Central

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4 November 2019

author name string

P Tassone

1

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4 November 2019

P Tagliaferri

2

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4 November 2019

C Viscomi

3

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4 November 2019

A D'Alessandro

6

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4 November 2019

E Galea

7

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4 November 2019

A Abbruzzese

9

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4 November 2019

C R Boland

10

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4 November 2019

S Venuta

11

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4 November 2019

language of work or name

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publication date

1 June 2003

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4 November 2019

British Journal of Cancer

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4 November 2019

88

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4 November 2019

12

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4 November 2019

1971-1978

1 reference

Europe PubMed Central

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4 November 2019

The bisphosphonate zoledronic acid impairs Ras membrane [correction of impairs membrane] localisation and induces cytochrome c release in breast cancer cells

1 reference

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Rho GTPase signalling pathways in the morphological changes associated with apoptosis.

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6 September 2017

Chemical and biological prerequisites for novel bisphosphonate molecules: results of comparative preclinical studies

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6 September 2017

The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2741108

6 September 2017

Akt regulates cell survival and apoptosis at a postmitochondrial level

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6 September 2017

Bisphosphonates induce apoptosis in human breast cancer cell lines

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6 September 2017

Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

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6 September 2017

Molecular genetic basis of pancreatic adenocarcinoma

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6 September 2017

Actin cleavage by CPP-32/apopain during the development of apoptosis

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6 September 2017

Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro

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6 September 2017

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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6 September 2017

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

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6 September 2017

Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro

1 reference

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6 September 2017

Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure

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6 September 2017

Pharmacokinetics of pamidronate disodium in patients with cancer with normal or impaired renal function

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14 September 2017

Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line

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28 September 2017

Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs

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28 September 2017

Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity.

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28 September 2017

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

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28 September 2017

Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice

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28 September 2017

The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro.

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26 June 2018

Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma

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26 June 2018

Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

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26 June 2018

In vitro cytoreductive effects on multiple myeloma cells induced by bisphosphonates

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26 June 2018

Preclinical pharmacology of CGP 42'446, a new, potent, heterocyclic bisphosphonate compound

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26 June 2018

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26 June 2018

The IL-6 receptor super-antagonist Sant7 enhances antiproliferative and apoptotic effects induced by dexamethasone and zoledronic acid on multiple myeloma cells.

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Visualization of bisphosphonate-induced caspase-3 activity in apoptotic osteoclasts in vitro

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Bisphosphonate treatment inhibits the growth of prostate cancer cells

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Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group

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2 September 2018

Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices

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2 September 2018

Cancer statistics, 1996.

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2 September 2018

Trends in pancreatic cancer mortality in Europe, 1955–1989

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The clearance and bioavailability of pamidronate in patients with breast cancer and bone metastases

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Pamidronate treatment in patients with tumor-associated hypercalcemia: pharmacological effects and pharmacokinetics

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12 December 2020

based on heuristic

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Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo

1 reference

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12 December 2020

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Effects of the bisphosphonate olpadronate in patients with carcinoma of the prostate metastatic to the skeleton

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Anti-myeloma activity of pamidronate in vivo

1 reference

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Growth inhibition and synergistic induction of apoptosis by zoledronate and dexamethasone in human myeloma cell lines

1 reference

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Pelvic metastases from pancreatic carcinoma: a pattern observed on bone scan

1 reference

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12 December 2020

based on heuristic

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Identifiers

10.1038/SJ.BJC.6600986

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799645%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

PMC publication ID

1 reference

Europe PubMed Central

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4 November 2019

PubMed publication ID

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Europe PubMed Central

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4 November 2019

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