Anti-CTLA4 Antibody Clinical Trials in Melanoma (Q37234763)

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scientific article published on September 2007

Language	Label	Description	Also known as
English	Anti-CTLA4 Antibody Clinical Trials in Melanoma	scientific article published on September 2007

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Anti-CTLA4 Antibody Clinical Trials in Melanoma (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1 reference

based on heuristic

inferred from title

author name string

Antoni Ribas

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

publication date

1 September 2007

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Update on Cancer Therapeutics

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

133-139

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer

1 reference

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Cancer regression in patients after transfer of genetically engineered lymphocytes

1 reference

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Reversal of the TCR stop signal by CTLA-4

1 reference

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Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma

1 reference

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Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4

1 reference

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Biologic and immunomodulatory events after CTLA-4 blockade with ticilimumab in patients with advanced malignant melanoma

1 reference

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Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade

1 reference

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Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a phase I/II study

1 reference

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Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer

1 reference

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Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.

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Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.

1 reference

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Tumor immunotherapy: preclinical and clinical activity of anti-CTLA4 antibodies

1 reference

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Management of cutaneous melanoma

1 reference

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Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.

1 reference

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Palliative therapy of disseminated malignant melanoma: a systematic review of 41 randomised clinical trials.

1 reference

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6 September 2017

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699286

6 September 2017

Current developments in cancer vaccines and cellular immunotherapy

1 reference

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Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients

1 reference

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Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

1 reference

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CD4+ CD25+ suppressor T cells: more questions than answers

1 reference

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6 September 2017

Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

1 reference

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Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy

1 reference

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6 September 2017

Certified professionals: CD4(+)CD25(+) suppressor T cells

1 reference

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6 September 2017

CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy

1 reference

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6 September 2017

Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy.

1 reference

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6 September 2017

In vivo blockade of CTLA-4 enhances the priming of responsive T cells but fails to prevent the induction of tumor antigen-specific tolerance.

1 reference

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Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

1 reference

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Dendritic cell vaccines for cancer immunotherapy

1 reference

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6 September 2017

Enhancement of antitumor immunity by CTLA-4 blockade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699286

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

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CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction

1 reference

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Expression of CTLA-4 by human monocytes

1 reference

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Definition of an immunologic response using the major histocompatibility complex tetramer and enzyme-linked immunospot assays

1 reference

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3 September 2018

Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206.

1 reference

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Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma

1 reference

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Activity and safety of CTLA-4 blockade combined with vaccines in cynomolgus macaques

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1 reference

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CTLA-4-Ig regulates tryptophan catabolism in vivo.

1 reference

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Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade.

1 reference

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3 September 2018

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

1 reference

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CTL-associated antigen-4 ligation induces rapid T cell polarization that depends on phosphatidylinositol 3-kinase, Vav-1, Cdc42, and myosin light chain kinase

1 reference

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Cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma: a new cause of uveitis

1 reference

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The anti-tumor activity of anti-CTLA-4 is mediated through its induction of IFN gamma

1 reference

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Durable responses and long-term progression-free survival observed in a phase II study of MDX-010 alone or in combination with dacarbazine (DTIC) in metastatic melanoma

1 reference

18 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1200/JCO.2005.23.16_SUPPL.7525

Identifiers

10.1016/J.UCT.2007.09.001

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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